Adrenal endothelin-1 levels are not associated with aldosterone secretion in primary aldosteronism

European Journal of Endocrinology

Volumn 160, Issue 3, 2009, Pages 453-458

  Morello, Fulvio ^a   Schiavone, D ^a   Mengozzi, G ^b   Bertello, C ^a   Liew, C C ^c   Bisbocci, D ^a   Mulatero, P ^a   Veglio, F ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MOLINETTE HOSPITAL   (Italy)

^c GeneNews Ltd   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ENDOTHELIN 1; HYDROCORTISONE; MESSENGER RNA; ASPARTIC PROTEINASE; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN-CONVERTING ENZYME 1; METALLOPROTEINASE;

ADRENAL CORTEX ADENOMA; ADRENAL GLAND; ADRENAL HYPERPLASIA; ADULT; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; INFERIOR CAVA VEIN; MALE; MICROARRAY ANALYSIS; PLASMA RENIN ACTIVITY; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; RADIOIMMUNOASSAY; UPREGULATION; ADENOMA; ADRENAL TUMOR; AGED; BLOOD; GENETICS; HYPERALDOSTERONISM; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; SECRETION;

ADENOMA; ADRENAL GLAND NEOPLASMS; ADRENAL GLANDS; AGED; ALDOSTERONE; ASPARTIC ENDOPEPTIDASES; ENDOTHELIN-1; FEMALE; HUMANS; HYPERALDOSTERONISM; MALE; METALLOENDOPEPTIDASES; MIDDLE AGED; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RNA, MESSENGER;

EID: 62649123348     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-08-0828     Document Type: Article

References (29)

1. Giaid A, Yanagisawa M, Langleben D, Michel RP, Levy R, Shennib H, Kimura S, Masaki T, Duguid WP & Stewart DJ. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. New England Journal of Medicine 1993 328 1732-1739.
2. Rubin LJ, Badesch DB, Barst RJ, Galie N, Black CM, Keogh A, Pulido T, Frost A, Roux S, Leconte I, Landzberg M, Simonneau G & the Bosentan Randomized Trial of Endothelin Antagonist Therapy Study G. Bosentan therapy for pulmonary arterial hypertension. New England Journal of Medicine 2002 346 896-903.
3. Krum H, Viskoper RJ, Lacourciere Y, Budde M, Charlon V & The Bosentan Hypertension I. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. New England Journal of Medicine 1998 338 784-791.
4. Kiowski W, Sutsch G, Hunziker P, Muller P, Kim J, Oechslin E, Schmitt R, Jones R & Bertel O. Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet 1995 346 732-736.
5. Cozza EN, Gomez-Sanchez CE, Foecking MF & Chiou S. Endothelin binding to cultured calf adrenal zona glomerulosa cells and stimulation of aldosterone secretion. Journal of Clinical Investigation 1989 84 1032-1035.
6. Morishita R, Higaki J & Ogihara T. Endothelin stimulates aldosterone biosynthesis by dispersed rabbit adreno-capsular cells. Biochemical and Biophysical Research Communications 1989 160 628-632.
7. Cozza EN, Chiou S & Gomez-Sanchez CE. Endothelin-1 potentiation of angiotensin II stimulation of aldosterone production. American Journal of Physiology 1992 262 R85-R89.
8. Hinson JP, Kapas S, Teja R & Vinson GP. Effect of the endothelins on aldosterone secretion by rat zona glomerulosa cells in vitro. Journal of Steroid Biochemistry and Molecular Biology 1991 40 437-439.
9. Delarue C, Delton I, Fiorini F, Homo-Delarche F, Fasolo A, Braquet P & Vaudry H. Endothelin stimulates steroid secretion by frog adrenal gland in vitro: evidence for the involvement of prostaglandins and extracellular calcium in the mechanism of actin of endothelin. Endocrinology 1990 127 2001-2008.
10. Rosolowsky LJ & Campbell WB. Endothelin enhances adrenocorticotropin-stimulated aldosterone release from cultured bovine adrenal cells. Endocrinology 1990 126 1860-1866.
11. Zeng ZP, Naruse M, Guan BJ, Naruse K, Sun ML, Zang MF, Demura H & Shi YF. Endothelin stimulates aldosterone secretion in vitro from normal adrenocortical tissue, but not adenoma tissue, in primary aldosteronism. Journal of Clinical Endocrinology and Metabolism 1992 74 874-878.
12. Delarue C, Conlon JM, Remy-Jouet I, Fournier A & Vaudry H. Endothelins as local activators of adrenocortical cells. Journal of Molecular Endocrinology 2004 32 1-7.
13. Wong S, Brennan FE, Young MJ, Fuller PJ & Cole TJ. A direct effect of aldosterone on endothelin-1 gene expression in vivo. Endocrinology 2007 148 1511-1517.
14. Wolf SC, Schultze M, Risler T, Rieg T, Lang F, Schulze-Osthoff K & Brehm BR. Stimulation of serum- and glucocorticoid-regulated kinase-1 gene expression by endothelin-1. Biochemical Pharmacology 2006 71 1175.
15. Gumz ML, Popp MP, Wingo CS & Cain BD. Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line. American Journal of Physiology. Renal Physiology 2003 285 F664-F673.
16. Rossi G, Albertin G, Belloni A, Zanin L, Biasolo MA, Prayer-Galetti T, Bader M, Nussdorfer GG, Palu G & Pessina AC. Gene expression, localization, and characterization of endothelin A and B receptors in the human adrenal cortex. Journal of Clinical Investigation 1994 94 1226-1234.
17. Egidy G, Baviera E, Ciuffo G, Corvol P & Pinet F. Localization of the endothelin system in aldosterone-producing adenomas. Hypertension 2001 38 1137-1142.
18. Rossi G, Belloni AS, Albertin G, Zanin L, Biasolo MA, Nussdorfer GG, Palu G & Pessina AC. Endothelin-1 and its receptors A and B in human aldosterone-producing adenomas. Hypertension 1995 25 842-847.
19. Mulatero P, Dluhy RG, Giacchetti G, Boscaro M, Veglio F & Stewart PM. Diagnosis of primary aldosteronism: from screening to subtype differentiation. Trends in Endocrinology and Metabolism 2005 16 114-119.
20. Mulatero P, Stowasser M, Loh K-C, Fardella CE, Gordon RD, Mosso L, Gomez-Sanchez CE, Veglio F & Young WF Jr. Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. Journal of Clinical Endocrinology and Metabolism 2004 89 1045-1050.
21. Veglio F, Melchio R, Rabbia F & Chiandussi L. Plasma immunoreactive endothelin-1 in primary hyperaldosteronism. American Journal of Hypertension 1994 7 559-561.
22. Letizia C, De Toma G, Cerci S, Scuro L, De Ciocchis A, D'Ambrosio C, Massa R, Cavallaro A & Scavo D. Plasma endothelin-1 levels in patients with aldosterone-producing adenoma and pheochromocytoma. Clinical and Experimental Hypertension 1996 18 921-931.
23. Mulatero P, Bertello C, Rossato D, Mengozzi G, Milan A, Garrone C, Giraudo G, Passarino G, Garabello D, Verhovez A, Rabbia F & Veglio F. Roles of clinical criteria, CT scan and adrenal vein sampling in differential diagnosis of primary aldosteronism subtypes. Journal of Clinical Endocrinology and Metabolism 2008 93 1366-1371.
24. Mulatero P, Milan A, Fallo F, Regolisti G, Pizzolo F, Fardella C, Mosso L, Marafetti L, Veglio F & Maccario M. Comparison of confirmatory tests for the diagnosis of primary aldosteronism. Journal of Clinical Endocrinology and Metabolism 2006 91 2618-2623.
25. Mulatero P, Curnow KM, Aupetit-Faisant B, Foekling M, Gomez-Sanchez C, Veglio F, Jeunemaitre X, Corvol P & Pascoe L. Recombinant CYP11B genes encode enzymes that can catalyze conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol, and 18-oxocortisol. Journal of Clinical Endocrinology and Metabolism 1998 83 3996-4001.
26. Morello F, de Boer RA, Steffensen KR, Gnecchi M, Chisholm JW, Boomsma F, Anderson LM, Lawn RM, Gustafsson JK, Lopez-Ilasaca M, Pratt RE & Dzau VJ. Liver X receptors alpha and beta regulate renin expression in vivo. Journal of Clinical Investigation 2005 115 1913-1922.
27. Han M, Liew CT, Zhang HW, Chao S, Zheng R, Yip KT, Song Z-Y, Li HM, Geng XP, Zhu LX, Lin J-J, Marshall KW & Liew CC. Novel blood-based, five-gene biomarker set for the detection of colorectal cancer. Clinical Cancer Research 2008 14 455-460.
28. Lenzini L, Seccia TM, Aldighieri E, Belloni AS, Bernante P, Giuliani L, Nussdorfer GG, Pessina AC & Rossi GP. Heterogeneity of aldosterone-producing adenomas revealed by a whole transcriptome analysis. Hypertension 2007 50 1106-1113.
29. Saner-Amigh K, Mayhew BA, Mantero F, Schiavi F, White PC, Rao CV & Rainey WE. Elevated expression of luteinizing hormone receptor in aldosterone-producing adenomas. Journal of Clinical Endocrinology and Metabolism 2006 91 1136-1142.