A practical synthesis of (2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-d-ribono-γ-lactone

Tetrahedron Asymmetry

Volumn 20, Issue 3, 2009, Pages 305-312

  Zhang, Pingsheng ^a   Iding, Hans ^b   Cedilote, Miall ^a   Brunner, Stephan ^b   Williamson, Thomas ^a   Cleary, Thomas P ^a  

^a Roche Carolina   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DI O BENZOYL 2 FLUORO 2 C METHYL DEXTRO RIBONO GAMMA LACTONE; ETHYL 4,5 ISOPROPYLIDENE 2 FLUORO 3 HYDROXY 2 METHYLVALERATE; ETHYL 4,5 ISOPROPYLIDENE 2 FLUORO 3 KETO 2 METHYLVALERATE; ETHYL 4,5 O ISOPROPYLIDENE 2 FLUORO 3 HYDROXY 2 METHYLVALERATE; LACTONE DERIVATIVE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ALDOL REACTION; ARTICLE; HYDROLYSIS; ISOMER; PRIORITY JOURNAL; PURIFICATION; SYNTHESIS;

EID: 62849109318     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2009.02.006     Document Type: Article

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39. Prepared following the literature procedure in Ref. 12c.
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51. CALB was a technical solution from BioCatalytics, Cat# SO L-101, Lot# CN02100.