The relationship between epilepsy and autism: A continuing debate

Acta Paediatrica, International Journal of Paediatrics

Volumn 98, Issue 4, 2009, Pages 618-620

  Besag, Frank M C ^a  

^a Twinwoods Health Resource Centre   (United Kingdom)

Author keywords

Autism; Epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; PSYCHOTROPIC AGENT; VIGABATRIN;

AUTISM; BRAIN FUNCTION; CAUSAL ATTRIBUTION; COMORBIDITY; DETERIORATION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; EEG ABNORMALITY; EPILEPSY; EPILEPTIC DISCHARGE; EPILEPTIC STATE; FEBRILE CONVULSION; GENETIC DISORDER; HUMAN; INFANTILE AUTISM; INFANTILE SPASM; INTELLIGENCE QUOTIENT; LANDAU KLEFFNER SYNDROME; LANGUAGE DISABILITY; MAGNETOENCEPHALOGRAPHY; NOTE; ONSET AGE; PREVALENCE; PRIORITY JOURNAL; SEX RATIO; SLOW WAVE SLEEP; SOCIAL BEHAVIOR; SPEECH ANALYSIS; SPEECH DEVELOPMENT; SPIKE WAVE; TEMPORAL LOBE; TUBEROUS SCLEROSIS;

AGE OF ONSET; AUTISTIC DISORDER; EPILEPSY; HUMANS;

EID: 61849179393     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2008.01190.x     Document Type: Note

References (19)

1. Turk J, Bax M, Williams C, Amin P, Eriksson M, Gillberg C. Autism spectrum disorder in children with and without epilepsy: impact on social functioning and communication. Acta Paediatr 2009 675 81.
2. Dunn DW, Austin JK. Differential diagnosis and treatment of psychiatric disorders in children and adolescents with epilepsy. Epilepsy Behav 2004 5 (Suppl 7 S10 7.
3. Tuchman R, Rapin I. Epilepsy in autism. Lancet Neurol 2002 1 : 352 8.
4. Canitano R. Epilepsy in autism spectrum disorders. Eur Child Adolesc Psychiatry 2007 16 : 61 6.
5. Pavone P, Incorpora G, Fiumara A, Parano E, Trifiletti RR, Ruggieri M. Epilepsy is not a prominent feature of primary autism. Neuropediatrics 2004 35 : 207 10.
6. Mouridsen SE, Rich B, Isager T. Epilepsy and other neurological diseases in the parents of children with infantile autism. A case control study. Child Psychiatry Hum Dev 2008 39 : 1 8.
7. Tuchman RF, Rapin I, Shinnar S. Autistic and dysphasic children. II: epilepsy. Pediatrics 1991 88 : 1219 25.
8. Bolton PF, Park RJ, Higgins JN, Griffiths PD, Pickles A. Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex. Brain 2002 125 : 1247 55.
9. Levisohn PM. The autism-epilepsy connection. Epilepsia 2007 48 (Suppl 5 33 5.
10. Besag FM. The therapeutic dilemma: treating subtle seizures or indulging in electroencephalogram cosmetics? Semin Pediatr Neurol 1995 2 : 261 8.
11. Robinson RO, Baird G, Robinson G, Simonoff E. Landau-Kleffner syndrome: course and correlates with outcome. Dev Med Child Neurol 2001 43 : 243 7.
12. Patry G, Lyagoubi S, Tassinari CA. Subclinical "electrical status epilepticus" induced by sleep in children. A clinical and electroencephalographic study of six cases. Arch Neurol 1971 24 : 242 52.
13. Tassinari CA, Rubboli G. Cognition and paroxysmal EEG activities: from a single spike to electrical status epilepticus during sleep. Epilepsia 2006 47 (Suppl 2 40 3.
14. Besag FM. Behavioral aspects of pediatric epilepsy syndromes. Epilepsy & Behavior 2004 5 (Suppl 1 S3 13.
15. Morrell F, Whisler WW, Smith MC, Hoeppner TJ, De Toledo-Morrell L, et al. Landau-Kleffner syndrome. Treatment with subpial intracortical transection. Brain 1995 118 : 1529 46.
16. Besag F. Relationships between epilepsy, autism and learning disability. Epilepsia 1999 40 : 234.
17. Jambaque I, Chiron C, Dumas C, Mumford J, Dulac O. Mental and behavioural outcome of infantile epilepsy treated by vigabatrin in tuberous sclerosis patients. Epilepsy Res 2000 38 : 151 60.
18. Munoz-Yunta JA, Ortiz T, Palau-Baduell M, Martin-Munoz L, Salvado-Salvado B, Valls-Santasusana A, et al. Magnetoencephalographic pattern of epileptiform activity in children with early-onset autism spectrum disorders. Clin Neurophysiol 2008 119 : 626 34.
19. Hara H. Autism and epilepsy: a retrospective follow-up study. Brain Dev 2007 29 : 486 90.