Effects of zinc phthalocyanine tetrasulfonate-based photodynamic therapy on rat brain isolated mitochondria

Chemico-Biological Interactions

Volumn 179, Issue 2-3, 2009, Pages 402-406

  Medina, Wanessa Silva Garcia ^a   Santos, Neife Aparecida Guinaim dos ^a   Curti, Carlos ^a   Tedesco, Antonio Cláudio ^a   Santos, Antonio Cardozo dos ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anticancer therapy; Apoptosis; Brain tumors; Mitochondrial toxicity; Photodynamic therapy (PDT); Zinc phthalocyanine tetrasulfonate (ZnPcS4)

Indexed keywords

CALCIUM ION; CYCLOSPORIN A; CYTOCHROME C; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG; ZINC PHTHALOCYANINE TETRASULFONATE;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTROCHEMICAL ANALYSIS; ENZYME RELEASE; INHIBITION KINETICS; LASER; MALE; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTODYNAMICS; RAT;

ANIMALS; BRAIN; CALCIUM; CYTOCHROMES C; INDOLES; LASERS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; RATS; TIME FACTORS;

RATTUS;

EID: 62549143472     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.01.007     Document Type: Article

References (27)

1. Van den Brink-de Vries N.A., Beijnen J.H., Boogerd W., and VanTellingen O. Blood-brain barrier and chemotherapeutic treatment of brain tumors. Expert Rev. Neurother. 6 (2006) 1199-1209
2. Butler J.M., Rapp S.R., and Shaw E.G. Managing the cognitive effects of brain tumor radiation therapy. Curr. Treat. Options Oncol. 7 (2006) 517-523
3. Clarke J.W., Chang E.L., Levin V.A., Mayr N.A., Hong E., Cavaliere R., and Lo S.S. Optimizing radiotherapy schedules for elderly glioblastoma multiforme patients. Expert Rev. Anticancer Ther. 8 (2008) 733-741
4. Pons P., Pittau R.F., Boetto N.A., Garzon R., and Aoki A. Prototype of light source for photodynamic therapy in Centre of Electron Microscopy. Rev. Fac. Cien. Med. Univ. Nac. Cordoba 57 (2000) 31-36
5. Alexandratou E., Yova D., and Loukas S. A confocal microscopy study of the very early cellular response to oxidative stress induced by zinc phthalocyanine sensitization. Free Radic. Biol. Med. 39 (2005) 1119-1127
6. Zhang X., Jiang F., Kalkanis S.N., Yang H., Zhang Z., Katakowski M., Hong X., Zheng X., and Chopp M. Combination of surgical resection and photodynamic therapy of 9L gliosarcoma in the nude rat. Photochem. Photobiol. 82 (2006) 1704-1711
7. Oleinick N.L., and Evans H.H. The photobiology of photodynamic therapy: cellular targets and mechanisms. Radiat. Res. 150 Suppl. 5 (1998) 146-156
8. Lam M., Oleinick N.L., and Nieminen A.L. Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. J. Biol. Chem. 276 (2001) 47379-47386
9. Morgan J., and Oseroff A.R. Mitochondria-based photodynamic anti-cancer therapy. Adv. Drug Deliv. Rev. 49 (2001) 71-86
10. Madsen S.J., Angell-Petersen E., Spetalen S., Carper S.W., Ziegler S.A., and Hirschberg H. Photodynamic therapy of newly implanted glioma cells in the rat brain. Lasers Surg. Med. 38 (2006) 540-548
11. Sibata C.H., Colussi V.C., Oleinick N.L., and Kinsella T.J. Photodynamic therapy: a new concept in medical treatment. Braz. J. Med. Biol. Res. 33 (2000) 869-880
12. 2-based-photodynamic therapy in beagle dogs. Regul. Toxicol. Pharmacol. 47 (2007) 221-231
13. Huang Y., Xu G., Peng Y., Lin H., Zheng X., and Xie M. Zinc phthalocyanine tetrasulfonate (ZnPcS4): a new photosensitizer for photodynamic therapy in choroidal neovascularization. J. Ocul. Pharmacol. Ther. 23 (2007) 377-386
14. Schmidt M.H., Meyer G.A., Reichert K.W., Cheng J., Krouwer H.G., Ozker K., and Whelan H.T. Evaluation of photodynamic therapy near functional brain tissue in patients with recurrent brain tumors. J. Neurooncol. 67 (2004) 201-207
15. Kolárová H., Mosinger J., Lenobel R., Kejlová K., Jírová D., and Strnad M. In vitro toxicity testing of supramolecular sensitizers for photodynamic therapy. Toxicol. In Vitro 17 (2003) 775-778
16. Rosenthal R.E., Hamud F., Fiskum G., Varghese P.J., and Sharpe S. Cerebral ischemia and reperfusion: prevention of brain mitochondrial injury by lidoflazine. J. Cereb. Blood Flow Metab. 7 (1987) 752-758
17. Cain K., and Skilleter D.N. Preparation and use of mitochondria in toxicological research. In: Snell K., and Mullock B. (Eds). Biochemical Toxicology: A Pratical Approach (1987), IRL Press, Oxford 217-254
18. Santos A.C., Uyemura S.A., Santos N.A., Mingatto F.E., and Curti C. Hg(II)-induced renal cytotoxicity: in vitro and in vivo implications for the bioenergetic and oxidative status of mitochondria. Mol. Cell. Biochem. 177 (1997) 53-59
19. Chance B., and Willians G.R. The respiratory chain and oxidative phosphorylation. Adv. Enzymol. 17 (1956) 65-134
20. Emaus R.K., Grunwald R., and Lemasters J.J. Rhodamine-123 as a probe of transmembrane potential in isolated rat-liver mitochondria-spectral and metabolic properties. Biochim. Biophys. Acta 850 (1986) 436-448
21. Scarpa A. Measurements of cation transport with metallochromic indicators. In: Fleisher S., and Packer L. (Eds). Methods in Enzimology (1979), Academic Press, New York 301-352
22. Peng T.I., Chang C.J., Guo M.J., Wang Y.H., Yu J.S., Wu H.Y., and Jou M.J. Mitochondrion-targeted photosensitizer enhances the photodynamic effect-induced mitochondrial dysfunction and apoptosis. Ann. NY Acad. Sci. 1042 (2005) 419-428
23. Halkiotis K., Yova D., and Pantelias G. In vitro evaluation of the genotoxic and clastogenic potential of photodynamic therapy. Mutagenesis 14 (1999) 193-198
24. Kroemer G., Galluzzi L., and Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87 (2007) 99-163
25. Ow Y.L., Green D.R., Hao Z., and Mak T.W. Cytochrome c: functions beyond respiration. Nat. Rev. Mol. Cell. Biol. 9 (2008) 532-542
26. Borgatti-Jeffreys A., Hooser S.B., Miller M.A., and Lucroy M.D. Phase I clinical trial of the use of zinc phthalocyanine tetrasulfonate as a photosensitizer for photodynamic therapy in dogs. Am. J. Vet. Res. 68 (2007) 399-404
27. Josefsen L.B., and Boyle R.W. Photodynamic therapy and the development of metal-based photosensitisers. Metal-based Drugs 2008 (2008) 276109