Optimal expiratory volume profile in tidal liquid ventilation under steady state conditions, based on a symmetrical lung model

ASAIO Journal

Volumn 55, Issue 1, 2009, Pages 63-72

  Robert, Raymond ^a   Micheau, Philippe ^a   Walti, Hervé ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOKED FLOW; EXPERIMENTAL DATA; FLOW LIMITATIONS; FLOW MECHANISMS; GAS EXCHANGE; LIQUID VENTILATIONS; LUNG MODEL; MODEL RESULTS; NUMERICAL MODELS; PARAMETER VARIATION; PERFLUOROCHEMICALS; PRACTICAL RECOMMENDATION; PRESSURE LOSS; RESIDUAL CAPACITY; STEADY-STATE CONDITION; TIDAL VOLUME; TIME CONSTANTS;

AC GENERATOR MOTORS; BIOLOGICAL ORGANS; LIQUIDS; NUMERICAL METHODS; OPTICAL FILTERS; OPTIMIZATION; SENSITIVITY ANALYSIS;

VENTILATION;

AIRFLOW; AIRWAY; AIRWAY PRESSURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPIRATORY RESERVE VOLUME; FORCED EXPIRATION; GAS EXCHANGE; LAMB; LIQUID VENTILATION; LUNG; LUNG COLLAPSE; NEWBORN; NONHUMAN; RISK FACTOR; STEADY STATE; TIDAL VOLUME; BIOLOGICAL MODEL; HUMAN; INFANT; PHYSIOLOGY;

HUMANS; INFANT; LIQUID VENTILATION; LUNG; MODELS, BIOLOGICAL;

EID: 62449293208     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAT.0b013e3181911821     Document Type: Article

References (47)

1. Clark LC Jr, Gollan F: Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure. Science 152: 1755-1756, 1996.
2. Hirschl RB, Tooley R, Parent AC, et al: Improvement of gas exchange, pulmonary function, and lung injury with partial liquid ventilation. A study model in a setting of severe respiratory failure. Chest 108: 500-508, 1995.
3. Hirschl RB, Tooley R, Parent A, et al: Evaluation of gas exchange, pulmonary compliance, and lung injury during total and partial liquid ventilation in the acute respiratory distress syndrome. Crit Care Med 24: 1001-1008, 1996.
4. Rudiger M, Some M, Jarstrand C, et al: Influence of partial liquid ventilation on bacterial growth and alveolar expansion in newborn rabbits with group B-streptococcal pneumonia. Pediatr Res 54: 808-813, 2003.
5. Foust R III, Tran NN, Cox C, et al: Liquid assisted ventilation: An alternative ventilatory strategy for acute meconium aspiration injury. Pediatr Pulmonol 21: 316-322, 1996.
6. Richman PS, Wolfson MR, Shaffer TH: Lung lavage with oxygenated perfluorochemical liquid in acute lung injury. Crit Care Med 21: 768-774, 1993.
7. Rotta AT, Steinhorn DM: Partial liquid ventilation reduces pulmonary neutrophil accumulation in an experimental model of systemic endotoxemia and acute lung injury. Crit Care Med 26: 1707-1715, 1998.
8. Cox C, Stavis RL, Wolfson MR, Shaffer TH: Long-term tidal liquid ventilation in premature lambs: Physiologic biochemical and histological correlates. Biol Neonate 84: 232-242, 2003.
9. Dani C, Costantino ML, Martelli E, et al: Perfluorocarbons attenuate oxidative lung damage. Pediatr Pulmonol 36: 322-329, 2003.
10. Hirschl RB, Croce M, Gore D, et al: Prospective, randomized, controlled pilot study of partial liquid ventilation in adult acute respiratory distress syndrome. Am J Respir Crit Care Med 165: 781-787, 2002.
11. Degraeuwe PL, Vos GD, Geskens GG, et al: Effect of perfluorochemical liquid ventilation on cardiac output and blood pres- sure variability in neonatal piglets with respiratory insufficiency. Pediatr Pulmonol 30: 114-124, 2000.
12. Cox CA, Fox WW, Wolfson CM, Shaffer TH: Liquid ventilation: Gas exchange, perfluorochemical uptake, and biodistribution in an acute lung injury. Pediatr Crit Care Med 3: 288-296, 2002.
13. Baba Y, Taenaka Y, Akagi H, et al: A volume-controlled liquid ventilator with pressure-limit mode: Imperative expiratory control. Artif Organs 20: 1052-1056, 1996.
14. Baba Y, Brant D, Brah SS, et al: Assessment of the development of choked flow during total liquid ventilation. Crit Care Med 32: 201-208, 2004.
15. Robert R, Micheau P, Walti H: A supervisor for volume-controlled tidal liquid ventilator using independent piston pumps. Biomed Signal Proc Control 2: 267-274, 2007.
16. 2 elimination. Pediatr Res 24: 291-296, 1988.
17. Meinhardt JP, Ashton BA, Annich GM, et al: The dependency of expiratory airway collapse on pump system and flow rate in liquid ventilated rabbits. Eur J Med Res 8: 212-220, 2003.
18. Bull JL, Reickert CA, Tredici S, et al: Flow limitation in liquid-filled lungs: Effects of liquid properties. J Biomech Eng 127: 630-636, 2005.
19. Foley DS, Brah R, Bull JL, et al: Total liquid ventilation: Dynamic airway pressure and the development of expiratory flow limitation. ASAIO J 50: 485-490, 2004.
20. Komori E, Tredici S, Bull JL, et al: Expiratory flow limitation during gravitational drainage of perfluorocarbons from liquid-filled lungs. ASAIO J 51: 795-801, 2005.
21. Elad D, Kamm RD, Shapiro AH: Mathematical simulation of forced expiration. J Appl Physiol 65: 14-25, 1988.
22. Lambert RK, Wilson TA, Hyatt RE, Rodarte JR: A computational model for expiratory flow. J Appl Physiol 52: 44-56, 1982.
23. Polak AG: A forward model for maximum expiration. Comput Biol Med 28: 613-625, 1998.
24. Corno C, Fiore GB, Costantino ML: A mathematical model of neonatal tidal liquid ventilation integrating airway mechanics and gas transfer phenomena. IEEE Trans Biomed Eng 51: 604-611, 2004.
25. Costantino ML, Fiore GB: A model of neonatal tidal liquid ventilation mechanics. Med Eng Phys 23: 457-471, 2001.
26. Tarczy-Hornoch P, Hildebrandt J, Jackson JC: Gravitational effects on volume distribution in a model of partial and total liquid ventilation. Respir Physiol 120: 125-138, 2000.
27. Horsfield K, Dart G, Olson DE, et al: Models of the human bronchial tree. J Appl Physiol 31: 207-217, 1971.
28. Weibel ER: Morphometry of the Human Lung. Berlin, Germany, Springer, 1963.
29. Hyatt RE, Wilson TA, Bar-Yishay E: Prediction of maximal expiratory flow in excised human lungs. J Appl Physiol 48: 991-998, 1980.
30. Munson BR, Young DF, Okiishi TH: Fundamentals of Fluid Mechanics, 3rd ed. New York, Wiley, 1998.
31. Dawson SV, Elliott EA: Wave-speed limitation on expiratory flow-a unifying concept. J Appl Physiol 43: 498-515, 1977.
32. Dawson SV, Elliott EA: Use of the choke point in the prediction of flow limitation in elastic tubes. Fed Proc 39: 2765-2770, 1980.
33. Isabey D, Chang HK: A model study of flow dynamics in human central airways. Part II: Secondary flow velocities. Respir Physiol 49: 97-113, 1982.
34. Schroter RC, Sudlow MF: Flow patterns in models of the human bronchial airways. Respir Physiol 7: 341-355, 1969.
35. Zhao Y, Brunskill CT, Lieber BB: Inspiratory and expiratory steady flow analysis in a model symmetrically bifurcating airway. J Biomech Eng 119: 52-58, 1997.
36. Collins JM, Shapiro AH, Kimmel E, Kamm RD: The steady expiratory pressure-flow relation in a model pulmonary bifurcation. J Biomech Eng 115: 299-305, 1993.
37. Reynolds DB: Steady expiratory flow-pressure relationship in a model of the human bronchial tree. J Biomech Eng 104: 153-158, 1982.
38. Venegas JG, Simon RS, Harris BA: A comprehensive equation for the pulmonary pressure-volume curve. JAP 84: 389-395, 1998.
39. Curtis SE, P Furhman B, Howland DF: Airway and alveolar pres- sures during perfluorocarbon breathing in infant lambs. JAP 68: 2322-2328, 1990.
40. Larrabe JL, Alvarez FJ, Cuesta EG, et al: Development of a time-cycled volume-controlled pressure-limited respirator and lung mechanics system for total liquid ventilation. IEEE Trans Biomed Eng 48: 1134-1144, 2001.
41. Hughes JM, Hoppin FG Jr, Mead J: Effect of lung inflation on bronchial length and diameter in excised lungs. J Appl Physiol 32: 25-35, 1972.
42. Lambert RK, Castile RG, Tepper RS: Model of forced expiratory flows and airway geometry in infants. J Appl Physiol 96: 688-692, 2004.
43. Lambert RK: Sensitivity and specificity of the computational model for maximal expiratory flow. J Appl Physiol 57: 958-970, 1984.
44. Bull JL, Foley DS, Bagnoli P, et al: Location of flow limitation in liquid-filled rabbit lungs. ASAIO J 51: 781-788, 2005.
45. Kreyszig E: Advanced Engineering Mathematics, 7th ed. New York, Wiley, 1993.
46. Tredici S, Komori E, Funakubo A, et al: A prototype of a liquid ventilator using a novel hollow-fiber oxygenator in a rabbit model. Crit Care Med 32: 2104-2109, 2004.
47. Robert R, Micheau P, Cyr S, et al: A prototype of volume-controlled tidal liquid ventilator using independent piston pumps. ASAIO J 52: 638-645, 2006.