Titration and implementation of neurally adjusted ventilatory assist in critically III patients

Chest

Volumn 135, Issue 3, 2009, Pages 695-703

  Brander, Lukas ^a   Howard, Leong Poi ^b   Beck, Jennifer ^b   Brunet, Fabrice ^b   Hutchison, Stuart J ^b   Slutsky, Arthur S ^b   Sinderby, Christer ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Diaphragm; Electromyography; Respiration; Respiratory failure; Ventilators

Indexed keywords

ADULT; AGED; AIRWAY PRESSURE; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; ARTICLE; ASSISTED VENTILATION; CARDIOPULMONARY FUNCTION; CLINICAL ARTICLE; CRITICALLY ILL PATIENT; DIAPHRAGM; ELECTRIC ACTIVITY; ESOPHAGUS PRESSURE; FEMALE; HUMAN; MALE; NEURALLY ADJUSTED VENTILATORY ASSIST; PRIORITY JOURNAL; RESPIRATORY DRIVE; TIDAL VOLUME;

EID: 62149108945     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.08-1747     Document Type: Article

References (29)

1. Sinderby C, Navalesi P, Beck J, et al. Neural control of mechanical ventilation in respiratory failure. Nat Med 1999; 5:1433-1436
2. Allo JC, Beck J, Brander L, et al. Influence of neurally adjusted ventilatory assist (NAVA) and PEEP on breathing pattern in rabbits with acute lung injury. Crit Care Med 2006; 34:2997-3004
3. Sinderby C, Beck J, Spahija J, et al. Inspiratory muscle unloading by neurally adjusted ventilatory assist during maximal inspiratory efforts in healthy subjects. Chest 2007; 131:711-717
4. Beck J, Campoccia F, Alio JC, et al. Improved synchrony and respiratory unloading by neurally adjusted ventilatory assist (NAVA) in lung-injured rabbits. Pediatr Res 2007; 61:289-294
5. Sinderby CA, Beck JC, Lindstrom LH, et al. Enhancement of signal quality in esophageal recordings of diaphragm EMG. J Appl Physiol 1997; 82:1370-1377
6. Sinderby C, Spahija J, Beck J. Changes in respiratory effort sensation over time are linked to the frequency content of diaphragm electrical activity. Am J Respir Crit Care Med 2001; 163:905-910
7. Sinderby C, Beck J, Spahija J, et al. Voluntary activation of the human diaphragm in health and disease. J Appl Physiol 1998; 85:2146-2158
8. Sinderby C, Spahija J, Beck J, et al. Diaphragm activation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 163:1637-1641
9. Spahija J, Beck J, de Marchie M, et al. Closed-loop control of respiratory drive using pressure-support ventilation: target drive ventilation. Am J Respir Crit Care Med 2005; 171:1009-1014
10. Alio JC, Beck JC, Brander L, et al. Influence of neurally adjusted ventilatory assist and positive end-expiratory pressure on breathing pattern in rabbits with acute lung injury. Crit Care Med 2006; 34:2997-3004
11. Marantz S, Patrick W, Webster K, et al. Response of ventilator-dependent patients to different levels of proportional assist. J Appl Physiol 1996; 80:397-403
12. Kondili E, Xirouchaki N, Vaporidi K, et al. Short-term cardiorespiratory effects of proportional assist and pressure-support ventilation in patients with acute lung injury/acute respiratory distress syndrome. Anesthesiology 2006; 105:703-708
13. Colombo D, Cammarota G, Bergamasehi V, et al. Physiologic response to varying levels of pressure support and neurally adjusted ventilatory assist in patients with acute respiratory failure. Intensive Care Med 2008; 34:2010-2018
14. Leung P, Jubran A, Tobin MJ. Comparison of assisted ventilator modes on triggering, patient effort, and dyspnea. Am J Respir Crit Care Med 1997; 155:1940-1948
15. Younes M, Kun J, Webster K, et al. Response of ventilator-dependent patients to delayed opening of exhalation valve. Am J Respir Crit Care Med 2002; 166:21-30
16. Giannouli E, Webster K, Roberts D, et al. Response of ventilator-dependent patients to different levels of pressure support and proportional assist. Am J Respir Crit Care Med 1999; 159:1716-1725
17. Supinski GS, Dick T, Stofan D, et al. Effects of intraphrenic injection of potassium on diaphragm activation. J Appl Physiol 1993; 74:1186-1194
18. Ma A, Bravo M, Kappagoda CT. Responses of bronchial C-fiber afferents of the rabbit to changes in lung compliance. Respir Physiol Neurobiol 2003; 138:155-163
19. Schulze A, Rich W, Schellenberg L, et al. Effects of different gain settings during assisted mechanical ventilation using respiratory unloading in rabbits. Pediatr Res 1998; 44:132-138
20. Viale JP, Duperret S, Mahul P, et al. Time course evolution of ventilatory responses to inspiratory unloading in patients. Am J Respir Crit Care Med 1998; 157:428-434
21. Emeriaud G, Beck J, Tucci M, et al. Diaphragm electrical activity during expiration in mechanically ventilated infants. Pediatr Res 2006; 59:705-710
22. Jubran A, Grant BJ, Laghi F, et al. Weaning prediction: esophageal pressure monitoring complements readiness testing. Am J Respir Crit Care Med 2005; 171:1252-1259
23. Yang KL, Tobin MJ. A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation. N Engl J Med 1991; 324:1445-1450
24. Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
25. Imai Y, Parodo J, Kajikawa O, et al. Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 2003; 289:2104-2112
26. Parsons PE, Eisner MD, Thompson BT, et al. Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 2005; 33:1-6
27. Ranieri VM, Suter PM, Tortorella C, et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 1999; 282:54-61
28. Wrigge H, Golisch W, Zinserling J, et al. Proportional assist versus pressure support ventilation: effects on breathing pattern and respiratory work of patients with chronic obstructive pulmonary disease. Intensive Care Med 1999; 25:790-798
29. Delaere S, Roeseler J, D'hoore W, et al. Respiratory muscle workload in intubated, spontaneously breathing patients without COPD: pressure support vs proportional assist ventilation. Intensive Care Med 2003; 29:949-954