Low O2 metabolism of HepG2 cells cultured at high density in a 3D microstructured scaffold

Biomedical Microdevices

Volumn 11, Issue 2, 2009, Pages 485-494

  Provin, Christophe ^a   Takano, Kiyoshi ^a   Yoshida, Tomomi ^a   Sakai, Yasuyuki ^a   Fujii, Teruo ^a   Shirakashi, Ryo ^a  

^a INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

Author keywords

Hepatocyte; Michaelis Menten; Microfluidic; Model; PDMS; Perfusion

Indexed keywords

HEPATOCYTE; MICHAELIS-MENTEN; MICROFLUIDIC; PDMS; PERFUSION;

BIOCHEMISTRY; CELL CULTURE; INTEGRATED CIRCUITS; METABOLISM; MICROCHANNELS; NONMETALS; SCAFFOLDS; SILICONES; SURFACE DIFFUSION; THREE DIMENSIONAL;

OXYGEN SUPPLY;

MOLECULAR SCAFFOLD; OXYGEN;

ARTICLE; CELL ADHESION; CELL COUNT; CELL DENSITY; CELL METABOLISM; CELL STRAIN HEPG2; CONTROLLED STUDY; CULTURE MEDIUM; FLOW RATE; GEOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; LIVER CELL; OXYGEN CONSUMPTION; OXYGEN SUPPLY; PERFUSION; PRIORITY JOURNAL; SHEAR STRESS; SIMULATION; CELL LINE; COMPUTER AIDED DESIGN; CULTURE TECHNIQUE; CYTOLOGY; EQUIPMENT; EQUIPMENT DESIGN; INSTRUMENTATION; METABOLISM; METHODOLOGY; MICROFLUIDIC ANALYSIS; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

CELL ADHESION; CELL CULTURE TECHNIQUES; CELL LINE; COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HEPATOCYTES; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; OXYGEN; PERFUSION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 62649094415     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10544-008-9254-8     Document Type: Article

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