Vibrio vulnificus cytolysin induces apoptosis in HUVEC, SGC-7901 and SMMC-7721 cells via caspase-9/3-dependent pathway

Microbial Pathogenesis

Volumn 46, Issue 4, 2009, Pages 194-200

  Zhao, Jin fang ^a,b   Sun, Ai hua ^c   Ruan, Ping ^d   Zhao, Xu hong ^b   Lu, Miao quan ^b   Yan, Jie ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d SHAOXING UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; HUVEC; SGC 7901; SMMC 7721; Vibrio vulnificus cytolysin

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOLYSIN; LACTATE DEHYDROGENASE; POTASSIUM CHANNEL;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VIBRIO VULNIFICUS;

APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; CYTOPLASM; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HEPATOCYTES; HUMANS; L-LACTATE DEHYDROGENASE; PERFORIN; POTASSIUM; VIBRIO VULNIFICUS;

MAMMALIA; VIBRIO VULNIFICUS;

EID: 62749202615     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2008.12.005     Document Type: Article

References (37)

1. DePaola A., Capers G.M., and Alexander D. Densities of Vibrio vulnificus in the intestines of fish from the U.S. Gulf Coast. Appl Environ Microbiol 60 (1994) 984-988
2. Buchrieser C., Gangar V.V., Murphree R.L., Tamplin M.L., and Kaspar C.W. Multiple Vibrio vulnificus strains in oysters as demonstrated by clamped homogeneous electric field gel electrophoresis. Appl Environ Microbiol 61 (1995) 1163-1168
3. Arias C.R., Pujalte M.J., Garay E., and Aznar R. Influence of water temperature and salinity on Vibrio vulnificus in Northern Gulf and Atlantic Coast oysters (Crassostrea virginica). Appl Environ Microbiol 64 (1998) 1459-1465
4. Blake P.A., Merson M.H., Weaver R.E., Hollis D.G., and Heublein P.C. Disease caused by a marine Vibrio. Clinical characteristics and epidemiology. N Engl J Med 300 (1979) 1-5
5. Gray L.D., and Kreger A.S. Purification and characterization of an extracellular cytolysin produced by Vibrio vulnificus. Infect Immun 48 (1985) 62-72
6. Park J.W., Ma S.N., Song E.S., Song C.H., Chae M.R., Park B.H., et al. Pulmonary damage by Vibrio vulnificus Cytolysin. Infect Immun 64 (1996) 2873-2876
7. Linkous D.A., and Oliver J.D. Pathogenesis of Vibrio vulnificus. FEMS Microbiol Lett 174 (1999) 207-214
8. Gulig P.A., Bourdage K.L., and Starks A.M. Molecular pathogenesis of Vibrio vulnificus. J Microbiol 43 (2005) 118-131
9. Lee BC, Choi SH, Kim TS. Vibrio vulnificus RTX toxin plays an important role in the apoptotic death of human intestinal epithelial cells exposed to Vibrio vulnificus. Microbes Infect, in press.
10. Lee B.C., Lee J.H., Kim M.W., Kim B.S., Oh M.H., Kim K.S., et al. Vibrio vulnificus rtxE is important for virulence, and its expression is induced by exposure to host cells. Infect Immun 76 (2008) 1509-1517
11. Kim Y.R., Lee S.E., Kook H., Yeom J.A., Na H.S., Kim S.Y., et al. Vibrio vulnificus RTX toxin kills host cells only after contact of the bacteria with host cells. Cell Microbiol 10 (2008) 848-862
12. Kim B.S., and Kim J.S. Vibrio vulnificus cytolysin induces hyperadhesiveness of pulmonary endothelial cells for neutrophils through endothelial P-selectin: a mechanism for pulmonary damage by Vibrio vulnificus cytolysin. Exp Mol Med 34 (2002) 308-312
13. Miyoshi S., Oh E.G., Hirata K., and Shinoda S. Exocellular toxic factors produced by Vibrio vulnificus. J Toxicol Toxin Rev 12 (1993) 253-288
14. Kim H.R., Rho H.W., Jeong M.H., Park J.W., Kim J.S., Park B.H., et al. Hemolytic mechanism of cytolysin produced from V. vulnificus. Life Sci 53 (1993) 571-578
15. 2+ on the hemolysis caused by Vibrio vulnificus cytolysin. Biochim Biophys Acta 1194 (1994) 166-170
16. Yamanaka, Sugiyama K., Furuta H., Miyoshi S., and Shinoda S. Cytolytic action of Vibrio vulnificus haemolysin on mast cells from rat peritoneal cavity. J Med Microbiol 32 (1990) 39-43
17. Kim J.S., Chae M.R., Chang K., Park K.H., Rho H.W., Park B.H., et al. Cytotoxicity of Vibrio vulnificus cytolysin on rat peritoneal mast cells. Microbiol Immunol 42 (1998) 837-843
18. Kim J.S. Cytotoxicity of Vibrio vulnificus cytolysin on pulmonary endothelial cells. Exp Biol Med 29 (1997) 117-121
19. Kang M.K., Jhee E.C., Koo B.S., Yang J.Y., Park B.H., Kim J.S., et al. Induction of nitric oxide synthase expression by Vibrio vulnificus cytolysin. Biochem Biophys Res Commun 290 (2002) 1090-1095
20. Rho H.W., Choi M.J., Lee J.N., Park J.W., Kim J.S., Park B.H., et al. Cytotoxic mechanism of Vibrio vulnificus cytolysin in CPAE cells. Life Sci 70 (2002) 1923-1934
21. Kwon K.B., Yang J.Y., Ryu D.G., Rho H.W., Kim J.S., Park J.W., et al. Vibrio vulnificus cytolysin induces superoxide anion-initiated apoptotic signaling pathway in human ECV304 cells. J Biol Chem 276 (2001) 47518-47523
22. Drexler H.G., Quentmerier H., and Driks W.G. Bladder carcinoma cell line ECV-304 is not a model system for endothelial cells. In Vitro Cell Dev Biol 38 (2002) 185-186
23. Park K.H., Yang H.B., Kim H.G., Lee Y.R., Hur H., Kim J.S., et al. Low density lipoprotein inactivates vibrio vulnificus cytolysin through the oligomerization of toxin monomer. Med Microbiol Immunol 194 (2005) 137-141
24. Tweten R.K. Cholesterol-dependent Cytolysins, a family of Versatile pore-forming toxins. Infect Immun 73 (2005) 6199-6209
25. Bhakdi S., and Tranum-Jensen J. Damage to cell membranes by pore-forming bacterial cytolysins. Prog Allergy 40 (1988) 1-43
26. Cohen J.J. Apoptosis. Immunol Today 14 (1993) 126-130
27. Gonzalez M.R., Bischofberger M., Pernot L., van der Goot F.G., and Frêche B. Bacterial pore-forming toxins: the (w)hole story?. Cell Mol Life Sci 65 (2008) 493-507
28. Nelson K.L., Brodsky R.A., and Buckley J.T. Channels formed by subnanomolar concentrations of the toxin aerolysin trigger apoptosis of T lymphomas. Cell Microbiol 1 (1999) 69-74
29. Jonas D., Walev I., Berger T., Liebetrau M., Palmer M., and Bhakdi S. Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation. Infect Immun 62 (1994) 1304-1312
30. Kook H., Rhee J.H., Lee S.E., Kang S.Y., Chung S.S., Cho K.W., et al. Activation of particulate guanylyl cyclase by Vibrio vulnificus hemolysin. Eur J Pharmacol 365 (1999) 267-272
31. Yu H.N., Lee Y.R., Park K.H., Rah S.Y., Noh E.M., Song E.K., et al. Membrane cholesterol is required for activity of Vibrio vulnificus cytolysin. Arch Microbiol 187 (2007) 467-473
32. Wei Y.B., Fan T.J., and Yu M.M. Inhibitor of apoptosis proteins and apoptosis. Acta Biochim Biophys Sin 40 (2008) 278-288
33. Pinkoski M.J., Brunner T., Green D.R., and Lin T. Fas and Fas ligand in gut and liver. Am J Physiol Gastrointest Liver Physiol 278 (2000) G354-G366
34. Garrido C., Galluzzi L., Brunet M., Puig P.E., Didelot C., and Kroemer G. Mechanisms of cytochrome c release from mitochondria. Cell Death and Differ 13 (2006) 1423-1433
35. Bernheimer A.W., and Schwartz L.L. Isolation and composition of staphylococcal alpha-toxin. J Gen Microbiol 30 (1963) 455-468
36. Oez S., Platzer E., and Welte K. A quantitative colorimetric method to evaluate the functional state of human polymorphonuclear leukocytes. Blut 60 (1990) 97-102
37. Shukla A., Sharma S., and Guptasarma P. Confocal spectrofluorimetric evidence for the hetero-aggregation of sequence-scrambled forms of two model all-beta sheet proteins. Int J Biol Macromol 41 (2007) 650-654