Methotrexate-related leukoencephalopathy without radiation therapy: Distribution of brain lesions and pathological heterogeneity on two autopsy cases

Neuropathology

Volumn 29, Issue 2, 2009, Pages 105-115

  Matsubayashi, Jun ^a   Tsuchiya, Kuniaki ^b   Matsunaga, Takashi ^c   Mukai, Kiyoshi ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN MATSUZAWA HOSPITAL   (Japan)

^c ASAHI GENERAL HOSPITAL   (Japan)

Author keywords

Axonal change; Demyelination; Heterogeneity; Leukoencephalopathy; Methotrexate

Indexed keywords

ARABINOSIDE; CYTARABINE; CYTOSINE; DAUNORUBICIN; DOXORUBICIN; FLUOROURACIL; MERCAPTOPURINE; METHOTREXATE; MITOMYCIN; MITOXANTRONE; PREDNISOLONE;

ACUTE GRANULOCYTIC LEUKEMIA; ADENOCARCINOMA; ADULT; ANEMIA; ARTICLE; ASPIRATION PNEUMONIA; ATAXIA; AUTOPSY; BRAIN NECROSIS; BULBAR PARALYSIS; CARCINOMATOUS MENINGITIS; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CONVULSION; DELIRIUM; DEMYELINATING DISEASE; DIPLOPIA; DISORIENTATION; DISSEMINATED NECROTIZING LEUKOENCEPHALOPATHY; DYSPNEA; FACIAL NERVE PARALYSIS; FRONTAL LOBE; HEARING IMPAIRMENT; HEMISPHERE; HISTOPATHOLOGY; HUMAN; LEUKOCYTOSIS; LEUKOENCEPHALOPATHY; LUNG EDEMA; MALE; OCCIPITAL LOBE; OPHTHALMOPLEGIA; PRIORITY JOURNAL; REMISSION; RESPIRATORY FAILURE; SPHEROID CELL; TEMPORAL LOBE; THROMBOCYTOPENIA; WHITE MATTER;

ANTINEOPLASTIC AGENTS; BRAIN; BRAIN DISEASES; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; NERVE FIBERS, MYELINATED;

EID: 62749182268     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2008.00945.x     Document Type: Article

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