On-chip type cation-exchange chromatography with ferrocene-labeled anti-hemoglobin antibody and electrochemical detector for determination of hemoglobin A1c level

Analytica Chimica Acta

Volumn 638, Issue 2, 2009, Pages 186-190

  Tanaka, Tsuyoshi ^a   Izawa, Kojiro ^a   Okochi, Mina ^a   Lim, Tae Kyu ^b   Watanabe, Shugo ^b   Harada, Manabu ^b   Matsunaga, Tadashi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b Malcom Co Ltd   (Japan)

Author keywords

Electrochemical detection; Ferrocene conjugated antibody; Hemoglobin A1c; On chip type cation exchange chromatography system

Indexed keywords

AG/AGCL; CATION EXCHANGES; CATION-EXCHANGE RESINS; ELECTROCHEMICAL DETECTION; ELECTROCHEMICAL DETECTORS; ELECTROCHEMICAL PROBES; ELECTRODE FLOWS; FERROCENE-CONJUGATED ANTIBODY; GOOD CORRELATIONS; HEMOGLOBIN A1C; LINEAR RELATIONSHIPS; MARKER PROTEINS; ON-CHIP TYPE CATION-EXCHANGE CHROMATOGRAPHY SYSTEM; SEPARATION CONDITIONS; SYRINGE PUMPS; TYPE SYSTEMS;

ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROCHEMICAL CELLS; ELECTROCHEMICAL OXIDATION; HEMOGLOBIN; IRON COMPOUNDS; MONOCLONAL ANTIBODIES; RESINS; SILICONES;

POSITIVE IONS;

FERROCENE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN; HEMOGLOBIN A0; HEMOGLOBIN A1B; HEMOGLOBIN A1C; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY FCAB; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; ARTICLE; BLOOD SAMPLING; ELECTROCHEMISTRY; HEMOGLOBIN DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ION EXCHANGE CHROMATOGRAPHY; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; CALIBRATION; CHROMATOGRAPHY, ION EXCHANGE; ELECTROCHEMISTRY; FERROUS COMPOUNDS; HEMOGLOBIN A, GLYCOSYLATED; MICROCHIP ANALYTICAL PROCEDURES; OXIDATION-REDUCTION; POINT-OF-CARE SYSTEMS; STAINING AND LABELING; TIME FACTORS;

EID: 62649152390     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2009.02.016     Document Type: Article

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