Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: Docking-based CoMFA and CoMSIA analyses

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 2059-2070

  Cichero, Elena ^a   Cesarini, Sara ^a   Fossa, Paola ^a   Spallarossa, Andrea ^a   Mosti, Luisa ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

3D QSAR; CoMFA; CoMSIA; HIV 1; Reverse transcriptase; Thiocarbamates

Indexed keywords

RNA DIRECTED DNA POLYMERASE INHIBITOR; THIOCARBAMIC ACID DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG POTENCY; MOLECULAR DOCKING; MUTANT; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

COMPUTER SIMULATION; HIV REVERSE TRANSCRIPTASE; MODELS, MOLECULAR; PROTEIN BINDING; REVERSE TRANSCRIPTASE INHIBITORS; THIOCARBAMATES;

EID: 62549150308     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.10.014     Document Type: Article

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