메뉴 건너뛰기




Volumn 6, Issue 1, 2009, Pages 77-78

The perils of Alzheimer's drug development

Author keywords

[No Author keywords available]

Indexed keywords

BAPINEUZUMAB; DONEPEZIL; METRIFONATE; PHENSERINE; PLACEBO; TACRINE;

EID: 62149097584     PISSN: 15672050     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720509787313871     Document Type: Note
Times cited : (27)

References (9)
  • 1
    • 48749125741 scopus 로고    scopus 로고
    • Alzheimer's Disease Drug Development in 2008 and beyond: Problems and Opportunities
    • Becker RE and Greig NH. Alzheimer's Disease Drug Development in 2008 and beyond: Problems and Opportunities. Curr Alzheimer Res 5(4): 346-57 (2008).
    • (2008) Curr Alzheimer Res , vol.5 , Issue.4 , pp. 346-357
    • Becker, R.E.1    Greig, N.H.2
  • 2
    • 38049022527 scopus 로고    scopus 로고
    • Prevention therapeutics of dementia
    • Schneider LS. Prevention therapeutics of dementia. Alzheimer Demen 4(1): S122-S130 (2008).
    • (2008) Alzheimer Demen , vol.4 , Issue.1
    • Schneider, L.S.1
  • 4
    • 84884840827 scopus 로고    scopus 로고
    • Issues in design and conductance of clinical trials for cognitive-enhancing drugs
    • McArthur RA and Borsini F, Eds, Elsevier, New York, in press
    • Schneider LS. Issues in design and conductance of clinical trials for cognitive-enhancing drugs. In: McArthur RA and Borsini F, Eds. Animal and Translational Models of Behavioural Disorders, Neurological Disorders. Elsevier, New York 2 (2008) (in press).
    • (2008) Animal and Translational Models of Behavioural Disorders, Neurological Disorders , pp. 2
    • Schneider, L.S.1
  • 5
    • 41149127264 scopus 로고    scopus 로고
    • Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease
    • Kadir A, Andreasen N, Almkvist O, Wall A, Forsberg A, Engler H, et al. Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease. Ann Neurol 63(5): 621-31 (2008).
    • (2008) Ann Neurol , vol.63 , Issue.5 , pp. 621-631
    • Kadir, A.1    Andreasen, N.2    Almkvist, O.3    Wall, A.4    Forsberg, A.5    Engler, H.6
  • 6
    • 0036279726 scopus 로고    scopus 로고
    • Barriers to Alzheimer's disease drug discovery and development in the biotechnology industry
    • Altstiel LD. Barriers to Alzheimer's disease drug discovery and development in the biotechnology industry. Alzheimer Dis Assoc Disord (Supp 1): S29-S32 (2002).
    • (2002) Alzheimer Dis Assoc Disord , Issue.SUPP 1
    • Altstiel, L.D.1
  • 7
    • 0007691164 scopus 로고
    • Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease
    • Poirier J, Delisle M, Quirion R, Aubert I, Farlow M, Lahiri DK, et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease. Proc Natl Acad Sci USA 92: 12260-12264 (1995).
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12260-12264
    • Poirier, J.1    Delisle, M.2    Quirion, R.3    Aubert, I.4    Farlow, M.5    Lahiri, D.K.6
  • 8
    • 0031943549 scopus 로고    scopus 로고
    • Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease
    • Farlow MR, Lahiri DK, Poirier J, Davignon J, Schneider L and Hui SL. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Neurology 50(3): 669-77 (1998).
    • (1998) Neurology , vol.50 , Issue.3 , pp. 669-677
    • Farlow, M.R.1    Lahiri, D.K.2    Poirier, J.3    Davignon, J.4    Schneider, L.5    Hui, S.L.6
  • 9
    • 33745266146 scopus 로고    scopus 로고
    • Rosiglitazone in Alzheimer's Disease Study Group. Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
    • Risner ME, Saunders AM, Altman JF, Ormandy GC, Craft S, Foley IM, et al. Rosiglitazone in Alzheimer's Disease Study Group. Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J 6(4): 246-54 (2006).
    • (2006) Pharmacogenomics J , vol.6 , Issue.4 , pp. 246-254
    • Risner, M.E.1    Saunders, A.M.2    Altman, J.F.3    Ormandy, G.C.4    Craft, S.5    Foley, I.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.