Simultaneous determination of three anticon-vulsants using hydrophilic interaction LC-MS

Journal of Separation Science

Volumn 32, Issue 2, 2009, Pages 238-243

  Oertel, Reinhard ^a   Arenz, Norman ^a   Pietsch, Jörg ^a   Kiroh, Wilhelm ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Anticonvulsants; HILIC; Hydrophilic interaction; LC MS MS

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; PATIENT MONITORING;

ANALYTES; ANTICONVULSANTS; AUTOMATED METHODS; BIOLOGICAL SAMPLES; COLUMN TEMPERATURES; HILIC; HILIC-MS; HUMAN SERUM; HYDROPHILIC INTERACTION; HYDROPHILIC INTERACTION CHROMATOGRAPHIES; LC-MS-MS; MATRIXES; MOBILE PHASE; MULTIPLE-REACTION MONITORING MODES; PROTEIN PRECIPITATIONS; SIMULTANEOUS DETERMINATIONS; STANDARD CURVES; THERAPEUTIC DRUG MONITORING; VIGABATRIN;

HYDROPHILICITY;

ANTICONVULSIVE AGENT; GABAPENTIN; PREGABALIN; VIGABATRIN; 4 AMINOBUTYRIC ACID; AMINE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; DRUG DERIVATIVE; WATER;

ARTICLE; AUTOMATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG MONITORING; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; TEMPERATURE SENSITIVITY; CALIBRATION; CHEMISTRY; METHODOLOGY; SOLUTION AND SOLUBILITY; TEMPERATURE;

AMINES; ANTICONVULSANTS; CALIBRATION; CHROMATOGRAPHY, LIQUID; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; SOLUTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TEMPERATURE; VIGABATRIN; WATER;

EID: 62749130197     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200800461     Document Type: Article

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