Multi-photon excitation fluorescence microscopy of brain-tumour tissue and analysis of cell density

Acta Neurochirurgica

Volumn 151, Issue 3, 2009, Pages 253-262

  Kantelhardt, Sven Rainer ^a   Leppert, Jan ^b   Kantelhardt, Jan Werner ^c   Reusche, Erich ^b   Hüttmann, Gereon ^d   Giese, Alf ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^d UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Cell density; Extent of resection; Fluorescence microscopy; Glioma; Multi photon excitation; Tumour invasion

Indexed keywords

EOSIN; HEMATOXYLIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN BIOPSY; BRAIN TUMOR; CELL DENSITY; CELL NUCLEUS; DIAGNOSTIC IMAGING; GLIOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; INTERMETHOD COMPARISON; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; STAINING; THREE DIMENSIONAL IMAGING; TISSUE SECTION; TUMOR BIOPSY; TUMOR CELL; TUMOR DIFFERENTIATION;

ANIMALS; BIOPSY; BRAIN; BRAIN NEOPLASMS; CELL COUNT; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GLIOMA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; NEOPLASM INVASIVENESS; PREDICTIVE VALUE OF TESTS;

EID: 62149124033     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-009-0188-6     Document Type: Article

References (32)

1. A Bogaards A Varma SP Collens A Lin A Giles VX Yang JM Bilbao LD Lilge PJ Muller BC Wilson 2004 Increased brain tumour resection using fluorescence image guidance in a preclinical model Lasers Surg Med 35 3 181 190
2. HJ Böhringer D Boller J Leppert U Knopp E Lankenau E Reusche G Hüttmann A Giese 2006 Time-domain and spectral-domain optical coherence tomography in the analysis of brain tumour tissue Lasers Surg Med 38 6 588 597
3. HJ Böhringer E Lankenau V Rohde G Hüttmann A Giese 2006 Optical coherence tomography for experimental neuroendoscopy Minim Invasive Neurosurg 49 5 269 275
4. G Bottiroli AC Croce D Locatelli R Nano E Giombelli A Messina E Benericetti 1998 Brain tissue autofluorescence: an aid for intra-operative delineation of tumour resection margins Cancer Detect Prev 22 330 339
5. A Giese T Kucinski U Knopp R Goldbrunner W Hamel HM Mehdorn JC Tonn D Hilt M Westphal 2004 Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma J Neurooncol 66 3 351 360
6. A Giese R Bjerkvig ME Berens M Westphal 2003 Cost of migration: invasion of malignant gliomas and implications for treatment J Clin Oncol 21 8 1624 1636
7. SR Kantelhardt H Diddens J Leppert N Pettkus V Rohde G Hüttmann A Giese 2008 Multi-photon excitation fluorescence microscopy of 5-aminolevulinic acid induced fluorescence in experimental gliomas Laser Surg Med 40 273 281
8. SR Kantelhardt J Leppert J Krajewski N Petkus E Reusche VM Tronnier G Huttmann A Giese 2007 Imaging of brain and brain tumour specimens by time-resolved multi-photon excitation microscopy ex vivo Neuro-oncol 2 103 112
9. GE Keles KR Lamborn MS Berger 2001 Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcome J Neurosurg 95 735 745
10. D Kim KH Kim S Yazdanfar PTC So 2004 High-speed handheld multi-photon multifoci microscopy. Multi-photon microscopy in the biomedical science IV, at Biomedical Optics 2001, San Jose, CA SPIE Proc 5323 267 272
11. KH Kim C Buehler PTC So 1999 High-speed, two-photon scanning microscope Appl Opt 38 6004 6009
12. K König A Ehlers I Riemann S Schenkl R Buckle M Kaatz 2007 Clinical two-photon microendoscopy Microsc Res Tech 70 398 402
13. K König K Schenke-Layland I Riemann UA Stock 2005 Multi-photon autofluorescence imaging of intratissue elastic fibres Biomaterials 26 495 500
14. K König I Rieman 2003 High-resolution multi-photon tomography of human skin with subcellular spatial resolution and picosecond time resolution J Biomed Optics 8 432 439
15. K König 2000 Multi-photon microscopy in life science J Microsc 200 83 104
16. M Lacroix D Abi-Said DR Fourney ZL Gokaslan W Shi F DeMonte FF Lang IE McCutcheon SJ Hassenbusch E Holland K Hess C Michael D Miller R Sawaya 2001 A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival J Neurosurg 95 190 198
17. E Lankenau D Klinger C Winter A Malik HH Müller S Oelckers HW Pau T Just G Hüttmann 2007
18. WC Lee H Huang G Feng JR Sanes EN Brown PT So E Nedivi 2006 Dynamic remodeling of dendritic arbors in GABAergic interneurons of adult visual cortex PLoS Biol 4 2 e29
19. J Leppert J Krajewski SR Kantelhardt S Schlaffer N Petkus E Reusche G Huttmann A Giese 2006 Multi-photon excitation of autofluorescence for microscopy of glioma tissue Neurosurgery 58 4 759 767
20. WC Lin SA Toms M Motamedi ED Jansen A Mahadevan-Jansen 2000 Brain tumour demarcation using optical spectroscopy; an in vitro study J Biomed Opt 5 214 220
21. SK Majumder S Gebhart MD Johnson R Thompson WC Lin A Mahadevan-Jansen 2007 A probability-based spectroscopic diagnostic algorithm for simultaneous discrimination of brain tumour and tumour margins from normal brain tissue Appl Spectrosc 61 548 557
22. BR Masters PT So E Gratton 1998 Multi-photon excitation microscopy of in vivo human skin. Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy Ann N Y Acad Sci 838 58 67
23. BR Masters PT So E Gratton 1997 Multi-photon excitation fluorescence microscopy and spectroscopy of in vivo human skin Biophys J 72 2405 2412
24. HW Pau E Lankenau T Just D Behrend G Hüttmann 2007 Optical coherence tomography as an orientation guide in cochlear implant surgery? Acta Otolaryngol 127 9 907 913
25. Rezk-Salama C, Engel K, Bauer M, Greiner G, Ertl T (2000) Interactive Volume Rendering on Standard PC Graphics Hardware Using Multi-Textures and Multi-Stage Rasterisation; in Proc. Eurographics SIGGRAPH Workshop on Graphics Hardware 2000
26. W Stummer U Pichlmeier T Meinel OD Wiestler F Zanella HJ Reulen ALA-Glioma Study Group 2006 Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial Lancet Oncol 7 5 392 401
27. W Stummer A Novotny H Stepp C Goetz K Bise HJ Reulen 2000 Fluorescence-guided resection of glioblastoma multiforme by using 5-aminolevulinic acid-induced porphyrins: a prospective study in 52 consecutive patients J Neurosurg 93 6 1003 1013
28. W Stummer H Stepp G Möller A Ehrhardt M Leonhard HJ Reulen 1998 Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue Acta Neurochir (Wien) 140 10 995 1000
29. R Stupp WP Mason MJ van den Bent M Weller B Fisher MJ Taphoorn K Belanger AA Brandes C Marosi U Bogdahn J Curschmann RC Janzer SK Ludwin T Gorlia A Allgeier D Lacombe JG Cairncross E Eisenhauer RO Mirimanoff European Organisation for Research and Treatment of Cancer Brain Tumour and Radiotherapy Groups National Cancer Institute of Canada Clinical Trials Group 2005 Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 10 987 996
30. K Teuchner W Freyer D Leupold A Volkmer DJ Birch P Altmeyer M Stucker K Hoffmann 1999 Femtosecond two-photon excited fluorescence of melanin Photochem Photobiol 70 146 151
31. S Utsuki H Oka S Sato S Shimizu S Suzuki Y Tanizaki K Kondo Y Miyajima K Fujii 2007 Histological examination of false positive tissue resection using 5-aminolevulinic acid-induced fluorescence guidance Neurol Med Chir (Tokyo) 47 5 210 213
32. M Westphal Z Ram V Riddle D Hilt E Bortey Executive Committee of the Gliadel Study Group 2006 Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial Acta Neurochir (Wien) 148 3 269 275