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Volumn 76, Issue 5, 2009, Pages 301-310

The role of UFT in metastatic colorectal cancer

Author keywords

5 FU combination therapy; Colorectal cancer; Irinotecan; Oxaliplatin; UFT

Indexed keywords

CAPECITABINE; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; MITOMYCIN C; OXALIPLATIN; TEGAFUR; UFT; URACIL;

EID: 62449253891     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000209334     Document Type: Review
Times cited : (21)

References (60)
  • 4
    • 0027461840 scopus 로고
    • Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer
    • Scheithauer W, Rosen H, Kornek GV, Sebesta C, Depisch D: Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer. BMJ 1993; 306: 752-756.
    • (1993) BMJ , vol.306 , pp. 752-756
    • Scheithauer, W.1    Rosen, H.2    Kornek, G.V.3    Sebesta, C.4    Depisch, D.5
  • 7
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, Findlay BP, Pitot HC, Alberts SR: A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004; 22: 23-30.
    • (2004) J Clin Oncol , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3    Fuchs, C.S.4    Ramanathan, R.K.5    Williamson, S.K.6    Findlay, B.P.7    Pitot, H.C.8    Alberts, S.R.9
  • 8
    • 67349250873 scopus 로고    scopus 로고
    • Peeters M, Raoul JL, van Laethem JL, Rougier P, Brezault C, Husseini F, Cals L, Zubel A, Vedovato JC: Cetuximab in combination with irinotecan/5- fluorouracil (5-FU)/folinic acid (FA) (FOLFIRI) in the first-line treatment of metastatic colorectal cancer (mCRC). Eur J Cancer Suppl 2005; 3: 188(abstract 664).
    • Peeters M, Raoul JL, van Laethem JL, Rougier P, Brezault C, Husseini F, Cals L, Zubel A, Vedovato JC: Cetuximab in combination with irinotecan/5- fluorouracil (5-FU)/folinic acid (FA) (FOLFIRI) in the first-line treatment of metastatic colorectal cancer (mCRC). Eur J Cancer Suppl 2005; 3: 188(abstract 664).
  • 9
    • 33644697486 scopus 로고    scopus 로고
    • Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
    • Folprecht G, Lutz MP, Schöffski P, Seufferlein T, Nolting A, Pollert P, Köhne CH: Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol 2006; 17: 450-456.
    • (2006) Ann Oncol , vol.17 , pp. 450-456
    • Folprecht, G.1    Lutz, M.P.2    Schöffski, P.3    Seufferlein, T.4    Nolting, A.5    Pollert, P.6    Köhne, C.H.7
  • 10
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson AB III: Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007; 25: 1539-1544.
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 12
    • 0345596364 scopus 로고    scopus 로고
    • Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factors
    • Meta-Analysis Group in Cancer
    • Meta-Analysis Group in Cancer: Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. J Clin Oncol 1998; 16: 3537-3541.
    • (1998) J Clin Oncol , vol.16 , pp. 3537-3541
  • 14
    • 0141973788 scopus 로고    scopus 로고
    • Venous thromboembolism associated with long-term use of central venous catheters in cancer patients
    • Verso M, Agnelli G: Venous thromboembolism associated with long-term use of central venous catheters in cancer patients. J Clin Oncol 2003; 21: 3665-3675.
    • (2003) J Clin Oncol , vol.21 , pp. 3665-3675
    • Verso, M.1    Agnelli, G.2
  • 15
    • 21344449406 scopus 로고    scopus 로고
    • Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer
    • National Institute for Clinical Excellence:, May
    • National Institute for Clinical Excellence: Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer. Technology Appraisal 61, May 2003.
    • (2003) Technology Appraisal , vol.61
  • 17
    • 33750179595 scopus 로고    scopus 로고
    • Patient preference for oral or intravenous chemotherapy: A randomised cross-over trial comparing capecitabine and Nordic fluorouracil/leucovorin in patients with colorectal cancer
    • Pfeiffer P, Mortensen JP, Bjerregaard B, Eckhoff L, Schønnemann K, Sandberg E, Aabo K, Jakobsen A: Patient preference for oral or intravenous chemotherapy: a randomised cross-over trial comparing capecitabine and Nordic fluorouracil/leucovorin in patients with colorectal cancer. Eur J Cancer 2006; 42: 2738-2743.
    • (2006) Eur J Cancer , vol.42 , pp. 2738-2743
    • Pfeiffer, P.1    Mortensen, J.P.2    Bjerregaard, B.3    Eckhoff, L.4    Schønnemann, K.5    Sandberg, E.6    Aabo, K.7    Jakobsen, A.8
  • 18
    • 0031691506 scopus 로고    scopus 로고
    • Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N 1 -(2-tetrahydrofuryl)- 5-fluorouracil
    • Ho DH, Pazdur R, Covington W, Brown N, Huo YY, Lassere Y, Kuritani J: Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N 1 -(2-tetrahydrofuryl)- 5-fluorouracil. Clin Cancer Res 1998; 4: 2085-2088.
    • (1998) Clin Cancer Res , vol.4 , pp. 2085-2088
    • Ho, D.H.1    Pazdur, R.2    Covington, W.3    Brown, N.4    Huo, Y.Y.5    Lassere, Y.6    Kuritani, J.7
  • 19
    • 0019471403 scopus 로고
    • Studies on combination therapy with 1-(tetrahydro-2-furanyl)-5- fluorouracil plus uracil. Effects of uracil on in vitro metabolism of 1-(tetrahydro-2-furanyl)- 5-fluorouracil and 5-fluorouracil
    • Unemi N, Takeda S: Studies on combination therapy with 1-(tetrahydro-2-furanyl)-5- fluorouracil plus uracil. Effects of uracil on in vitro metabolism of 1-(tetrahydro-2-furanyl)- 5-fluorouracil and 5-fluorouracil. Chemotherapy 1981; 29: 176-184.
    • (1981) Chemotherapy , vol.29 , pp. 176-184
    • Unemi, N.1    Takeda, S.2
  • 20
    • 0019463497 scopus 로고
    • Studies on combination therapy with 1-(tetrahydro-2-furany1)-5-fluorouracil plus uracil. Effect of co-administration of uracil on the antitumor activity of 1-(tetrahydro- 2-furanyl)-5-fluorouracil and the level of 5-fluorouracil in AH-130-bearing rats
    • Unemi N, Takeda S, Tajima K, Kawaguchi Y, Yasuda A: Studies on combination therapy with 1-(tetrahydro-2-furany1)-5-fluorouracil plus uracil. Effect of co-administration of uracil on the antitumor activity of 1-(tetrahydro- 2-furanyl)-5-fluorouracil and the level of 5-fluorouracil in AH-130-bearing rats. Chemotherapy 1981; 29: 164-175.
    • (1981) Chemotherapy , vol.29 , pp. 164-175
    • Unemi, N.1    Takeda, S.2    Tajima, K.3    Kawaguchi, Y.4    Yasuda, A.5
  • 23
    • 0036730401 scopus 로고    scopus 로고
    • Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/ leucovorin for the treatment of metastatic colorectal cancer
    • Yang TS, Wang JY, Tang R, Hsu KC, Chen JS: Oral uracil/ftorafur (UFT) plus leucovorin as first-line chemotherapy and salvage therapy with weekly high-dose 5-fluorouracil/ leucovorin for the treatment of metastatic colorectal cancer. Jpn J Clin Oncol 2002; 32: 352-357.
    • (2002) Jpn J Clin Oncol , vol.32 , pp. 352-357
    • Yang, T.S.1    Wang, J.Y.2    Tang, R.3    Hsu, K.C.4    Chen, J.S.5
  • 24
    • 0035342205 scopus 로고    scopus 로고
    • Aranda E, Anton-Torres A, Sastre J, Navarro M, Rivera F, Carrato A, Breton JJ, Aparicio J, Fernandez-Martos C, Diaz-Rubio E; Spanish Cooperative Group for Gastrointestinal Tumor Therapy: Tegafur and uracil plus leucovorin in advanced colorectal cancer: a phase II trial. Clin Colorectal Cancer 2001; 1: 43-@ 46.
    • Aranda E, Anton-Torres A, Sastre J, Navarro M, Rivera F, Carrato A, Breton JJ, Aparicio J, Fernandez-Martos C, Diaz-Rubio E; Spanish Cooperative Group for Gastrointestinal Tumor Therapy: Tegafur and uracil plus leucovorin in advanced colorectal cancer: a phase II trial. Clin Colorectal Cancer 2001; 1: 43-@ 46.
  • 25
    • 36849089518 scopus 로고    scopus 로고
    • Phase II study of uracil-tegafur with leucovorin in elderly ( 6 75 years old) patients with colorectal cancer: ECOG 1299
    • Hochster HS, Luo W, Popa EC, Lyman BT, Mulcahy M, Beatty PA, Benson AB: Phase II study of uracil-tegafur with leucovorin in elderly ( 6 75 years old) patients with colorectal cancer: ECOG 1299. J Clin Oncol 2007; 25: 5397-5402.
    • (2007) J Clin Oncol , vol.25 , pp. 5397-5402
    • Hochster, H.S.1    Luo, W.2    Popa, E.C.3    Lyman, B.T.4    Mulcahy, M.5    Beatty, P.A.6    Benson, A.B.7
  • 26
    • 0036727089 scopus 로고    scopus 로고
    • Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Carmichael J, Popiela T, Radstone D, Falk S, Borner M, Oza A, Skovsgaard T, Munier S, Martin C: Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2002; 20: 3617-3627.
    • (2002) J Clin Oncol , vol.20 , pp. 3617-3627
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3    Falk, S.4    Borner, M.5    Oza, A.6    Skovsgaard, T.7    Munier, S.8    Martin, C.9
  • 29
    • 67349113920 scopus 로고    scopus 로고
    • Xeloda Summary of Product Characteristics (available at http://emc.medicines.org.uk/ emc/assets/c/html/displaydoc.asp?documentid= 4619).
    • Xeloda Summary of Product Characteristics (available at http://emc.medicines.org.uk/ emc/assets/c/html/displaydoc.asp?documentid= 4619).
  • 30
    • 67349199627 scopus 로고    scopus 로고
    • UFT Summary of Product Characteristics (available at http://emc. medicines.org.uk/ emc/assets/c/html/displaydoc.asp?documentid= 4399).
    • UFT Summary of Product Characteristics (available at http://emc. medicines.org.uk/ emc/assets/c/html/displaydoc.asp?documentid= 4399).
  • 34
    • 25444443120 scopus 로고    scopus 로고
    • Phase II trial of oxaliplatin and tegafur/uracil and oral folinic acid for advanced or metastatic colorectal cancer in elderly patients
    • Rosati G, Cordio S, Tucci A, Blanco G, Bordonaro R, Reggiardo G, Manzione L: Phase II trial of oxaliplatin and tegafur/uracil and oral folinic acid for advanced or metastatic colorectal cancer in elderly patients. Oncology 2005; 69: 122-129.
    • (2005) Oncology , vol.69 , pp. 122-129
    • Rosati, G.1    Cordio, S.2    Tucci, A.3    Blanco, G.4    Bordonaro, R.5    Reggiardo, G.6    Manzione, L.7
  • 38
    • 67349239777 scopus 로고    scopus 로고
    • Alternating irinotecan with oxaliplatin combined with UFT plus leucovorin (LV) (SCOUT) in patients with advanced colorectal cancer (ACRC): A phase I/II study
    • abstract 4084
    • Sheikh HY, Valle JW, Palmer K, Wilson G, Sjursen A, Craven O, Swindell R, Saunders MP: Alternating irinotecan with oxaliplatin combined with UFT plus leucovorin (LV) (SCOUT) in patients with advanced colorectal cancer (ACRC): a phase I/II study. J Clin Oncol 2007; 25(suppl):abstract 4084.
    • (2007) J Clin Oncol , vol.25 , Issue.SUPPL.
    • Sheikh, H.Y.1    Valle, J.W.2    Palmer, K.3    Wilson, G.4    Sjursen, A.5    Craven, O.6    Swindell, R.7    Saunders, M.P.8
  • 39
    • 67349279220 scopus 로고    scopus 로고
    • Bennouna J, Faroux R, François E, Ligeza C, El Hannani C, Perrier H, Jacob J, Desseigne F, Perrocheau G, Douillard JY: CETUFTIRI, a new combination of UFT with leucovorin (LV), irinotecan, and cetuximab as first-line treatment for patients (pts) with unresectable metastatic colorectal cancer (mCRC): preliminary results from a multicenter phase II trial. J Clin Oncol 2007; 25(suppl):abstract 4087.
    • Bennouna J, Faroux R, François E, Ligeza C, El Hannani C, Perrier H, Jacob J, Desseigne F, Perrocheau G, Douillard JY: CETUFTIRI, a new combination of UFT with leucovorin (LV), irinotecan, and cetuximab as first-line treatment for patients (pts) with unresectable metastatic colorectal cancer (mCRC): preliminary results from a multicenter phase II trial. J Clin Oncol 2007; 25(suppl):abstract 4087.
  • 41
    • 20044384354 scopus 로고    scopus 로고
    • Swiss Group for Clinical Cancer Research (SAKK): A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity
    • Borner MM, Bernhard J, Dietrich D, Popescu R, Wernli M, Saletti P, Rauch D, Herrmann R, Koeberle D, Honegger H, Brauchli P, Lanz D, Roth AD; Swiss Group for Clinical Cancer Research (SAKK): A randomized phase II trial of capecitabine and two different schedules of irinotecan in first-line treatment of metastatic colorectal cancer: efficacy, quality-of-life and toxicity. Ann Oncol 2005; 16: 282-288.
    • (2005) Ann Oncol , vol.16 , pp. 282-288
    • Borner, M.M.1    Bernhard, J.2    Dietrich, D.3    Popescu, R.4    Wernli, M.5    Saletti, P.6    Rauch, D.7    Herrmann, R.8    Koeberle, D.9    Honegger, H.10    Brauchli, P.11    Lanz, D.12    Roth, A.D.13
  • 43
    • 33645309877 scopus 로고    scopus 로고
    • FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs. FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
    • Souglakos J, Androulakis N, Syrigos K, Polyzos A, Ziras N, Athanasiadis A, Kakolyris S, Tsousis S, Kouroussis Ch, Vamvakas L, Kalykaki A, Samonis G, Mavroudis D, Georgoulias V: FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs. FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 2006; 94: 798-805.
    • (2006) Br J Cancer , vol.94 , pp. 798-805
    • Souglakos, J.1    Androulakis, N.2    Syrigos, K.3    Polyzos, A.4    Ziras, N.5    Athanasiadis, A.6    Kakolyris, S.7    Tsousis, S.8    Kouroussis, C.9    Vamvakas, L.10    Kalykaki, A.11    Samonis, G.12    Mavroudis, D.13    Georgoulias, V.14
  • 45
    • 34948892881 scopus 로고    scopus 로고
    • Díaz-Rubio E, Tabernero J, Gómez-España A, Massutí B, Sastre J, Chaves M, Abad A, Carrato A, Queralt B, Reina JJ, Maurel J, González-Flores E, Aparicio J, Rivera F, Losa F, Aranda E; Spanish Cooperative Group for the Treatment of Digestive Tumors Trial: Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol 2007; 25: 4224-4230.
    • Díaz-Rubio E, Tabernero J, Gómez-España A, Massutí B, Sastre J, Chaves M, Abad A, Carrato A, Queralt B, Reina JJ, Maurel J, González-Flores E, Aparicio J, Rivera F, Losa F, Aranda E; Spanish Cooperative Group for the Treatment of Digestive Tumors Trial: Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol 2007; 25: 4224-4230.
  • 49
    • 33749840555 scopus 로고    scopus 로고
    • Cetuximab + capecitabine + irinotecan (CCI) versus cetuximab + capecitabine + oxaliplatin (CCO) as first line therapy for patients with metastatic colorectal cancer (CRC): Preliminary results of a randomized phase II trial of the AIO CRC Study Group
    • abstract 3550
    • Heinemann V, Fischer von Weikersthal L, Moosmann N, Vehling-Kaiser U, Stauch M, Oruzio D, Schulze M, Walther J, Weiss J, Dietzfelbinger H: Cetuximab + capecitabine + irinotecan (CCI) versus cetuximab + capecitabine + oxaliplatin (CCO) as first line therapy for patients with metastatic colorectal cancer (CRC): preliminary results of a randomized phase II trial of the AIO CRC Study Group. J Clin Oncol 2006; 24(suppl): abstract 3550.
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL.
    • Heinemann, V.1    Fischer von Weikersthal, L.2    Moosmann, N.3    Vehling-Kaiser, U.4    Stauch, M.5    Oruzio, D.6    Schulze, M.7    Walther, J.8    Weiss, J.9    Dietzfelbinger, H.10
  • 50
    • 67349124815 scopus 로고    scopus 로고
    • Sizer B, Makris A, Barone C, Bordonaro R, Hausmaninger H, Steger G, Aloe A, Peeters O, Donato B: QoL and resource use analysis of tegafur-uracil/LV or 5-FU/LV in first-line metastatic colorectal cancer (mCRC): final results of a multicenter phase II study. J Clin Oncol 2006; 24(suppl):abstract 3631.
    • Sizer B, Makris A, Barone C, Bordonaro R, Hausmaninger H, Steger G, Aloe A, Peeters O, Donato B: QoL and resource use analysis of tegafur-uracil/LV or 5-FU/LV in first-line metastatic colorectal cancer (mCRC): final results of a multicenter phase II study. J Clin Oncol 2006; 24(suppl):abstract 3631.
  • 51
    • 0034231616 scopus 로고    scopus 로고
    • Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management
    • Nagore E, Insa A, Sanmartin O: Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management. Am J Clin Dermatol 2000; 1: 225-234.
    • (2000) Am J Clin Dermatol , vol.1 , pp. 225-234
    • Nagore, E.1    Insa, A.2    Sanmartin, O.3
  • 52
    • 0141993698 scopus 로고    scopus 로고
    • A cost comparison of oral tegafur plus uracil/ folinic acid and parenteral fluorouracil for colorectal cancer in Canada
    • Maroun JA, Asche C, Romeyer F, Mukherjee J, Cripps C, Oza A, Skillings J, Letarte J: A cost comparison of oral tegafur plus uracil/ folinic acid and parenteral fluorouracil for colorectal cancer in Canada. Pharmacoeconomics 2003; 21: 1039-1051.
    • (2003) Pharmacoeconomics , vol.21 , pp. 1039-1051
    • Maroun, J.A.1    Asche, C.2    Romeyer, F.3    Mukherjee, J.4    Cripps, C.5    Oza, A.6    Skillings, J.7    Letarte, J.8
  • 55
    • 67349195411 scopus 로고    scopus 로고
    • Oxaliplatin, UFT and oral leucovorin combination chemotherapy in 5-FU refractory colorectal carcinoma: A phase II study
    • abstract 3774
    • Ryoo H-M, Bae SH, Lee HI, Lee JL, Lee KH, Hyun M, Park KU: Oxaliplatin, UFT and oral leucovorin combination chemotherapy in 5-FU refractory colorectal carcinoma: a phase II study. J Clin Oncol 2004; 22(suppl): abstract 3774.
    • (2004) J Clin Oncol , vol.22 , Issue.SUPPL.
    • Ryoo, H.-M.1    Bae, S.H.2    Lee, H.I.3    Lee, J.L.4    Lee, K.H.5    Hyun, M.6    Park, K.U.7
  • 56
    • 0035032625 scopus 로고    scopus 로고
    • Krulik M; for the Oncology Multidisciplinary Research Group (GERCOR): High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7)
    • Maindrault-Goebel F, de Gramont A, Louvet C, André T, Carola E, Mabro M, Artu P, Gilles V, Lotz JP, Izrael V, Krulik M; for the Oncology Multidisciplinary Research Group (GERCOR): High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7). Eur J Cancer 2001; 37: 1000-1005.
    • (2001) Eur J Cancer , vol.37 , pp. 1000-1005
    • Maindrault-Goebel, F.1    de Gramont, A.2    Louvet, C.3    André, T.4    Carola, E.5    Mabro, M.6    Artu, P.7    Gilles, V.8    Lotz, J.P.9    Izrael, V.10
  • 57
    • 27644584203 scopus 로고    scopus 로고
    • Oxaliplatin, folinic acid and 5-fluorouracil (FOLFOX- 4) combination chemotherapy as second- line treatment in advanced colorectal cancer patients with irinotecan failure: A Korean single-center experience
    • Park SH, Sung JY, Han SH, Baek JH, Oh JH, Bang SM, Cho EK, Shin DB, Lee JH: Oxaliplatin, folinic acid and 5-fluorouracil (FOLFOX- 4) combination chemotherapy as second- line treatment in advanced colorectal cancer patients with irinotecan failure: a Korean single-center experience. Jpn J Clin Oncol 2005; 35: 531-535.
    • (2005) Jpn J Clin Oncol , vol.35 , pp. 531-535
    • Park, S.H.1    Sung, J.Y.2    Han, S.H.3    Baek, J.H.4    Oh, J.H.5    Bang, S.M.6    Cho, E.K.7    Shin, D.B.8    Lee, J.H.9


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