Discriminative stimulus properties of naloxone in Long-Evans rats: Assessment with the conditioned taste aversion baseline of drug discrimination learning

Psychopharmacology

Volumn 203, Issue 2, 2009, Pages 421-429

  Davis, Catherine M ^a   Stevenson, Glenn W ^b   Cañadas, Fernando ^a   Ullrich, Thomas ^c   Rice, Kenner C ^c   Riley, Anthony L ^a  

^a AMERICAN UNIVERSITY   (United States)

^b UNIVERSITY OF NEW ENGLAND   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

CTA; Drug discrimination; MR2266; Naloxone; Naltrexone; Naltrexone methobromide; Naltrindole; Opiate na ve; Rat

Indexed keywords

17 METHYLNALTREXONE BROMIDE; 5,9 DIETHYL 2 (3 FURYLMETHYL) 2' HYDROXY 6,7 BENZOMORPHAN; DELTA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALOXONE; NALTREXONE; NALTRINDOLE;

ANIMAL EXPERIMENT; ARTICLE; AVERSION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DRUG DISCRIMINATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FEMALE; LONG EVANS RAT; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANIMALS; DISCRIMINATION (PSYCHOLOGY); DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; NALOXONE; NARCOTIC ANTAGONISTS; RATS; RATS, LONG-EVANS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; SACCHARIN; TASTE;

EID: 62449211297     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-008-1233-5     Document Type: Article

References (47)

1. A Bechara D van der Kooy 1987 Kappa receptors mediate the peripheral aversive effects of opiates Pharmacol Biochem Behav 28 227 233
2. A Bechara KA Zito D van der Kooy 1987 Peripheral receptors mediate the aversive conditioning effects of morphine in the rat Pharmacol Biochem Behav 28 219 225
3. DR Brown LI Goldberg 1985 The use of quaternary antagonists in opiate research Neuropharmacology 24 181 191
4. DR Brown SG Holtzman 1981 Opiate antagonists: central sites of action in suppressing water intake of the rat Brain Res 221 432 436
5. RB Carter JD Leander 1982 Discriminative stimulus properties of naloxone Psychopharmacology (Berl) 77 4 305 308
6. SR Chen HL Pan 2006 Blocking mu opioid receptors in the spinal cord prevents the analgesic action by subsequent systemic opioids Brain Res 1081 1 119 125
7. FC Colpaert PA Janssen 1984 Agonist and antagonist effects of prototype opiate drugs in rats discriminating fentanyl from saline: characteristics of partial generalization J Pharmacol Exp Ther 230 193 199
8. MS Fanselow DJ Calcagnetti FJ Helmstetter 1989 Modulation of appetitively and aversively motivated behavior by the kappa opioid antagonist MR2266 Behav Neurosci 103 663 672
9. SD Grabus ST Smurthwaite AL Riley 1999 Nalorphine's ability to substitute for morphine in a drug discrimination procedure is a function of training dose Pharmacol Biochem Behav 63 481 488
10. SG Holtzman 1985 Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs J Pharmacol Exp Ther 233 80 86
11. SG Holtzman GF Steinfels 1994 Antagonism of the discriminative stimulus effects of the kappa-opioid agonist spiradoline Psychopharmacology (Berl) 116 243 248
12. MJ Katovich JW Simpkins J O'Meara 1986 Effects of opioid antagonists and their quaternary analogs on temperature changes in morphine-dependent rats Life Sci 39 1845 1854
13. MA Kautz B Geter SA McBride JP Mastropaolo AL Riley 1989 Naloxone as a stimulus for drug discrimination learning Drug Dev Res 16 317 326
14. TC Kirkham SJ Cooper 1988 Naloxone attenuation of sham feeding is modified by manipulation of sucrose concentration Physiol Behav 44 491 494
15. GF Koob HO Pettit A Ettenberg FE Bloom 1994 Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat J Pharmacol Exp Ther 229 481 486
16. Lal H, Miksic S, McCarten M (1978) A comparison of discriminative stimuli produced by naloxone, cyclazocine and morphine in the rat. In: Colpaert FC, Rosecrans JA (eds) Stimulus properties of drugs: ten years of progress. Elsevier, Amsterdam, pp 177-180
17. FM Leslie 1987 Methods used for the study of opioid receptors Pharmacol Rev 39 197 249
18. AS Levine CM Kotz BA Gosnell 2003 Sugars: hedonic aspects, neuroregulation, and energy balance Am J Clin Nutr 78 suppl 834S 842S
19. KW Locke SG Holtzman 1985 Characterization of the discriminative stimulus effects of centrally administered morphine in the rat Psychopharmacology (Berl) 87 1 6
20. JP Mastropaolo KH Moskowitz RJ Dacanay AL Riley 1989 Conditioned taste aversions as a behavioral baseline for a drug discrimination learning: an assessment with phencyclidine Pharmacol Biochem Behav 32 1 8
21. RV McDonald LA Parker S Siegel 1997 Conditioned sucrose aversions produced by naloxone-precipitated withdrawal from acutely administered morphine Pharmacol Biochem Behav 58 1003 1008
22. LR McMahon SL Sell CP France 2004 Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys J Pharmacol Exp Ther 308 111 119
23. IO Medvedev OA Dravolina AY Bespalov 1998 Effect of N-methyl-d-aspartate receptor antagonists on discriminative stimulus effects of naloxone in morphine-dependent rats using the Y-maze drug discrimination paradigm J Pharmacol Exp Ther 286 1260 1268
24. CC Michaels SG Holtzman 2007 Enhanced sensitivity to naltrexone-induced drinking suppression of fluid intake and sucrose consumption in maternally separated rats Pharmacol Biochem Behav 86 784 796
25. S Miksic G Sherman H Lal 1981 Discriminative response control by naloxone in morphine pretreated rats Psychopharmacology (Berl) 72 179 184
26. R Mucha A Herz 1985 Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning Psychopharmacology (Berl) 86 274 280
27. RF Mucha MJ Walker 1987 Aversive property of opioid receptor blockade in drug-naïve mice Psychopharmacology (Berl) 93 483 488
28. RF Mucha MJ Millan A Herz 1985 Aversive properties of naloxone in non-dependent (naïve) rats may involve blockade of central β-endorphin Psychopharmacology (Berl) 86 281 285
29. National Research Council (1996) Guide for the care and use of laboratory animals. National Academy, Washington DC
30. National Research Council (2003) Guidelines for the care and use of mammals in neuroscience and behavioral research. National Academy, Washington DC
31. SS Negus 2006 Choice between heroin and food in nondependent and heroin-dependent rhesus monkeys: effects of naloxone, buprenorphine, and methadone J Pharmacol Exp Ther 317 711 723
32. DA Overton SK Batta 1979 Investigation of narcotics and antitussives using drug discrimination techniques J Pharmacol Exp Ther 211 401 408
33. LA Parker M Rennie 1992 Naltrexone-induced aversions: assessment by place conditioning, taste reactivity, and taste avoidance paradigms Pharmacol Biochem Behav 41 559 565
34. LA Parker JA Cyr AN Santi PD Burton 2002 the aversive properties of acute morphine dependence persist 48 h after a single exposure to morphine: evaluation by taste and place conditioning Pharmacol Biochem Behav 72 87 92
35. S Pournagash AL Riley 1993 Buprenorphine as a stimulus in drug discrimination learning: an assessment of mu and kappa receptor activity Pharmacol Biochem Behav 46 593 604
36. S Pournagash AL Riley 1995 The effects of chronic morphine on the generalization of buprenorphine stimulus control: an assessment of kappa antagonist activity Pharmacol Biochem Behav 52 779 787
37. Riley AL (1997) Drug discrimination learning: assessment of opioid receptor pharmacology. In: Bouton ME, Fanselow MS (eds) Learning, motivation, and cognition: the functional behaviorism of Robert C. Bolles. American Psychological Association, Washington, DC, pp 225-254
38. SL Sell LR McMahon CP France 2003 Relative efficacy of buprenorphine, napbuphine and morphine in opioid-treated rhesus monkeys discriminative naltrexone J Pharmacol Exp Ther 306 1167 1173
39. HE Shannon EJ Cone CW Gorodetzky 1984 Morphine-like discriminative stimulus effects buprenorphine and demethoxybuprenorphine in rats: quantitative antagonism by naloxone J Pharmacol Exp Ther 229 768 774
40. PD Skoubis HW Matthes WM Walwyn BL Kieffer NT Maidment 2001 Naloxone fails to produce conditioned place aversion in m-opioid receptor knock-out mice Neuroscience 106 757 763
41. ST Smurthwaite MA Kautz B Geter AL Riley 1992 Naloxone as a stimulus in drug discrimination learning: generalizations to other opiate antagonists Pharmacol Biochem Behav 41 1 43 47
42. GW Stevenson S Pournaghash AL Riley 1991 Antagonism of drug discrimination learning within the conditioned taste aversion procedure Pharmacol Biochem Behav 41 245 249
43. Stolerman IP, D'Mello G (1981) Oral self-administration and the relevance of conditioned taste aversions. In: Thompson T, Dews PB, McKim WA (eds) Advances in behavioral pharmacology, vol 3. Academic, New York, pp 169-214
44. IP Stolerman CW Pilcher G D'Mello 1978 Aversive properties of narcotic antagonists in rats Neuropharmacology 17 427
45. RJ Valentino S Herling JH Woods 1983 Discriminative stimulus effects of naltrexone in narcotic-naïve and morphine-treated pigeons J Pharmacol Exp Ther 224 307 313
46. Weissman A (1978) The discriminability of naloxone in rats depends on concomitant morphine treatment. In: Colpaert FC, Rosecrans JA (eds) Stimulus properties of drugs: ten years of progress. Elsevier, Amsterdam, pp 209-214
47. DA White ML Hwang SG Holtzman 2005 Naltrexone-induced conditioned place aversion following a single dose of morphine in the rat Pharmacol Biochem Behav 81 451 458