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Volumn 23, Issue 2, 2009, Pages 197-205

Evaluation of DNA damage and metabolic syndrome parameters in diabetic rabbits supplemented with antioxidants

Author keywords

Comet assay; DNA damage; Metabolic syndrome; Serum paraoxonase 1; Small dense low density lipoprotein

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; C REACTIVE PROTEIN; MALONALDEHYDE; TRIACYLGLYCEROL;

EID: 62849129058     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2009.00666.x     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 0242300698 scopus 로고    scopus 로고
    • Follow-up report on the diagnosis of diabetes mellitus: The expert committee on the diagnosis and classification of diabetes mellitus
    • Genuth S., Alberti K.G., Bennett P. Follow-up report on the diagnosis of diabetes mellitus: the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care (2003) 26 3160 3167.
    • (2003) Diabetes Care , vol.26 , pp. 3160-3167
    • Genuth, S.1    Alberti, K.G.2    Bennett, P.3
  • 2
    • 0023820924 scopus 로고
    • - radical generation by xanthine oxidase system of pancreatic β cells
    • - radical generation by xanthine oxidase system of pancreatic β cells. FEBS Lett. (1988) 239 295 298.
    • (1988) FEBS Lett. , vol.239 , pp. 295-298
    • Nukatsuka, M.1    Sakurai, H.2    Yoshimura, Y.3
  • 3
    • 33847414909 scopus 로고    scopus 로고
    • Evaluation of level of DNA damage in blood leucocytes of non-diabetic and diabetic rat exposed to cigarette smoke
    • Lima P.H.O., Sinzato Y.K., da Silva Soares de Souza M. et al. Evaluation of level of DNA damage in blood leucocytes of non-diabetic and diabetic rat exposed to cigarette smoke. Mutat. Res. (2007) 628 117 122.
    • (2007) Mutat. Res. , vol.628 , pp. 117-122
    • Lima, P.H.O.1    Sinzato, Y.K.2    Da Silva Soares De Souza, M.3
  • 4
    • 0842303109 scopus 로고    scopus 로고
    • Effects of vitamin e on oxidative stress and membrane fluidity in brain of streptozotocin-induced diabetic rats
    • Hong J.H., Kim M.J., Park M.R., Kwag O.G., Lee I.S., Byun B.H. Effects of vitamin E on oxidative stress and membrane fluidity in brain of streptozotocin-induced diabetic rats. Clin. Chim. Acta. (2004) 340 107 115.
    • (2004) Clin. Chim. Acta. , vol.340 , pp. 107-115
    • Hong, J.H.1    Kim, M.J.2    Park, M.R.3    Kwag, O.G.4    Lee, I.S.5    Byun, B.H.6
  • 5
    • 0013351813 scopus 로고    scopus 로고
    • Oxidative stress, alpha-tocopherol therapy and atherosclerosis
    • Harris A., Devaraj S., Jialal I. Oxidative stress, alpha-tocopherol therapy and atherosclerosis. Curr. Atheroscler. Rep. (2002) 4 373 380.
    • (2002) Curr. Atheroscler. Rep. , vol.4 , pp. 373-380
    • Harris, A.1    Devaraj, S.2    Jialal, I.3
  • 6
    • 0347916886 scopus 로고    scopus 로고
    • Molecular mechanisms of cholesterol or homocysteine effect in the development of atherosclerosis: Role of vitamin e
    • Kartal N.O., Negis Y., Aytan N. Molecular mechanisms of cholesterol or homocysteine effect in the development of atherosclerosis: role of vitamin E. Biofactors (2003) 19 63 70.
    • (2003) Biofactors , vol.19 , pp. 63-70
    • Kartal, N.O.1    Negis, Y.2    Aytan, N.3
  • 7
    • 0025161633 scopus 로고
    • Ascorbate: The most effective antioxidant in human blood plasma
    • Frei B., Stocker R., England L., Ames B.N. Ascorbate: the most effective antioxidant in human blood plasma. Adv. Exp. Med. Biol. (1990) 264 155 163.
    • (1990) Adv. Exp. Med. Biol. , vol.264 , pp. 155-163
    • Frei, B.1    Stocker, R.2    England, L.3    Ames, B.N.4
  • 8
    • 0014045218 scopus 로고
    • Effect of ascorbic acid on certain blood fat metabolism factors in animals and man
    • PubMed
    • Sokoloff B., Hori M., Saelhof C., McConnell B., Imai T. Effect of ascorbic acid on certain blood fat metabolism factors in animals and man. J. Nutrition. (1967) 91 107 118. PubMed
    • (1967) J. Nutrition. , vol.91 , pp. 107-118
    • Sokoloff, B.1    Hori, M.2    Saelhof, C.3    McConnell, B.4    Imai, T.5
  • 9
    • 0030034465 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodialation in patients with non-insulin dependent diabetes mellitus
    • Ting H.H., Timimi F.K., Boles K.S., Creager S.J., Ganz P., Creager M.A. Vitamin C improves endothelium-dependent vasodialation in patients with non-insulin dependent diabetes mellitus. J. Clin. Invest. (1996) 97 22 28.
    • (1996) J. Clin. Invest. , vol.97 , pp. 22-28
    • Ting, H.H.1    Timimi, F.K.2    Boles, K.S.3    Creager, S.J.4    Ganz, P.5    Creager, M.A.6
  • 10
    • 17844367328 scopus 로고    scopus 로고
    • Small, dense lipoprotein particles and reduced paraoxonase-1 in patients with the metabolic syndrome
    • Garin M.C.B., Kalix B., Morabia A., James R.W. Small, dense lipoprotein particles and reduced paraoxonase-1 in patients with the metabolic syndrome. J. Clin. Endocrinol. Metab. (2005) 90 2264 2269.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 2264-2269
    • Garin, M.C.B.1    Kalix, B.2    Morabia, A.3    James, R.W.4
  • 11
    • 0002557986 scopus 로고
    • Human serum paraoxonase/arylesterase
    • Kalow, W. (. Ed. Pergamon Press, New York, pp.
    • La Du B.N. Human serum paraoxonase/arylesterase, in : Kalow W. (Ed Pharmacogenetics of Drug Metabolism, Pergamon Press, New York, 1992, pp. 51 91.
    • (1992) Pharmacogenetics of Drug Metabolism , pp. 51-91
    • La Du, B.N.1
  • 12
    • 0031661857 scopus 로고    scopus 로고
    • Genetically determined susceptibility to organophosphorous insecticides and nerve agents: Developing a mouse model for the human PON1 polymorphism
    • Furlong C.E., Li W.F., Costa L.G., Richter R.J., Shih D.M., Lusis A.J. Genetically determined susceptibility to organophosphorous insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism. Neurotoxicology (1998) 19 645 650.
    • (1998) Neurotoxicology , vol.19 , pp. 645-650
    • Furlong, C.E.1    Li, W.F.2    Costa, L.G.3    Richter, R.J.4    Shih, D.M.5    Lusis, A.J.6
  • 13
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14,719 initially healthy American women
    • PubMed.
    • Ridker P.M., Buring J.E., Cook N.R., Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14,719 initially healthy American women. Circulation (2003) 107 391 397. PubMed.
    • (2003) Circulation , vol.107 , pp. 391-397
    • Ridker, P.M.1    Buring, J.E.2    Cook, N.R.3    Rifai, N.4
  • 15
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor
    • Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. (1969) 6 24 27.
    • (1969) Ann. Clin. Biochem. , vol.6 , pp. 24-27
    • Trinder, P.1
  • 16
    • 0030036853 scopus 로고    scopus 로고
    • Vascular incorporation of α-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation
    • Keaney J.F. Jr., Guo Y., Cunningham D., Shwaery G.T., Xu A., Vita J.A. Vascular incorporation of α-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation. J. Clin. Invest. (1996) 98 386 394.
    • (1996) J. Clin. Invest. , vol.98 , pp. 386-394
    • Keaney Jr., J.F.1    Guo, Y.2    Cunningham, D.3    Shwaery, G.T.4    Xu, A.5    Vita, J.A.6
  • 17
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh P.N., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. (1988) 175 184 191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, P.N.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 18
    • 0037469232 scopus 로고    scopus 로고
    • Workshop on Inflammatory markers, and Cardiovascular disease: Application to clinical and public health practice. A statement for healthcare professionals from the Centre for Disease Control and Prevention and the American Heart Association
    • PubMed
    • Pearson T.A., Mensah G.A., Alexander R.W. et al. Workshop on Inflammatory markers, and Cardiovascular disease: application to clinical and public health practice. A statement for healthcare professionals from the Centre for Disease Control and Prevention and the American Heart Association. Circulation (2003) 107 499 511. PubMed
    • (2003) Circulation , vol.107 , pp. 499-511
    • Pearson, T.A.1    Mensah, G.A.2    Alexander, R.W.3
  • 19
    • 0345098354 scopus 로고    scopus 로고
    • A novel and simple method for quantification of small dense low-density lipoprotein
    • Hirano T., Ito Y., Saegura H., Yoshino G. A novel and simple method for quantification of small dense low-density lipoprotein. J. Lipid Res. (2003) 44 2193 2201.
    • (2003) J. Lipid Res. , vol.44 , pp. 2193-2201
    • Hirano, T.1    Ito, Y.2    Saegura, H.3    Yoshino, G.4
  • 20
    • 1542343995 scopus 로고    scopus 로고
    • Clinical significance of small dense low-density lipoprotein cholesterol levels determined by the simple precipitation method
    • Hirano T., Ito Y., Koba S., Toyoda M., Ikejiri A., Saegusa H. Clinical significance of small dense low-density lipoprotein cholesterol levels determined by the simple precipitation method. Arterioscler. Thromb. Vasc. Biol. (2004) 24 558 563.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 558-563
    • Hirano, T.1    Ito, Y.2    Koba, S.3    Toyoda, M.4    Ikejiri, A.5    Saegusa, H.6
  • 21
    • 0024550456 scopus 로고
    • Continuous monitoring of in vitro oxidation of human low density lipoprotein
    • Esterbauer H., Striegl G., Puhl H., Rotheneder M. Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic. Res. Commun. (1989) 6 67 75.
    • (1989) Free Radic. Res. Commun. , vol.6 , pp. 67-75
    • Esterbauer, H.1    Striegl, G.2    Puhl, H.3    Rotheneder, M.4
  • 22
    • 0034511340 scopus 로고    scopus 로고
    • Effect of meat replacement by Tofu on CHD risk factors including copper induced LDL oxidation
    • Ashton L.E., Fabien S.D., Madeleine J.B. Effect of meat replacement by Tofu on CHD risk factors including copper induced LDL oxidation. J. Am. College Nutr. (2000) 19 761 767.
    • (2000) J. Am. College Nutr. , vol.19 , pp. 761-767
    • Ashton, L.E.1    Fabien, S.D.2    Madeleine, J.B.3
  • 23
    • 0034297920 scopus 로고    scopus 로고
    • Effect of overexpression of human apo A-1 in C57BL/6 and C57BL/6 apo-E deficient mice on 2 lipoprotein associated enzymes, platelet-activating factor acetylhydrolaseand paraoxonase. Comparison of adenovirus-mediated human apo A-1 gene transfer and human apo A-1 transgenics
    • De Geest B., Stengel D., Landeloos M. et al. Effect of overexpression of human apo A-1 in C57BL/6 and C57BL/6 apo-E deficient mice on 2 lipoprotein associated enzymes, platelet-activating factor acetylhydrolaseand paraoxonase. Comparison of adenovirus-mediated human apo A-1 gene transfer and human apo A-1 transgenics. Arteroiscle. Thromb. Vasc. Biol. (2000) 20 E68 E75.
    • (2000) Arteroiscle. Thromb. Vasc. Biol. , vol.20
    • De Geest, B.1    Stengel, D.2    Landeloos, M.3
  • 24
    • 0024584235 scopus 로고
    • Spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent
    • El-Saddani M., Esterbauer H., Jurgens G.A. Spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent. J. Lipid Res. (1989) 30 627 630.
    • (1989) J. Lipid Res. , vol.30 , pp. 627-630
    • El-Saddani, M.1    Esterbauer, H.2    Jurgens, G.A.3
  • 25
    • 0021288840 scopus 로고
    • Assay for blood plasma or serum
    • Packer, L. (. Ed. Academic Press, Orlando, Florida, pp.
    • Kunio Y. Assay for blood plasma or serum, in : Packer L. (Ed Methods in Enzymology, Academic Press, Orlando, Florida, 1984, pp. 328 331.
    • (1984) Methods in Enzymology , pp. 328-331
    • Kunio, Y.1
  • 26
    • 33845971890 scopus 로고    scopus 로고
    • The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes
    • PubMed
    • Lorenzo C., Williams K., Hunt K.J., Haffner S.M. The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes. Diabetes Care (2007) 30 8 13. PubMed
    • (2007) Diabetes Care , vol.30 , pp. 8-13
    • Lorenzo, C.1    Williams, K.2    Hunt, K.J.3    Haffner, S.M.4
  • 28
    • 33748577187 scopus 로고    scopus 로고
    • DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements
    • Demirbag R., Yilmaz R., Gur M. et al. DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements. Int. J. Clin. Pract. (2006) 60 1187 1193.
    • (2006) Int. J. Clin. Pract. , vol.60 , pp. 1187-1193
    • Demirbag, R.1    Yilmaz, R.2    Gur, M.3
  • 29
    • 33947178519 scopus 로고    scopus 로고
    • Pro-oxidant effect of α-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test - A randomised controlled trial
    • doi
    • Winterbone M.S., Sampson M.J., Saha S., Hughes J.C., Hughes D.A. Pro-oxidant effect of α-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test - a randomised controlled trial. Cardiovasc. Diabetol. (2007) 6 8. doi
    • (2007) Cardiovasc. Diabetol. , vol.6 , pp. 8
    • Winterbone, M.S.1    Sampson, M.J.2    Saha, S.3    Hughes, J.C.4    Hughes, D.A.5
  • 30
    • 38849093119 scopus 로고    scopus 로고
    • Small dense LDL oxidation in hypertensives and diabetics and prediction of metabolic syndrome
    • Nishtha J., Naseem I., Ahmad J. Small dense LDL oxidation in hypertensives and diabetics and prediction of metabolic syndrome. Dia. Met. Syn. Clin. Res. Rev. (2008) 2 21 27.
    • (2008) Dia. Met. Syn. Clin. Res. Rev. , vol.2 , pp. 21-27
    • Nishtha, J.1    Naseem, I.2    Ahmad, J.3
  • 31
    • 58949097015 scopus 로고    scopus 로고
    • Combined vitamins (C and E) and insulin improve oxidative stress and pancreatic and hepatic injury in alloxan diabetic rats
    • Hamden K., Boujbiha M.A., Masmoudi H., Ayadi F.M., Jamoussi K., Elfeki A. Combined vitamins (C and E) and insulin improve oxidative stress and pancreatic and hepatic injury in alloxan diabetic rats. Biomed. Pharmacother. (2009) 63 95 99.
    • (2009) Biomed. Pharmacother. , vol.63 , pp. 95-99
    • Hamden, K.1    Boujbiha, M.A.2    Masmoudi, H.3    Ayadi, F.M.4    Jamoussi, K.5    Elfeki, A.6
  • 32
    • 1842842014 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute, America Heart Association. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute American Heart Association conference on scientific issues related to definition
    • Grundy S.M. Jr., Brewer H.B., Cleeman J.I. Jr., Smith S.C., Lenfant C. National Heart, Lung, and Blood Institute, America Heart Association. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute American Heart Association conference on scientific issues related to definition. Arterioscler. Thromb. Vasc. Biol. (2004) 24 e13 e18.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24
    • Grundy Jr., S.M.1    Brewer, H.B.2    Cleeman Jr., J.I.3    Smith, S.C.4    Lenfant, C.5
  • 33
    • 0037446396 scopus 로고    scopus 로고
    • Are metabolic risk factors one unified syndrome? Modeling the structure of the metabolic syndrome X
    • Shen B.J., Todaro J.F., Niaura R. et al. Are metabolic risk factors one unified syndrome? Modeling the structure of the metabolic syndrome X. Am. J. Epidemiol. (2003) 157 701 711.
    • (2003) Am. J. Epidemiol. , vol.157 , pp. 701-711
    • Shen, B.J.1    Todaro, J.F.2    Niaura, R.3
  • 34
    • 0034659168 scopus 로고    scopus 로고
    • The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide
    • Carr A., Frei B. The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide. Free Radic. Biol. Med. (2000) 28 1806 1814.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1806-1814
    • Carr, A.1    Frei, B.2
  • 35
    • 0042822019 scopus 로고    scopus 로고
    • The metabolic syndrome and antioxidant concentrations: Findings from the Third National Health and Nutrition Examination Survey
    • PubMed
    • Ford E.S., Mokdad A.H., Giles W.H., Brown D.W. The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey. Diabetes (2003) 52 2346 2352. PubMed
    • (2003) Diabetes , vol.52 , pp. 2346-2352
    • Ford, E.S.1    Mokdad, A.H.2    Giles, W.H.3    Brown, D.W.4
  • 37
    • 0029584008 scopus 로고
    • Oxidative stress and the development of diabetic complications- antioxidants and lipid peroxidation in erythrocytes and cell membrane
    • Parthiban A., Vijayalingam S., Shanmugasundaram K.R., Mohan R. Oxidative stress and the development of diabetic complications-antioxidants and lipid peroxidation in erythrocytes and cell membrane. Cell Biol. Int. (1995) 19 987 993.
    • (1995) Cell Biol. Int. , vol.19 , pp. 987-993
    • Parthiban, A.1    Vijayalingam, S.2    Shanmugasundaram, K.R.3    Mohan, R.4
  • 38
    • 0028915679 scopus 로고
    • Prevention of tocopherol mediated peroxidation in ubiquinol-10-free human low density lipoprotein
    • Bowry V.W., Mohr D., Cleary J., Stocker R. Prevention of tocopherol mediated peroxidation in ubiquinol-10-free human low density lipoprotein. J. Biol. Chem. (1995) 270 5756 5763
    • (1995) J. Biol. Chem. , vol.270 , pp. 5756-5763
    • Bowry, V.W.1    Mohr, D.2    Cleary, J.3    Stocker, R.4
  • 39
    • 0030641128 scopus 로고    scopus 로고
    • Requirement for, promotion, or inhibition by α-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation
    • Neuzil J., Thomas S.R., Stocker R. Requirement for, promotion, or inhibition by α-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic. Biol. Med. (1997) 22 57 71.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 57-71
    • Neuzil, J.1    Thomas, S.R.2    Stocker, R.3
  • 40
    • 0001793256 scopus 로고    scopus 로고
    • Vitamin C and redox cycling antioxidants
    • Packer, L., Fuchs, J. (. Eds. Marcel Dekker Inc, New York, pp.
    • Packer L. Vitamin C and redox cycling antioxidants, in : Packer L., Fuchs J. (Eds Vitamin C in Health and Disease, Marcel Dekker Inc, New York, 1997, pp. 95 121.
    • (1997) Vitamin C in Health and Disease , pp. 95-121
    • Packer, L.1


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