Multisite trial on efficacy of constraint-induced movement therapy in children with hemiplegia. Study design and methodology

American Journal of Physical Medicine and Rehabilitation

Volumn 88, Issue 3, 2009, Pages 216-230

  Facchin, Paola ^a   Rosa Rizzotto, Melissa ^a   Turconi, Anna Carla ^b   Pagliano, Emanuela ^c   Fazzi, Elisa ^d   Stortini, Massimo ^e   Fedrizzi, Ermellina ^c   Ancona, Vera ^f   Andreucci, Elena ^c   Bon, Francesco ^g   Di Brina, Carlo ^h   Cazzagon, Monica ⁱ   Cerioli, Mario ^j   Germiniasi, Chiara ^b   Inverno, Michelina ^k   La Gamba, Annalisa ^l   Madella Noja, Antonia ^m   Mandalari, Pasquale ⁿ   Martinuzzi, Andrea ^f   Marzaroli, Michela ^o   Megliani, Chiara ^b   Nacinovich, Renata ^p   Picciolini, Odoardo ^q   Sabbadini, Maurizio ^e   Setaro, Angela ^r   Signorini, Sabrina ^d   Tornetta, Lorella ^s   Trabacca, Antonio ^b   Dalla Pozza, Laura Visonà ^a   Zambonin, Fabio ^t   Zumaglini, Ursula ^u   more..

^a UNIVERSITY OF PADOVA   (Italy)

^b Scientific Research Institute Eugenio Medea   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

^e BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^f Scientific Research Institute Eugenio Medea Conegliano VTo   (Italy)

^g Child and Adolescent Psychiaty Unit   (Italy)

^h Viterbo Rehabilitation Center   (Italy)

ⁱ Rehabilitation Center   (Italy)

^j CREMONA HOSPITAL   (Italy)

^k A MANZONI HOSPITAL   (Italy)

^l Invictus Rehabilitation Center   (Italy)

^m TdR AIAS Milano   (Italy)

ⁿ Local Health Unit 5   (Italy)

^o Bergamo Hospital   (Italy)

^p UNIVERSITY OF BRESCIA   (Italy)

^q UNIVERSITY OF MILAN   (Italy)

^r Instituto S Stefano   (Italy)

^s Sant'Anna OIRM Hospital   (Italy)

^t Macchi Hospital   (Italy)

^u Local Health Authority 3   (Italy)

more..

Author keywords

Cerebral palsy; Constraint induced movement therapy; Hemiplegia; Outcomes

Indexed keywords

ARTICLE; BEHAVIOR; CEREBRAL PALSY; CHILD; CLINICAL TRIAL; CONSTRAINT INDUCED THERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; FUNCTIONAL ASSESSMENT; GRIP STRENGTH; HAND FUNCTION; HEMIPLEGIA; HUMAN; MALE; MEDICAL ETHICS; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; OUTCOME ASSESSMENT; PATIENT SATISFACTION; PEDIATRICS; QUESTIONNAIRE; REHABILITATION; SAMPLE SIZE; THERAPY EFFECT; TREATMENT OUTCOME;

CEREBRAL PALSY; CHILD; CHILD, PRESCHOOL; FEMALE; HEMIPLEGIA; HUMANS; ITALY; LOGISTIC MODELS; MALE; MOTION THERAPY, CONTINUOUS PASSIVE; PROSPECTIVE STUDIES; RESEARCH; RESTRAINT, PHYSICAL; TREATMENT OUTCOME; UPPER EXTREMITY;

EID: 62549122541     PISSN: 08949115     EISSN: None     Source Type: Journal    
DOI: 10.1097/PHM.0b013e3181951382     Document Type: Article

References (44)

1. Bottos M, Granato T, Allibrio G, et al: Prevalence of cerebral palsy in north-east Italy from 1965 to 1989. Dev Med Child Neurol 1999;41:26-39
2. Paneth N, Hong T, Korzeniewski S: The descriptive epidemiology of cerebral palsy. Clin Perinatol 2006; 33:251-67
3. Pagliano E, Andreucci E, Bono R, et al: Evolution of upper limb function in children with congenital hemiplegia. Neurol Sci 2001;22:371-5
4. Fedrizzi E, Pagliano E, Andreucci E, et al: Hand function in children with hemiplegic cerebral palsy: Prospective follow-up and functional outcome in adolescence. Dev Med Child Neurol 2003;45:85-91
5. Boyd RN, Morris ME, Graham HK: Management of upper limb dysfunction in children with cerebral palsy: A systematic review. Eur J Neurol 2001;8: 150-66
6. Sundholm LK, Eliasson AC, Forssberg H: Obstetric brachial plexus injuries: Assessment protocol and functional outcome at age 5 years. Dev Med Child Neurol 1998;40:4-11
7. Taub E: Movement in nonhuman primates deprived of somatosensory feedback. Exerc Sport Sci Rev 1976;4:335-74
8. Taub E, Uswatte G, Pidikiti R: Constraint-induced movement therapy: A new family of techniques with broad application to physical rehabilitation - A clinical review. J Rehabil Res Dev 1999;36:237-51
9. Wolf SL, Winstein CJ, Miller JP, et al; EXCITE Investigators: Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA 2006;296:2095-104
10. Hoare BJ, Wasiak J, Imms C, et al: Constraint-induced movement therapy in the treatment of the upper limb in children with hemiplegic cerebral palsy. Cochrane Database Syst Rev 2007;2: CD004149
11. Charles JR, Wolf SL, Schneider JA, et al: Efficacy of a child-friendly form of constraint-induced movement therapy in hemiplegic cerebral palsy: A randomized control trial. Dev Med Child Neurol 2006; 48:635-42
12. Eliasson AC, Krumlinde-sundholm L, Shaw K, et al: Effects of constraint-induced movement therapy in young children with hemiplegic cerebral palsy: An adapted model. Dev Med Child Neurol 2005;47: 266-75
13. Charles J, Lavinder G, Gordon AM: Effects of constraint-induced therapy on hand function in children with hemiplegic cerebral palsy. Pediatr Phys Ther 2001;13:68-76
14. Gordon AM, Charles J, Wolf SL: Methods of constraint-induced movement therapy for children with hemiplegic cerebral palsy: Development of a child-friendly intervention for improving upper-extremity function. Arch Phys Med Rehabil 2005;86:837-44
15. Sung IY, Ryu JS, Pyun SB, et al: Efficacy of forced-use therapy in hemiplegic cerebral palsy. Arch Phys Med Rehabil 2005;86:2195-8
16. Taub E, Ramey SL, DeLuca S, et al: Efficacy of constraint-induced movement therapy for children with cerebral palsy with asymmetric motor impairment. Pediatrics 2004;113:305-12
17. Glover JE, Mateer CA, Yoell C, et al: The effectiveness of constraint induced movement therapy in two young children with hemiplegia. Pediatr Rehabil 2002;5:125-31
18. DeLuca SC, Echols R, Ramey SL, et al: Pediatric constraint induced movement therapy for a young child with cerebral palsy: Two episodes care. Phys Ther 2003;83:1003-13
19. Eliasson A-C, Bonnier B, Krumlinde-Sundholm L: Clinical experience of constraint induced movement therapy in small children with hemiplegic cerebral palsy - A day camp model. Dev Med Child Neurol 2003;45:357-60
20. Charles JR, Gordon AM: A repeated course of constraint-induced movement therapy results in further improvement. Dev Med Child Neurol 2007;49:770-3
21. Gordon AM, Charles J, Wolf SL: Methods of constraint induced movement therapy for children with hemiplegic cerebral palsy: Development of a child-friendly intervention for improving upper extremity function. Arch Phys Med Rehabil 2005;86:837-44
22. Taub E, Wolf SL: Constraint induction techniques to facilitate upper extremity use in stroke patients. Top Stroke Rehabil 1997;3:1-24
23. Gordon AM, Schneider JA, Chinnan A, et al: Efficacy of a hand-arm bimanual intensive therapy (HABIT) in children with hemiplegic cerebral palsy: A randomized control trial. Dev Med Child Neurol 2007; 49:830-8
24. Cornfield J: Randomization by group: A formal analysis. Am J Epidemiol 1978;108:100-2
25. Donner A, Klar N: Design and Analysis of Cluster Randomization Trials in Health Research. London, Arnold, 2000
26. Kerry SM, Bland JM: Analysis of a trial randomised in clusters. BMJ 1998;316:54
27. Kerry SM, Bland JM: Sample size in cluster randomisation. BMJ 1998;316:549
28. Klar N, Donner A: Current and future challenges in the design and analysis of cluster randomization trials. Stat Med 2001;20:3729-40
29. Keiser M, Friede T: Re-calculating the sample size in internal pilot study designs with control of the type I error rate. Stat Med 2000;19:901-11
30. Hagberg G, Hagberg G, Glow I: The changing panorama of cerebral palsy in Sweden 1954-1970. II. Analysis of the various syndromes. Acta Paediatr Scand 1975;64:193-200
31. Beckung E, Hagberg G: Neuroimpairments, activity limitations, and participation restrictions in children with cerebral palsy. Dev Med Child Neurol 2002;44:309-16
32. Eliasson AC, Krumlinde-Sundholm L, Rosblad B, et al: The Manual Ability Classification System (MACS) for children with cerebral palsy: Scale development and evidence of validity and reliability. Dev Med Child Neurol 2006;48:549-54
33. Sakzewski L, Ziviani J, Van Eldik N: Test/retest and inter-rater agreement of the Quality of Upper Extremities Skills Test (QUEST) for older children with acquired brain injuries. Phys Occup Ther Pediatr 2001;21:59-67
34. DeMatteo C, Law M, Russell D, et al: The quality of upper extremity skills test. Phys Occup Ther Pediatr 1993;13:833-45
35. Molteni B, Oleari G, Fedrizzi E, et al: Relation between CT patterns, clinical findings and etiological factors in children born at term, affected by congenital hemiparesis. Neuropediatr 1987;18:75-80
36. Fedrizzi E, Oleari G, Inverno M, et al: Motor performance assessment in children with cerebral palsy, in Fedrizzi E, Avanzini G, Crenna P (eds): Motor Development in Childhood. London, John Libbey, 1994, pp 51-8
37. Touwen BCL: Neurological Development in Infancy. Clinics in Developmental Medicine No. 58. London, Spastics International Medical Publishers (Mac Keith Press), 1976
38. Abidin RR: Parenting Stress Index, ed 3. Odessa, FL, Psychological Assessment Resources, 1995
39. Achenbach TM, Edelbrock CS: Behavioral problems and competencies reported by parents of normal and disturbed children aged four through sixteen. Monogr Soc Res Child Dev 1981;46:1-82
40. Martin JH, Choy M, Pullman S, et al: Corticospinal system development depends on motor experience. J Neurosci 2004;24:2122-32
41. Fuhrer MJ: Overview of clinical trials in medical rehabilitation: Impetuses, challenges, and needed future directions. Am J Phys Med Rehabil 2003;82(10 suppl):S8-S15
42. Meinert CI: Clinical Trials: Design, Conduct, and Analysis. New York, Oxford University Press, 1986
43. Fuhrer MJ: Conducting multiple-site clinical trials in medical rehabilitation research. Am J Phys Med Rehabil 2005;84:823-31
44. Fitzgerald GK, Delitto A: Considerations for planning and conducting clinic-based research in physical therapy. Phys Ther 2001;81:1446-54