A transient diffusion model of the cornea for the assessment of oxygen diffusivity and consumption

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 3, 2009, Pages 1076-1080

  Larrea, Xabier ^a   Büchler, Philippe ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; CORNEA; LACRIMAL FLUID; MATHEMATICAL MODEL; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN TENSION; PRIORITY JOURNAL; CONTACT LENS; DIFFUSION; HUMAN; METABOLISM; PHYSIOLOGY; THEORETICAL MODEL; TIME; TRANSPORT AT THE CELLULAR LEVEL;

OXYGEN;

BIOLOGICAL TRANSPORT; CONTACT LENSES; CORNEA; DIFFUSION; HUMANS; MODELS, THEORETICAL; OXYGEN; OXYGEN CONSUMPTION; TEARS; TIME FACTORS;

EID: 62649155866     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2479     Document Type: Article

References (20)

1. Klyce SD. Stromal lactate accumulation can account for corneal oedema osmotically following epithelial hypoxia in the rabbit. J Physiol. 1981;321:49-64.
2. Klyce SD, Bauerman RW. Structure and function of the cornea. In: Kaufman HE, ed. The Cornea. 2nd ed. London: Butterworth & Heinemann; 1998:3-50.
3. Bonanno JA, Stickel T, Nguyen T, et al. Estimation of human corneal oxygen consumption by noninvasive measurement of tear oxygen tension while wearing hydrogel lenses. Invest Ophthalmol Vis Sci. 2002;43:371-376.
4. Fatt I. New physiological paradigms to assess the effect of lens oxygen transmissibility on corneal health. CLAO J. 1996;22:25-29.
5. Hill RM, Fatt I. Oxygen measurements under a contact lens. Am J Optom. 1964;41:382-387.
6. Hill RM, Fink B, Smith B, et al. Oxygen shortfall associated with different Dk values. Br J Optom Dispensing. 1994;2:403-405.
7. Fatt I, Bieber MT. The steady-state distribution of oxygen and carbon dioxide in the in vivo cornea, I: the open eye in air and the closed eye. Exp Eye Res. 1968;7:413.
8. Freeman RD. Oxygen consumption by the component layers of the cornea. J Physiol. 1972;225:15-32.
9. Freeman RD, Fatt I. Oxygen permeability of the limiting layers of the cornea. Biophys J. 1972;12:237-247.
10. Fatt I, Freeman RD, Lin D. Oxygen tension distributions in the cornea: a re-examination. Exp Eye Res. 1974;18:357-365.
11. Harvitt DM, Bonanno JA. Re-evaluation of the oxygen diffusion model for predicting minimum contact lens Dk/t values needed to avoid corneal anoxia. Optom Vis Sci. 1999;76:712-719.
12. Brennan NA. Corneal oxygenation during contact lens wear: comparison of diffusion and EOP-based flux models. Clin Exp Optom. 2005;88:103-108.
13. Larrea X, de Courten C, Feingold V. Bürger J, Büchler P. Oxygen and glucose distribution after intracorneal lens implantation. Optom Vis Sci. 2007;84:1074-1081.
14. Soukane DM, Shirazi-Adl A, Urban JPG. Analysis of nonlinear coupled diffusion of oxygen and lactic acid in intervertebral discs. J Biomech Eng. 2005;127:1121-1126.
15. Lin SH. Oxygen diffusion in a spherical cell with nonlinear oxygen uptake kinetics. J Theor Biol. 1976;60:449-457.
16. Brennan NA. A model of oxygen flux trough contact lenses. Cornea. 2001;20:104-108.
17. Bibby SRS, Jones DA, Ripley RM, Urban JPG. Metabolism of the intervertebral disc: effects of low level of oxygen, glucose and pH on rates of energy metabolism of bovine nucleus pulposus cells. Spine. 2005;30:487-496.
18. Harvitt DM, Bonanno JA. pH dependence of corneal oxygen consumption. Invest Ophthalmol Vis Sci. 1998;39:2778-2781.
19. Holden BA, Mertz GW. Critical oxygen levels to avoid corneal edema for daily and extended wear contact lenses. Invest Ophthalmol Vis Sci. 1984;25:1161-1167.
20. Carney LG, Brennan NA. Time course of corneal oxygen uptake during contact lens wear. CLAO J. 1988;14:151-154.