Atrial Na,K-ATpase increase and potassium dysregulation accentuate the risk of postoperative atrial fibrillation

Cardiology

Volumn 114, Issue 1, 2009, Pages 1-7

  Tran, Cao Thach ^a,b   Schmidt, Thomas Andersen ^c   Christensen, John Brochorst ^c   Kjeldsen, Keld ^a,b  

^a University of Copenhagen   (Denmark)

^b DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Arrhythmias; Atrial fibrillation; Cardiac surgery; Diuretics; Na,K ATPase; Potassium; Prediction

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); POTASSIUM;

AGED; ARTICLE; CARDIOVASCULAR RISK; FEMALE; HEART ATRIUM; HEART ATRIUM FIBRILLATION; HEART MUSCLE BIOPSY; HEART SURGERY; HOMEOSTASIS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; SINUS RHYTHM;

AGED; ATRIAL FIBRILLATION; DENMARK; FEMALE; HEART ATRIA; HOMEOSTASIS; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIUM; OUABAIN; POSTOPERATIVE COMPLICATIONS; POTASSIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; THORACIC SURGERY;

EID: 62449106024     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000209264     Document Type: Article

References (34)

1. Mayson SE, Greenspon AJ, Adams S, et al: The changing face of postoperative atrial fibrillation prevention: a review of current medical therapy. Cardiol Rev 2007;15:231-241.
2. Walsh SR, Oates JE, Anderson JA, Blair SD, Makin CA, Walsh CJ: Postoperative arrhythmias in colorectal surgical patients: incidence and clinical correlates. Colorectal Dis 2006;8:212-216.
3. Kim MH, Deeb GM, Morady F, et al: Effect of postoperative atrial fibrillation on length of stay after cardiac surgery [the Postoperative Atrial Fibrillation in Cardiac Surgery Study (PACS2)]. Am J Cardiol 2001;87:881-885.
4. Villareal R P, Hariharan R, Liu BC, et al: Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. J Am Coll Cardiol 2004;43:742-748.
5. Macdonald JE, Struthers AD: What is the optimal serum potassium level in cardiovascular patients? J Am Coll Cardiol 2004;43:155-161.
6. Wahr JA, Parks R, Boisvert D, et al: Preoperative serum potassium levels and perioperative outcomes in cardiac surgery patients. Multicenter Study of Perioperative Ischemia Research Group. JAMA 1999;281:2203-2210.
7. Kalman JM, Munawar M, Howes LG, et al: Atrial fibrillation after coronary artery bypass grafting is associated with sympathetic activation. Ann Thorac Surg 1995;60:1709-1715.
8. + pump. Clin Sci (Lond) 1998;95:3-17.
9. Sejersted OM, Sjøgaard G: Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise. Physiol Rev 2000;80:1411-1481.
10. Crystal E, Connolly SJ, Sleik K, Ginger TJ, Yusuf S: Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis. Circulation 2002;106:75-80.
11. + pump current undergo remodeling in atrial fibrillation? Cardiovasc Res 2003;59:536-537.
12. Glitsch HG: Electrophysiology of the sodi-um-potassium-ATPase in cardiac cells. Physiol Rev 2001;81:1791-1826.
13. + channels. Circ Res 1998;82:739-750.
14. Choy AM, Lang CC, Chomsky DM, Rayos GH, Wilson JR, Roden DM: Normalization of acquired QT prolongation in humans by intravenous potassium. Circulation 1997;96: 2149-2154.
15. Etheridge SP, Compton SJ, Tristani-Firouzi M, Mason JW: A new oral therapy for long QT syndrome: long-term oral potassium improves repolarization in patients with HERG mutations. J Am Coll Cardiol 2003;42:1777-1782.
16. Nørgaard A, Bagger JP, Bjerregaard P, Baandrup U, Kjeldsen K, Thomsen PE: Relation of left ventricular function and Na,K-pump concentration in suspected idiopathic dilated cardiomyopathy. Am J Cardiol 1988;61: 1312-1315.
17. Schwinger RH, Bundgaard H, Müller-Ehm-sen J, Kjeldsen K: The Na,K-ATPase in the failing human heart. Cardiovasc Res 2003;57:913-920.
18. Schmidt TA, Allen PD, Colucci WS, Marsh JD, Kjeldsen K: No adaptation to digitalization as evaluated by digitalis receptor (Na,KATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure. Am J Cardiol 1993;71:110-114.
19. 3Houabain binding to intact myocardial samples. Stability to short term ischemia reper-fusion. Basic Res Cardiol 1990;85:411-427.
20. Wang GX, Schmied R, Ebner F, Korth M: Intracellular sodium activity and its regulation in guinea-pig atrial myocardium. J Physiol 1993;465:73-84.
21. ++ exchanger in the human heart. J Clin Invest 1996;98:1650-1658.
22. 2+ currents and human atrial fibrillation. Circ Res 1999;85:428-436.
23. Dupont E, Ko Y, Rothery S, et al: The gapjunctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillation. Circulation 2001;103:842-849.
24. Maixent JM, Duran MJ, Pierre S, et al: Remodeling of Na,K-ATPase, and membrane fluidity after atrial fibrillation in sheep. J Re-cept Signal Transduct Res 2002;22:201-211.
25. Workman AJ, Kane KA, Rankin AC: Characterisation of the Na, K pump current in atrial cells from patients with and without chronic atrial fibrillation. Cardiovasc Res 2003;59:593-602.
26. + depletion and changes in thyroid status. Eur J Pharmacol 1985;113:373-382.
27. Bundgaard H: Potassium depletion improves myocardial potassium uptake in vivo. Am J Physiol Cell Physiol 2004;287:C135-C141.
28. Dørup I, Sk aja a K, Clau sen T, Kjeldsen K: Reduced concentrations of potassium, magnesium, and sodium-potassium pumps in human skeletal muscle during treatment with diuretics. Br Med J (Clin Res Ed) 1988;296: 455-458.
29. Müller-Ehmsen J, Wang J, Schwinger RH, McDonough AA: Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart - right atrium versus left ventricle. Cell Mol Biol (Noisy-le-grand) 2001;47:373-381.
30. +-ATPase in hearts. Am J Physiol Heart Circ Physiol 2003;285:H1055-H1063.
31. + regulation in cardiac myocytes. Cardiovasc Res 2003;57:897-912.
32. Tieleman RG, De Langen C, Van Gelder IC, et al: Verapamil reduces tachycardia-induced electrical remodeling of the atria. Circulation 1997;95:1945-1953.
33. Bosch RF, Nattel S: Cellular electrophysiology of atrial fibrillation. Cardiovasc Res 2002;54:259-269.
34. Bakhtiary F, Therapidis P, Dzemali O, et al: Impact of high thoracic epidural anesthesia on incidence of perioperative atrial fibrillation in off-pump coronary bypass grafting: a prospective randomized study. J Thorac Cardiovasc Surg 2007;134:460-464.