Melatonin reduces cortisol response to ACTH in humans;La melatonina reduce la respuesta de cortisol al ACTH en humanos

Revista Medica de Chile

Volumn 136, Issue 11, 2008, Pages 1390-1397

  Campino, Carmen ^a   Valenzuela, Francisco ^b   Arteaga, Eugenio ^a   Torres Farfán, Claudia ^b   Trucco, Cristián ^a   Velasco, Alfredo ^a   Guzmán, Sergio ^a   Serón Ferré, María ^b,c  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSIDAD DE TARAPACÁ   (Chile)

Author keywords

Adrenocorticotropic hormone; Hydrocortisone; Melatonin

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MESSENGER RNA;

ADRENAL GLAND; ADULT; ARTICLE; BIOSYNTHESIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; IMMUNOASSAY; MALE; RANDOMIZED CONTROLLED TRIAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION; TIME;

ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ADULT; CROSS-OVER STUDIES; DEXAMETHASONE; DOUBLE-BLIND METHOD; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; IMMUNOASSAY; MALE; MELATONIN; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; YOUNG ADULT;

EID: 62849102055     PISSN: 00349887     EISSN: 07176163     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Brzezinski A. Melatonin in humans. N Engl J Med 1997; 336: 186-95.
2. Arendt J, Skene DJ. Melatonin as a chronobiotic. Sleep Med Rev 2005; 9: 25-39.
3. Ekmekcioglu C. Melatonin receptor in human: biological role and clinical relevance. Biomed Pharmacother 2006; 60: 97-108.
4. Lanoix D, Ouellette R, Vaillancourt C. Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. Hum Reprod 2006; 21: 1981-9.
5. Woo MMM, Tai CJ, Kang SK, Nathwani PS, Pang SFP, Leung PCK. Direct action of melatonin in human granulosa-luteal cells. J Clin Endocrinol Metab 2001; 86: 4789-97.
6. Valenti S, Giusti M. Melatonin participates in the control of testosterone secretion from rat testis: an overview of our experience. Ann N Y Acad Sci 2002; 966: 284-9.
7. Frungieri MB, Mayerhofer A, Zitta K, Pignataro OP, Calandra RS, González-Calvar SI. Direct effect of melatonin on Syrian hamster testes: Melatonin subtype 1a receptors, inhibition of androgen production, and interaction with the local corticotropin-realising hormone system. Endocrinology 2005; 146: 1541-52.
8. Richter HG, Torres-Farfán C, García-Sesnich J, Abarzúa-Catalán L, Henríquez MG, Alvarez-Felmer M et al. Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland. Endocrinology 2008; 149: 995-1003.
9. Torres-Farfán C, Richter HG, Germain A, Valenzuela G, Campino C, Rojas-García P et al. Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland. J Physiol 2004; 554: 841-56.
10. Torres-Farfán C, Richter HG, Rojas-García P, Vergara M, Forcelledo ML, Valladares LE et al. mt1 Melatonin receptor in the primate adrenal gland: inhibition of adrenocorticotropin-stimulated cortisol production by melatonin. J Clin Endocrinol and Metab 2003; 88: 450-8.
11. Valenzuela FJ, Torres-Farfán C, Richter HG, Méndez N, Campino C, Torrealba F et al. Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: is the adrenal a peripheral clock responsive to melatonin? Endocrinology 2008; 149: 1454-61.
12. Weibel L, Brandenberger G. The start of the quiescent period of cortisol remains phase locked to the melatonin onset despite circadian phase alterations in humans working the night schedule. Neurosci Lett 2002; 318: 89-92.
13. Leproult R, Colecchia EF, L'Hermite-Baleriaux M, Van Cauter E. Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels. J Clin Endocrinol Metab 2001; 86: 151-7.
14. Scheer FAJL, Buijs RM. Light affects morning salivary cortisol in humans. J Clin Endocrinol Metab 1999; 84: 3395-8.
15. Waldhauser F, Lieberman HR, Lynch HJ, Waldhauser M, Herkner K, Frisch H et al. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol. Neuroendocrinology 1987; 46: 125-30.
16. Cagnacci A, Soldani R, Yen SSC. Melatonin enhances cortisol levels in aged but not young women. Eur J Endocrinol 1995; 133: 691-5.
17. Terzolo M, Piovesan A, Osella G, Torta M, Bunita T, Paccotti P et al. Exogenous melatonin enhances the TRH-induced prolactin release in normally cycling women: a sex-specific effect. Gynecol Endocrinol 1991; 5: 83-94.
18. Paccotti P, Terzolo M, Piovesan M, Torta M, Vignani A, Angeli A. Effects of endogenous melatonin on human pituitary and adrenal secretions. Hormonal responses to specific stimuli after acute administration of different doses at two opposite circadian stages in men. Chronobiologia 1988; 15: 279-88.
19. Perras B, Özcan S, Fehm HL, Born J. Melatonin does not inhibit hypothalamic-pituitary-adrenal activity in waking young men. J Neuroendocrinol 2005; 17: 811-6.
20. Bornstein SR, Chrousos GP. Adrenocorticotropin (ACTH) and Non-ACTH-mediated regulation of the adrenal cortex: Neural and Immune Inputs. J Clin Endocrinol Metab 1999; 84: 1729-36.
21. Drew JE, Williams LM, Hannah LT, Barrett P, Abramovich DR. Melatonin receptors in the human fetal kidney: 2-[125I]iodomelatonin binding sites correlated with expression of Mel1a and Mel1b receptor genes. J Endocrinol 1998; 156: 261-7.
22. Park YJ, Park KS, Kim JH, Shin CS, Kim SY, Lee HK. Reproducibility of the cortisol response to stimulation with the low dose (1microg) of ACTH. Clin Endocrinol 1999; 51: 153-8.
23. Torres-Farfán C, Valenzuela FJ, Ebensperger R, Méndez N, Campino C, Richter HG et al. Circadian cortisol secretion and circadian adrenal responses to ACTH are maintained in dexamethasone suppressed capuchin monkeys (Cebus apella). Am J Primatol 2008; 70: 93-100.
24. Engeland WC, Arnhold MM. Neural circuitry in the regulation of adrenal corticosterone rhythmicity. Endocrine 2005; 28: 325-32.
25. Torres-Farfán C, Rocco V, Monsó C, Valenzuela FJ, Campino C, Germain A et al. Maternal melatonin effects on clock gene expression in a nonhuman primate fetus. Endocrinology 2006; 147: 4618-26.
26. Torres-Farfán C, Valenzuela FJ, Germain AM, Viale ML, Campino C, Torrealba F et al. Maternal melatonin stimulates growth and prevents maturation of the capuchin monkey fetal adrenal gland. J Pineal Res 2006; 41: 58-66.
27. Sufi SB, Donaldson A, Jeffcoate SL. Programme for the provision of matched assay reagents for the radioimmunoassay of hormones in reproductive physiology. Methods manual 1993. London: WHO.
28. nd ed, Ed. SAS Institute 2006; 159-204.
29. Reppert SM, Weaver DR, Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 1994; 13: 1177-85.
30. Fischer S, Smolnik R, Herms M, Born J, Fehm H. Melatonin acutely improves the neuroendocrine architecture of sleep in blind individuals. J Clin Endocrinol Metab 2003; 88: 5315-20.
31. Fardella CE, Mosso L, Gómez-Sánchez C, Cortés P, Soto J, Gómez L et al. Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology. J Clin Endocrinol Metab 2000; 85: 1863-7.
32. Campusano C, Brusco F, Campino C, Rodríguez L, Arteaga E. Comparación de distintos métodos para evaluar la función androgénica en el adulto mayor. Rev Méd Chile 2006; 134: 1123-8.
33. Van Cauter E, L'Hermite M, Copinschi G, Refetoff S, Desir D, Robyn C. Quantitative analysis of spontaneous variations of plasma prolactin in normal man. Am J Physiol 1981; 241: E355-E363.
34. Waldstreicher J, Duffy JF, Brown EN, Rogacz S, Allan JS, Czeisler CA. Gender differences in the temporal organization of prolactin (PRL) secretion: evidence for a sleep-independent circadian rhythm of circulating PRL levels- a clinical research center study. J Clin Endocrinol Metab 1996; 81: 1483-7.
35. Zisapel N. Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting. Cell Mol Neurobiol 2001; 21: 605-16.