Eradication of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit: Which measures for which success?

American Journal of Infection Control

Volumn 37, Issue 3, 2009, Pages 195-200

  Lepelletier, Didier ^a,b   Corvec, Stéphane ^a,b   Caillon, Jocelyne ^a,b   Reynaud, Alain ^a,b   Rozé, Jean Christophe ^a   Gras Leguen, Christèle ^a,b  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PSEUDOMONIC ACID;

ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM ISOLATION; CLINICAL ARTICLE; FEMALE; HEALTH CARE PERSONNEL; HUMAN; HYGIENE; INFECTION CONTROL; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NEWBORN; NEWBORN INTENSIVE CARE; OINTMENT; STAFF TRAINING;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; DISEASE OUTBREAKS; EDUCATION; FRANCE; HANDWASHING; HUMANS; INFANT, NEWBORN; INFECTION CONTROL; INTENSIVE CARE UNITS, NEONATAL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MUPIROCIN; PATIENT ISOLATION; SENTINEL SURVEILLANCE; STAPHYLOCOCCAL INFECTIONS;

EID: 62849102880     PISSN: 01966553     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajic.2008.09.024     Document Type: Article

References (20)

1. Saiman L., Cronquist A., Wu F., Zhou J., Rubenstein D., Eisner W., et al. An outbreak of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit. Infect Control Hosp Epidemiol 24 (2003) 317-321
2. Khoury J., Jones M., Grim A., Dunne W.M., and Fraser V. Eradication of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit by active surveillance and aggressive infection control measures. Infect Control Hosp Epidemiol 26 (2005) 616-621
3. Andersen B.M., Lindemann R., Bergh K., Nesheim B.I., Syversen G., Solheim N., et al. Spread of methicillin-resistant Staphylococcus aureus in a neonatal intensive unit associated with understaffing, overcrowding and mixing of patients. J Hosp Infect 50 (2002) 18-24
4. Haley R.W., Cushion N.B., Tenover F.C., Bannerman T.L., Dryer D., Ross J., et al. Eradication of endemic methicillin-resistant Staphylococcus aureus infections from a neonatal intensive care unit. J Infect Dis 17 (1995) 614-624
5. Back N.A., Linnemann C.C., Staneck J.L., and Kotagal U.R. Control of methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit: Use of intensive microbiologic surveillance and mupirocin. Infect Control Hosp Epidemiol 17 (1996) 227-231
6. Tenover F.C., Arbeit R.D., Goering R.V., Mickelsen P.A., Murray B.E., Persing D.H., et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing. J Clin Microbiol 33 (1995) 2233-2239
7. McDonald J.R., Carriker C.M., Pien B.C., Trinh J.V., Engemann J.J., Harrell L.J., et al. Methicillin-resistant Staphylococcus aureus outbreak in an intensive care nursery: Potential for interinstitutional spread. Pediatr Infect Dis 26 (2007) 678-683
8. Kampf G., and Kramer A. Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs. Clin Microbiol Rev 17 (2004) 863-869
9. Boyce J.M., Havill N.L., Otter J.A., and Adams N.M. Widespread environmental contamination associated with patients with diarrhea and methicillin-resistant Staphylococcus aureus colonization of the gastrointestinal tract. Infect Control Hosp Epidemiol 28 (2007) 1142-1147
10. Wilson R.D., Huang S.J., and McLean A.S. The correlation between airborne methicillin-resistant Staphylococcus aureus with the presence of MRSA-colonized patients in a general intensive care unit. Anaesth Intensive Care 32 (2004) 202-209
11. Dancer S.J. Importance of the environment in methicillin-resistant Staphylococcus aureus acquisition: The case for hospital cleaning. Lancet Infect Dis 8 (2008) 101-113
12. Dancer S.J., Coyne M., Speekenbrink A., Samavedam S., Kennedy J., and Wallace P.G. MRSA acquisition in an intensive care unit. Am J Infect Control 34 (2006) 10-17
13. Boyce J.M. Environmental contamination makes an important contribution to hospital infection. J Hosp Infect 65 Suppl 2 (2007) 50-54
14. Beggs C.B., Noakes C.J., Shepherd S.J., Kerr K.G., Sleigh P.A., and Banfield K. The influence of nurse cohorting on hand hygiene effectiveness. Am J Infect Control 34 (2006) 621-626
15. Maragakis L.L., Winkler A., Tucker M.G., Cosgrove S.E., Ross T., Lawson E., et al. Outbreak of multidrug-resistant Serratia marcescens infection in a neonatal intensive care unit. Infect Control Hosp Epidemiol 29 (2008) 418-423
16. Campbell J.R., Zaccaria E., Mason Jr. E.O., and Baker C.J. Epidemiological analysis defining concurrent outbreaks of Serratia marcescens and methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit. Infect Control Hosp Epidemiol 19 (1998) 924-928
17. Gerber S.I., Jones R.C., Scott M.V., Price J.S., Dworkin M.S., Filippell M.B., et al. Management of outbreaks of methicillin-resistant Staphylococcus aureus infection in the neonatal intensive care unit: A consensus statement. Infect Control Hosp Epidemiol 27 (2006) 139-145
18. Hitomi S., Kubota M., Mori N., Baba S., Yano H., Okuzumi K., et al. Control of a methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit by unselective use of nasal mupirocin ointment. J Hosp Infect 46 (2000) 123-129
19. Bertin M.L., Vinski J., Schmitt S., Sabella C., Danziger-Isakov L., McHugh M., et al. Outbreak of methicillin-resistant Staphylococcus aureus colonization and infection in a neonatal intensive care unit epidemiologically linked to a healthcare worker with chronic otitis. Infect Control Hosp Epidemiol 27 (2006) 581-585
20. Kim Y.H., Chang S.S., Kim Y.S., Kim E.A., Yun S.C., Kim K.S., et al. Clinical outcomes in methicillin-resistant Staphylococcus aureus-colonized neonates in the neonatal intensive care unit. Neonatology 91 (2007) 241-247