Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound

Journal of Pharmacology and Experimental Therapeutics

Volumn 328, Issue 3, 2009, Pages 866-872

  Hu, Wenxian ^a   Hofstetter, Wayne ^b   Wei, Xiaoli ^b   Guo, Wei ^b   Zhou, Yanbin ^b   Pataer, Abujiang ^b   Li, Hong ^a   Fang, Bingliang ^b   Swisher, Stephen G ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 2 IMINO A (PHENOXYMETHYL) 3 (PHENYLMETHYL) 1H BENZIMIDAZOLE 1 ETHANOL; ADENOVIRUS VECTOR; BENZIMIDAZOLE DERIVATIVE; CASPASE 3; INITIATION FACTOR 2ALPHA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE R; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SENSITIVITY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VACCINIA VIRUS; VIRUS REPLICATION;

ANIMALS; APOPTOSIS; BENZIMIDAZOLES; CELL LINE, TUMOR; CELL SURVIVAL; EIF-2 KINASE; HELA CELLS; HUMANS; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; RNA, DOUBLE-STRANDED; VACCINIA VIRUS; VIRUS REPLICATION;

EID: 62449159500     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.141754     Document Type: Article

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