Development and characterization of a novel host cell DNA assay using ultra-sensitive fluorescent nucleic acid stain "PicoGreen"

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 4, 2009, Pages 997-1002

  Ikeda, Yosuke ^a   Iwakiri, Shoji ^a   Yoshimori, Takayuki ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

DNA assay; High throughput technology; Host cell DNA; Impurity clearance; PicoGreen

Indexed keywords

CELL DNA; DNA FRAGMENT; DODECYL SULFATE SODIUM; DOUBLE STRANDED DNA; FLUORESCENT DYE; PROTEINASE K;

AGAR GEL ELECTROPHORESIS; ARTICLE; CELL CULTURE; DNA DETERMINATION; DNA EXTRACTION; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; PROTEIN DEGRADATION; SENSITIVITY AND SPECIFICITY; SUPERNATANT;

ANIMALS; CHO CELLS; CHROMATOGRAPHY, AFFINITY; CRICETINAE; CRICETULUS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASE K; FLUORESCENT DYES; HUMANS; LINEAR MODELS; ORGANIC CHEMICALS; PROTEIN HYDROLYSATES; RECOMBINANT PROTEINS;

EID: 62749151585     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.01.022     Document Type: Article

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