Investigating the genetic role of aquaporin4 gene in migraine

Journal of Headache and Pain

Volumn 10, Issue 2, 2009, Pages 111-114

  Rubino, Elisa ^a   Rainero, I ^a   Vaula, G ^a   Crasto, F ^a   Gravante, E ^a   Negro, E ^a   Brega, F ^a   Gallone, S ^a   Pinessi, L ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Aquaporin4; Genetic association study; Migraine with aura; Migraine without aura

Indexed keywords

AQUAPORIN 4;

ADULT; ALLELE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; MIGRAINE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AQUAPORIN 4; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; ITALY; MALE; MIDDLE AGED; MIGRAINE DISORDERS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 62749102526     PISSN: 11292369     EISSN: 11292377     Source Type: Journal    
DOI: 10.1007/s10194-009-0100-z     Document Type: Article

References (34)

1. Ferrari MD (1998) Migraine. Lancet 51:1043-1051
2. Scher AI, Stewart WF, Liberman J et al (1998) Prevalence of frequent headache in a population sample. Headache 38:497-506
3. Stewart WF, Lipton RB, Celentano DD et al (1992) Prevalence of migraine headache in the United States: Relation to age, income, race, and other sociodemographic factors. JAMA 267:64-69
4. Burton WN, Conti DJ, Chen CY et al (2002) The economic burden of lost productivity due to migraine headache: A specific worksite analysis. J Occup Environ Med 44:523-529
5. Russell MB, Iselius L, Olesen J (1996) Migraine without aura and migraine with aura are inherited disorders. Cephalalgia 16:305-309
6. Estevez M, Gardner KL (2004) Update on the genetics of migraine. Hum Genet 114:225-235
7. Wessman M, Terwindt GM, Kaunisto MA, Palotie A, Ophoff RA (2007) Migraine: A complex genetic disorder. Lancet Neurol 6:521-532
8. Bolay H, Reuter U, Dunn AK et al (2002) Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med 8:136-142
9. Alvarez-Cermeno J, Gobernado JM, Gimeno A (1986) Transient blood-brain barrier (BBB) damage in migraine. Neurology 26:437
10. Dreier JP, Jurkat-Rott K, Petzold GC et al (2005) Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II. Neurology 64:2145-2147
11. Leira R, Sobrino T, Rodriguez-Yanez M et al (2007) Mmp-9 immunoreactivity in acute migraine. Headache 47:698-702
12. Nielsen S, Nagelhus EA, Amiry-Moghaddam M et al (1997) Specialized membrane domains for water transport in glial cells: High-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 17:171-180
13. Amiry-Moghaddam M, Otsuka T, Hurn PD et al (2003) An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci USA 100:2106-2111
14. Abbott NJ, Ronnback L, Hansson E (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7:41-53
15. + siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. Glia 26:47-54
16. Zeng XN, Sun XL, Gao L et al (2006) Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes. Mol Cell Neurosci 34:34-39
17. Lennon VA, Kryzer TJ, Pittock SJ et al (2005) IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 202:473-477
18. Binder DK, Yao X, Zador Z et al (2006) Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia 53:631-636
19. Griesdale DE, Honey CR (2004) Aquaporins and brain edema. Surg Neurol 61:418-421
20. Bjornsson A, Gudmundsson G, Gudfinnsson E et al (2003) Localization of a gene for migraine without aura to chromosome 4q21. Am J Hum Genet 73:986-993
21. Lea RA, Nyholt DR, Curtain RP et al (2005) A genome-wide scan provides evidence for loci influencing a severe heritable form of common migraine. Neurogenetics 6:67-72
22. Headache Classification Subcommittee of the International Headache Society (2004) The international classification of headache disorders, 2nd edn. Cephalalgia 24(Suppl 1):1-151
23. Lu M, Lee MD, Smith BL et al (1996) The human AQP4 gene: Definition of the locus encoding two water channel polypeptides in brain. Proc Natl Acad Sci USA 93:10908-10912
24. Bird TD, Jarvik GP, Wood NW (2001) Genetic association studies: Genes in search of diseases. Neurology 57:1153-1154
25. Sorani MD, Zador Z, Hurowitz E et al (2008) Novel variants in human aquaporin-4 reduce cellular water permeability. Hum Mol Genet 17:2379-2389
26. Muratake T, Fukui N, Kaneko N et al (2005) Linkage disequilibrium in aquaporin 4 gene and association study with schizophrenia. Psychiatry Clin Neurosci 59:595-598
27. Papadopoulos MC, Verkman AS (2005) Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem 280:13906-13912
28. Bloch O, Papadopoulos MC, Manley GT et al (2005) Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. J Neurochem 95:254-262
29. Saadoun S, Papadopoulos MC, Davies DC et al (2002) Aquaporin-4 expression is increased in oedematous human brain tumours. J Neurol Neurosurg Psychiatry 72:262-265
30. Benarroch EE (2007) Aquaporin-4, homeostasis, and neurologic disease. Neurology 69:2266-2268
31. Kleffner I, Bungeroth M, Schiffbauer H et al (2008) The role of aquaporin-4 polymorphisms in the development of brain edema after middle cerebral artery occlusion. Stroke 39:1333-1335
32. Manley GT, Fujimura M, Ma T et al (2000) Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med 6:159-163
33. Verkman AS, Binder DK, Bloch O et al (2006) Three distinct roles of aquaporin-4 in brain function revealed by knockout mice. Biochim Biophys Acta 1758:1085-1093
34. Papadopoulos MC, Verkman AS (2008) Potential utility of aquaporin modulators for therapy of brain disorders. Prog Brain Res 170:589-601