메뉴 건너뛰기




Volumn 30, Issue 3, 2009, Pages 494-499

Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; B RAF KINASE; K RAS PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN P53;

EID: 62449313740     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp017     Document Type: Article
Times cited : (66)

References (50)
  • 1
    • 0141576687 scopus 로고    scopus 로고
    • The significance of unstable chromosomes in colorectal cancer
    • Rajagopalan,H. et al. (2003) The significance of unstable chromosomes in colorectal cancer. Nat. Rev. Cancer, 3, 695-701.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 695-701
    • Rajagopalan, H.1
  • 2
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer,C. et al. (1997) Genetic instability in colorectal cancers. Nature, 386, 623-627.
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1
  • 3
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein,B. et al. (1988) Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319, 525-532.
    • (1988) N. Engl. J. Med , vol.319 , pp. 525-532
    • Vogelstein, B.1
  • 4
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel,H. et al. (2005) Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N. Engl. J. Med., 352, 1851-1860.
    • (2005) N. Engl. J. Med , vol.352 , pp. 1851-1860
    • Hampel, H.1
  • 5
    • 6944229909 scopus 로고    scopus 로고
    • The clinical features of rectal cancers with high-frequency microsatellite instability (MSI-H) in Japanese males
    • Ishikubo,T. et al. (2004) The clinical features of rectal cancers with high-frequency microsatellite instability (MSI-H) in Japanese males. Cancer Lett., 216, 55-62.
    • (2004) Cancer Lett , vol.216 , pp. 55-62
    • Ishikubo, T.1
  • 6
    • 20244386395 scopus 로고    scopus 로고
    • Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer
    • Pinol,V. et al. (2005) Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer. JAMA, 293, 1986-1994.
    • (2005) JAMA , vol.293 , pp. 1986-1994
    • Pinol, V.1
  • 7
    • 0034997971 scopus 로고    scopus 로고
    • Microsatellite instability and the clinicopathological features of sporadic colorectal cancer
    • Ward,R. et al. (2001) Microsatellite instability and the clinicopathological features of sporadic colorectal cancer. Gut, 48, 821-829.
    • (2001) Gut , vol.48 , pp. 821-829
    • Ward, R.1
  • 8
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz,S. et al. (1995) Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science, 268, 1336-1338.
    • (1995) Science , vol.268 , pp. 1336-1338
    • Markowitz, S.1
  • 9
    • 16144368515 scopus 로고    scopus 로고
    • Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours
    • Souza,R.F. et al. (1996) Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat. Genet., 14, 255-257.
    • (1996) Nat. Genet , vol.14 , pp. 255-257
    • Souza, R.F.1
  • 10
    • 7344243778 scopus 로고    scopus 로고
    • CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer
    • Wicking,C. et al. (1998) CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer. Oncogene, 17, 657-659.
    • (1998) Oncogene , vol.17 , pp. 657-659
    • Wicking, C.1
  • 11
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • Rampino,N. et al. (1997) Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science, 275, 967-969.
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N.1
  • 12
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland,C.R. et al. (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res., 58, 5248-5257.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1
  • 13
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau,S.N. et al. (1993) Microsatellite instability in cancer of the proximal colon. Science, 260, 816-819.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1
  • 14
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov,Y. et al. (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature, 363, 558-561.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1
  • 15
    • 0034642605 scopus 로고    scopus 로고
    • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
    • Gryfe,R. et al. (2000) Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N. Engl. J. Med., 342, 69-77.
    • (2000) N. Engl. J. Med , vol.342 , pp. 69-77
    • Gryfe, R.1
  • 16
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • Kim,H. et al. (1994) Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am. J. Pathol., 145, 148-156.
    • (1994) Am. J. Pathol , vol.145 , pp. 148-156
    • Kim, H.1
  • 17
    • 0030465095 scopus 로고    scopus 로고
    • Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer
    • Risio,M. et al. (1996) Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer. Cancer Res., 56, 5470-5474.
    • (1996) Cancer Res , vol.56 , pp. 5470-5474
    • Risio, M.1
  • 18
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman,J.G. et al. (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl Acad. Sci. USA, 95, 6870-6875.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 6870-6875
    • Herman, J.G.1
  • 19
    • 0032146118 scopus 로고    scopus 로고
    • Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
    • Cunningham,J.M. et al. (1998) Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res. 58, 3455-3460.
    • (1998) Cancer Res , vol.58 , pp. 3455-3460
    • Cunningham, J.M.1
  • 20
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach,F.S. et al. (1993) Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell, 75, 1215-1225.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1
  • 21
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
    • Bronner,C.E. et al. (1994) Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature, 368, 258-261.
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1
  • 22
    • 0028350601 scopus 로고
    • Mutation of a mutL homolog in hereditary colon cancer
    • Papadopoulos,N. et al. (1994) Mutation of a mutL homolog in hereditary colon cancer. Science, 263, 1625-1629.
    • (1994) Science , vol.263 , pp. 1625-1629
    • Papadopoulos, N.1
  • 23
    • 0029069972 scopus 로고
    • Mutations of GTBP in genetically unstable cells
    • Papadopoulos,N. et al. (1995) Mutations of GTBP in genetically unstable cells. Science, 268, 1915-1917.
    • (1995) Science , vol.268 , pp. 1915-1917
    • Papadopoulos, N.1
  • 24
    • 0006171447 scopus 로고    scopus 로고
    • Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum
    • Jass,J.R. et al. (2000) Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum. Gut, 47, 43-49.
    • (2000) Gut , vol.47 , pp. 43-49
    • Jass, J.R.1
  • 25
    • 3242686837 scopus 로고    scopus 로고
    • BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
    • Kambara,T. et al. (2004) BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut, 53, 1137-1144.
    • (2004) Gut , vol.53 , pp. 1137-1144
    • Kambara, T.1
  • 26
    • 0036169109 scopus 로고    scopus 로고
    • Concordant CpG island methylation in hyperplastic polyposis
    • Chan,A.O. et al. (2002) Concordant CpG island methylation in hyperplastic polyposis. Am. J. Pathol., 160, 529-536.
    • (2002) Am. J. Pathol , vol.160 , pp. 529-536
    • Chan, A.O.1
  • 27
    • 0036144385 scopus 로고    scopus 로고
    • Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait
    • Halford,S. et al. (2002) Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait. Cancer Res., 62, 53-57.
    • (2002) Cancer Res , vol.62 , pp. 53-57
    • Halford, S.1
  • 28
    • 0030778613 scopus 로고    scopus 로고
    • Diagnostic microsatellite instability: Definition and correlation with mismatch repair protein expression
    • Dietmaier,W. et al. (1997) Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res., 57, 4749-4756.
    • (1997) Cancer Res , vol.57 , pp. 4749-4756
    • Dietmaier, W.1
  • 29
    • 17944383516 scopus 로고    scopus 로고
    • HMSH6 alterations in patients with microsatellite instability-low colorectal cancer
    • Parc,Y.R. et al. (2000) HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res., 60, 2225-2231.
    • (2000) Cancer Res , vol.60 , pp. 2225-2231
    • Parc, Y.R.1
  • 30
    • 0036168566 scopus 로고    scopus 로고
    • Low-level microsatellite instability in most colorectal carcinomas
    • Laiho,P. et al. (2002) Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62, 1166-1170.
    • (2002) Cancer Res , vol.62 , pp. 1166-1170
    • Laiho, P.1
  • 31
    • 0033043642 scopus 로고    scopus 로고
    • Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
    • Jass,J.R. et al. (1999) Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. J. Clin. Pathol., 52, 455-460.
    • (1999) J. Clin. Pathol , vol.52 , pp. 455-460
    • Jass, J.R.1
  • 32
    • 0035503498 scopus 로고    scopus 로고
    • High frequency of low-level microsatellite instability in early colorectal cancer
    • Kambara,T. et al. (2001) High frequency of low-level microsatellite instability in early colorectal cancer. Cancer Res. 61, 7743-7746.
    • (2001) Cancer Res , vol.61 , pp. 7743-7746
    • Kambara, T.1
  • 33
    • 19244370208 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
    • Esteller,M. et al. (2000) Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res., 60, 2368-2371.
    • (2000) Cancer Res , vol.60 , pp. 2368-2371
    • Esteller, M.1
  • 34
    • 0030054532 scopus 로고    scopus 로고
    • Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
    • Konishi,M. et al. (1996) Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. Gastroenterology, 111, 307-317.
    • (1996) Gastroenterology , vol.111 , pp. 307-317
    • Konishi, M.1
  • 35
    • 0033521962 scopus 로고    scopus 로고
    • Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability
    • Biden,K.G. et al. (1999) Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene, 18, 1245-1249.
    • (1999) Oncogene , vol.18 , pp. 1245-1249
    • Biden, K.G.1
  • 36
    • 33845318551 scopus 로고    scopus 로고
    • Characterization of a novel oncogenic K-ras mutation in colon cancer
    • Akagi,K. et al. (2007) Characterization of a novel oncogenic K-ras mutation in colon cancer. Biochem. Biophys. Res. Commun., 352 728-732.
    • (2007) Biochem. Biophys. Res. Commun , vol.352 , pp. 728-732
    • Akagi, K.1
  • 37
    • 0027302046 scopus 로고
    • Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors
    • Hamelin,R. et al. (1993) Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors. Oncogene, 8, 2213-2220.
    • (1993) Oncogene , vol.8 , pp. 2213-2220
    • Hamelin, R.1
  • 38
    • 0037194728 scopus 로고    scopus 로고
    • Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
    • Rajagopalan,H. et al. (2002) Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature, 418, 934.
    • (2002) Nature , vol.418 , pp. 934
    • Rajagopalan, H.1
  • 39
    • 33746861654 scopus 로고    scopus 로고
    • Do MSI-L sporadic colorectal tumors develop through "mild mutator pathway"?
    • Oliart,S. et al. (2006) Do MSI-L sporadic colorectal tumors develop through "mild mutator pathway"? Am. J. Clin. Oncol., 29, 364-370.
    • (2006) Am. J. Clin. Oncol , vol.29 , pp. 364-370
    • Oliart, S.1
  • 40
    • 0033864964 scopus 로고    scopus 로고
    • Phenotypic and molecular characteristics of hyperplastic polyposis
    • Rashid,A. et al. (2000) Phenotypic and molecular characteristics of hyperplastic polyposis. Gastroenterology, 119, 323-332.
    • (2000) Gastroenterology , vol.119 , pp. 323-332
    • Rashid, A.1
  • 41
    • 1842529801 scopus 로고    scopus 로고
    • Hyperplastic (serrated) polyps of the colorectum: Relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype
    • O'Brien,M.J. et al. (2004) Hyperplastic (serrated) polyps of the colorectum: Relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am. J. Surg. Pathol., 28, 423-434.
    • (2004) Am. J. Surg. Pathol , vol.28 , pp. 423-434
    • O'Brien, M.J.1
  • 42
    • 26944443724 scopus 로고    scopus 로고
    • Serrated adenoma of the colorectum and the DNA-methylator phenotype
    • Jass,J.R. (2005) Serrated adenoma of the colorectum and the DNA-methylator phenotype. Nat. Clin. Pract. Oncol., 2, 398-405.
    • (2005) Nat. Clin. Pract. Oncol , vol.2 , pp. 398-405
    • Jass, J.R.1
  • 43
    • 3242749886 scopus 로고    scopus 로고
    • Reduced MGMT activity in human colorectal adenomas is associated with K-ras GC-.AT transition mutations in a population exposed to methylating agents
    • Lees,N.P. et al. (2004) Reduced MGMT activity in human colorectal adenomas is associated with K-ras GC-.AT transition mutations in a population exposed to methylating agents. Carcinogenesis, 25, 1243-1247.
    • (2004) Carcinogenesis , vol.25 , pp. 1243-1247
    • Lees, N.P.1
  • 44
    • 19544392006 scopus 로고    scopus 로고
    • Halford,S. et al. (2005) O(6)-methylguanine methyltransferase in colorectal cancers: Detection of mutations, loss of expression, and weak association with G:C.>A:T transitions. Gut, 54, 797-802.
    • Halford,S. et al. (2005) O(6)-methylguanine methyltransferase in colorectal cancers: Detection of mutations, loss of expression, and weak association with G:C.>A:T transitions. Gut, 54, 797-802.
  • 45
    • 0035874892 scopus 로고    scopus 로고
    • Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis
    • Esteller,M. et al. (2001) Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis. Cancer Res., 6, 4689-4692.
    • (2001) Cancer Res , vol.6 , pp. 4689-4692
    • Esteller, M.1
  • 46
    • 0035060624 scopus 로고    scopus 로고
    • Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status
    • Michael-Robinson,J.M. et al. (2001) Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status. Gut, 48, 360-366.
    • (2001) Gut , vol.48 , pp. 360-366
    • Michael-Robinson, J.M.1
  • 47
    • 0034892805 scopus 로고    scopus 로고
    • Proliferation, apoptosis, and survival in high-level microsatellite instability sporadic colorectal cancer
    • Michael-Robinson,J.M. et al. (2001) Proliferation, apoptosis, and survival in high-level microsatellite instability sporadic colorectal cancer. Clin. Cancer Res., 7, 2347-2356.
    • (2001) Clin. Cancer Res , vol.7 , pp. 2347-2356
    • Michael-Robinson, J.M.1
  • 48
    • 20244368982 scopus 로고    scopus 로고
    • Low microsatellite instability is associated with poor prognosis in stage C colon cancer
    • Kohonen-Corish,M.R. et al. (2005) Low microsatellite instability is associated with poor prognosis in stage C colon cancer. J. Clin. Oncol., 23, 2318-2324.
    • (2005) J. Clin. Oncol , vol.23 , pp. 2318-2324
    • Kohonen-Corish, M.R.1
  • 49
    • 19944374437 scopus 로고    scopus 로고
    • Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma
    • Wright,C.M. et al. (2005) Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma. Gut, 54, 103-108.
    • (2005) Gut , vol.54 , pp. 103-108
    • Wright, C.M.1
  • 50
    • 0027412665 scopus 로고
    • Prognostic significance of K-ras mutations in colorectal carcinoma
    • Benhattar,J. et al. (1993) Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology, 104, 1044-1048.
    • (1993) Gastroenterology , vol.104 , pp. 1044-1048
    • Benhattar, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.