Mapping the zonal organization of tumor perfusion and permeability in a rat glioma model by using dynamic contrast-enhanced synchrotron radiation CT

Radiology

Volumn 250, Issue 3, 2009, Pages 692-702

  Balvay, Daniel ^a,f   Troprès, Irène ^b,d   Billet, Romain ^b   Joubert, Aurélie ^c   Péoc'H, Michel ^e   Cuenod, Charlesa ^a,f   Le Due, Géraldine ^b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^c INSERM   (France)

^d UNIV GRENOBLE ALPES   (France)

^e SERVICE DE NEUROLOGIE   (France)

^f HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IOBITRIDOL; IODINE; IOMEPROL;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VOLUME; BRAIN MAPPING; CANCER SIZE; CAUDATE NUCLEUS; COMPARTMENT MODEL; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG PENETRATION; DRUG TISSUE LEVEL; FEASIBILITY STUDY; GLIOMA; IMAGE QUALITY; INFORMATION PROCESSING; MALE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SYNCHROTRON RADIATION; TISSUE BLOOD FLOW; TISSUE PERFUSION; TUMOR VASCULARIZATION; WISTAR RAT;

ANIMALS; BRAIN NEOPLASMS; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; GLIOMA; IOPAMIDOL; MALE; NEOVASCULARIZATION, PATHOLOGIC; RADIOGRAPHIC IMAGE ENHANCEMENT; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY; SYNCHROTRONS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 62649093112     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2501071929     Document Type: Article

References (63)

1. Deorah S, Lynch CF, Sibenaller ZA, Ryken TC. Trends in brain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to 2001. Neurosurg Focus 2006;20:E1.
2. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000;6:389-395.
3. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-257.
4. Folkman J. Clinical applications of research on angiogenesis. N Engl J Med 1995;333:1757- 1763.
5. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1:27-31.
6. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992;267:10931-10934.
7. Leon SP, Folkerth RD, Black PM. Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer 1996;77: 362-372.
8. 8.ToFts PS, Benton CE, Weil RS, et al. Quantitative analysis of whole-tumor Gd enhancement histograms predicts malignant transformation in low-grade gliomas. J Magn Reson Imaging 2007;25:208-214.
9. Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Curr Neurol Neurosci Rep 2005;5:186-197.
10. Roberts HC, Roberts TP, Lee TY, Dillon WP. Dynamic, contrast-enhanced CT of human brain tumors: quantitative assessment of blood volume, blood flow, and microvascular permeability-report of two cases. AJNR Am J Neuroradiol 2002;23:828- 32.
11. Purdie TG, Henderson E, Lee TY. Functional CT imaging of angiogenesis in rabbit VX2 soft tissue tumour. Phys Med Biol 2001;46:3161- 3175.
12. Leggett DA, Miles KA, Kelley BB. Blood-brain barrier and blood volume imaging of cerebral glioma using functional CT: a pictorial review. Eur J Radiol 1999;30:185-190.
13. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY. A CT method to measure hemodynamics in brain tumors: validation and application of cerebral blood flow maps. AJNR Am J Neuroradiol 2000;21:462- 470.
14. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY. Dynamic CT measurement of cerebral blood flow: a validation study. AJNR Am J Neuroradiol 1999;20:63-73.
15. Roberts HC, Roberts TP, Brasch RC, Dillon WP. Quantitative measurement of microvascular permeability in human brain tumors achieved using dynamic contrast-enhanced MR imaging: correlation with histologic grade. AJNR Am J Neuroradiol 2000;21:891- 899.
16. Barbier EL, Lamalle L, Decorps M. Methodology of brain perfusion imaging. J Magn Reson Imaging 2001;13:496 -520.
17. Henderson E, Sykes J, Drost D, Weinmann HJ, Rutt BK, Lee TY. Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents. J Magn Reson Imaging 2000;12:991-1003.
18. Tofts PS, Brix G, Buckley DL, et al. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999;10:223-232.
19. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. I. Fundamental concepts. Magn Reson Med 1991;17:357- 367.
20. Dilmanian FA, Garrett RF, Thomlinson WC, et al. Multiple energy computed tomography for neuroradiology with monochromatic x-rays from the national synchrotron light source. Phys Med 1991;6:301-307.
21. Dilmanian FA, Garrett RF, Thomlinson WC, et al. Computed tomography with monochromatic x-rays from the national synchrotron light source. Nucl Instrum Methods Phys Res Sect B 1991;56:1208-1213.
22. Elleaume H, Charvet AM, Corde S, Esteve F, Le Bas JF. Performance of computed tomography for contrast agent concentration measurements with monochromatic x-ray beams: comparison of k-edge versus temporal subtraction. Phys Med Biol 2002;47:3369 -3385.
23. Le Duc G, Corde S, Charvet AM, et al. In vivo measurement of gadolinium concentration in a rat glioma model by monochromatic quantitative computed tomography: comparison between gadopentetate dimeglumine and gadobutrol. Invest Radiol 2004;39:385-393.
24. Adam JF, Biston MC, Joubert A, et al. Enhanced delivery of iodine for synchrotron stereotactic radiotherapy by means of intracarotid injection and blood-brain barrier disruption: quantitative iodine biodistribution studies and associated dosimetry. Int J Radiat Oncol Biol Phys 2005;61:1173-1182.
25. Adam JF, Elleaume H, Le Duc G, et al. Absolute cerebral blood volume and blood flow measurements based on synchrotron radiation quantitative computed tomography. J Cereb Blood Flow Metab 2003;23:499 -512.
26. Tropres I, Grimault S, Vaeth A, et al. Vesselsize imaging. Magn Reson Med 2001;45:397- 408.
27. Le Duc G, Peoc'h M, Remy C, et al. Use of T(2)-weighted susceptibility contrast MRI for mapping the blood volume in the glioma-bearing rat brain. Magn Reson Med 1999;42:754- 761.
28. Peoc'h M, Le Duc G, Trayaud A, et al. Quantification and distribution of neovascularization following microinjection of C6 glioma cells in rat brain. Anticancer Res 1999;19:3025-3030.
29. Grobben B, De Deyn PP, Slegers H. Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion. Cell Tissue Res 2002;310:257-270.
30. Balvay D, Frouin F, Calmon G, et al. New criteria for assessing fit quality in dynamic contrast- enhanced T1-weighted MRI for perfusion and permeability imaging. Magn Reson Med 2005; 54:868-877.
31. Benda P, Someda K, Messer J, Sweet WH. Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture. J Neurosurg 1971;34:310-323.
32. Benabid AL, Remy C, Chauvin C. Experimental models of rat brain tumors by stereotactic injection of C6 glioma and HTC hepatoma cell lines. In: Walker MD, Thomas DGT, eds. Biology of brain tumour. Boston, Mass: Martinus Nijhoff, 1986; 221-226.
33. Kobayashi N, Allen N, Clendenon NR, Ko LW. An improved rat brain-tumor model. J Neurosurg 1980;53:808-815.
34. Paxinos G, Watson C, eds. The rat brain in stereotaxic coordinates. New York, NY: Academic, 1986.
35. Elleaume H, Charvet AM, Berkvens P, et al. Instrumentation of the ESRF medical imaging facility. Nucl Instrum Methods Phys Res Sect A 1999;428:513-527.
36. Suortti P, Fiedler S, Bravin A, et al. Fixed-exit monochromator for computed tomography with synchrotron radiation at energies 18-90 keV. J Synchrotron Radiat 2000;7:340-347.
37. Dilmanian FA, Wu XY, Parsons EC, et al. Single- and dual-energy CT with monochromatic synchrotron x-rays. Phys Med Biol 1997;42: 371-387.
38. Herman G, Lewitt R, Ohdner D, Rowland S. SNARK89: a programming system for image reconstruction from projections. Philadelphia, Pa: University of Pennsylvania Press, 1989.
39. Rosati G. Clinical pharmacology of iomeprol. Eur J Radiol 1994;18(suppl 1):S51-S60.
40. Idee JM, Bault C, Beaufils H, et al. Pharmacologic profile of iobitridol, a nonionic iodinated contrast medium. Acta Radiol Suppl 1996;400:35- 48.
41. Scremin OU. Cerebral vascular system. In: Paxinos G, ed. The rat nervous system. 2nd ed. New York, NY: Academic, 1995; 3-35.
42. Scremin OU, Sonnenschein RR, Rubinstein EH. Cerebrovascular anatomy and blood flow measurements in the rabbit. J Cereb Blood Flow Metab 1982;2:55-66.
43. Bereczki D, Wei L, Acuff V, et al. Technique- dependent variations in cerebral microvessel blood volumes and hematocrits in the rat. J Appl Physiol 1992;73:918-924.
44. Cremer JE, Seville MP. Regional brain blood flow, blood volume, and haematocrit values in the adult rat. J Cereb Blood Flow Metab 1983; 3:254-256.
45. Nakagawa H, Lin SZ, Bereczki D, et al. Blood volumes, hematocrits, and transit-times in pa- renchymal microvascular systems in the rat brain. In: Le Bihan D, ed. Diffusion and perfu- sion magnetic resonance. New York, NY: Raven, 1995; 193-200.
46. Payen JF, Vath A, Koenigsberg B, Bourlier V, Decorps M. Regional cerebral plasma volume response to carbon dioxide using magnetic resonance imaging. Anesthesiology 1998;88:984-992.
47. Brix G, Bahner ML, Hoffmann U, Horvath A, Schreiber W. Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CT-initial experience. Radiology 1999;210:269-276.
48. Pradel C, Siauve N, Bruneteau G, et al. Reduced capillary perfusion and permeability in human tumour xenografts treated with the VEGF signalling inhibitor ZD4190: an in vivo assessment using dynamic MR imaging and macromolecular contrast media. Magn Reson Imaging 2003;21:845-851.
49. Kety SS. The theory and applications of the exchange of inert gas at the lungs and tissues. Pharmacol Rev 1951;3:1- 41.
50. Larsson HB, Stubgaard M, Frederiksen JL, Jensen M, Henriksen O, Paulson OB. Quantita- tion of blood-brain barrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors. Magn Reson Med 1990;16:117-131.
51. Patlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983;3:1-7.
52. Henderson E, Rutt BK, Lee TY. Temporal sampling requirements for the tracer kinetics modeling of breast disease. Magn Reson Imaging 1998;16:1057-1073.
53. Burger PC. Pathologic anatomyand CT correlations in the glioblastoma multiforme. Appl Neurophysiol 1983;46:180-187.
54. Johnson TR, Nikolaou K, Becker A, et al. Dual- source CT for chest pain assessment. Eur Radiol 2008;18:773-780.
55. Kinahan PE, Alessio AM, Fessler JA. Dual energy CT attenuation correction methods for quantitative assessment of response to cancer therapy with PET/CT imaging. Technol Cancer Res Treat 2006;5:319-327.
56. Ruzsics B, Lee H, Powers ER, Flohr TG, Costello P, Schoepf UJ. Images in cardiovascular medicine: myocardial ischemia diagnosed by dual-energy computed tomography- correlation with single-photon emission computed tomography. Circulation 2008;117:1244-1245.
57. Segers J, Le Duc G, Laumonier C, Tropres I, Elst LV, Muller RN. Evaluation of Gd-EOBDTPA uptake in a perfused and isolated mouse liver model: correlation between magnetic resonance imaging and monochromatic quantitative computed tomography. Invest Radiol 2005;40:574-582.
58. Alric C, Taleb J, Le Duc G, et al. Gadolinium chelate coated gold nanoparticles as contrast agents for both x-ray computed tomography and magnetic resonance imaging. J Am Chem Soc 2008;130:5908-5915.
59. de Bazelaire C, Siauve N, Fournier L, et al. Comprehensive model for simultaneous MRI determination ofperfusion and permeabilityus- ing a blood-pool agent in rats rhabdomyosar- coma. Eur Radiol 2005;15:2497-2505.
60. Gaudy JH, Sicard JF, Maneglia R, Quignon M. The effect ofhalothane on blood gases and arterial acid-base equilibrium in intact rats and in chemo-denervated rats [in French]. Can J Anaesth 1993;40:883-890.
61. Carroll FE, Mendenhall MH, Traeger RH, Brau C, Waters JW. Pulsed tunable monochromatic x-ray beams from a compact source: new opportunities. AJR Am J Roentgenol 2003;181:1197-1202.
62. Tropres I, Le Duc G, Bouhlal Y, et al. Cerebral blood volume measurements in the brain: comparison between synchrotron radiation computed tomography and MRI [abstr]. In: Proceedings of the 10th Meeting of the International Society for Magnetic Resonance in Medicine. Berkeley, Calif: International Society for Magnetic Resonance in Medicine, 2002.
63. Adam JF, Nemoz C, Bravin A, et al. High resolution blood-brain barrier permeability and blood volume imaging using quantitative synchrotron radiation computed tomography: study on an F98 rat brain glioma. J Cereb Blood Flow Metab 2005;25:145-153.