The synthesis and biological evaluation of some caffeic acid amide derivatives: E-2-Cyano-(3-substituted phenyl)acrylamides

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 7, 2009, Pages 1861-1865

  Zhou, Wei ^a   Li, Hai bo ^b   Xia, Chun nian ^a   Zheng, Xian ming ^c   Hu, Wei xiao ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

^c Zhejiang Huafang Pharmaceuticals Co Ltd   (China)

Author keywords

Biological activity; Cyanoacetamides; E 2 Cyano (3 substituted phenyl)acrylamides; Synthesis

Indexed keywords

ACETYLCHOLINESTERASE; ACRYLAMIDE DERIVATIVE; CAFFEIC ACID AMIDE DERIVATIVE; CAFFEIC ACID DERIVATIVE; CISPLATIN; ENTACAPONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BEL 7402 CELL; BGC 823 CELL; CANCER INHIBITION; CARCINOMA CELL; CELL STRAIN KB; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HEPATOMA CELL; HUMAN; HUMAN CELL; IC 50; KNOEVENAGEL CONDENSATION; PARKINSON DISEASE; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION;

ACRYLAMIDES; CAFFEIC ACIDS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; HUMANS; INHIBITORY CONCENTRATION 50; NITRILES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 61849179358     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.081     Document Type: Article

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