Interferon-α for treatment of essential thrombocythemia during pregnancy: Case report and review of the literature

Fetal Diagnosis and Therapy

Volumn 25, Issue 1, 2009, Pages 136-140

  Séror, Jérémy ^a   Sentilhes, Loïc ^a,b   Lefebvre Lacoeuille, Céline ^b   Marpeau, Loïc ^a  

^a HÔPITAL CHARLES NICOLLE   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

Acetylsalicylic acid; Essential thrombocythemia; Interferon ; JAK 2 mutation

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA INTERFERON; HEMOGLOBIN; HYDROXYUREA; LOW MOLECULAR WEIGHT HEPARIN; PARACETAMOL;

ADULT; ARTICLE; BONE MARROW BIOPSY; CASE REPORT; CELL COUNT; CESAREAN SECTION; COLOR ULTRASOUND FLOWMETRY; DRUG DOSE INCREASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSTOCIA; EPIDURAL ANESTHESIA; ERYTHROCYTE COUNT; FEMALE; GESTATIONAL AGE; GRANULOCYTE; HEADACHE; HEMATOCRIT; HEMATOMA; HEMOGLOBIN BLOOD LEVEL; HUMAN; LEUKOCYTE COUNT; MEGAKARYOCYTE; PREECLAMPSIA; PREGNANCY COMPLICATION; PREGNANCY DIABETES MELLITUS; PREMATURITY; PRIORITY JOURNAL; SPONTANEOUS ABORTION; THROMBOCYTE COUNT; THROMBOCYTHEMIA; THROMBOCYTOSIS; THROMBOPHLEBITIS; VENOUS THROMBOEMBOLISM;

ADULT; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTERFERON-ALPHA; MATERNAL EXPOSURE; PREGNANCY; RISK ASSESSMENT; THROMBOCYTHEMIA, ESSENTIAL;

EID: 61849159262     PISSN: 10153837     EISSN: None     Source Type: Journal    
DOI: 10.1159/000207555     Document Type: Article

References (25)

1. Vantroyen B, Vantraelen D: Management of essential throbocythemia during pregnancy with aspirin, interferon alpha-2a and no treatment: a comparative analysis of the literature. Acta Haematol 2002; 107: 158-169. (Pubitemid 34455080)
2. Martinelli P, Martinelli V, Agangi A, Maruotti GM, Paladini D, Ciancia R, et al: Interferon alpha treatment for pregnant women affected by essential thrombocythemia: case reports and a review. Am J Obstet Gynecol 2004; 191: 2016-2020. (Pubitemid 39601507)
3. Lazzarino M, Vitale A, Morra E, Gagliardi A, Bernasconi P, Torromeo C, et al: Interferon alpha-2b as treatment for Philadelphia-negative chronic myeloproliferative disorders with excessive thrombocytosis. Br J Haematol 1989; 72: 173-177. (Pubitemid 19151137)
4. Fritz M, Vats K, Goyal RK: Neonatal lupus and IUGR following alpha-interferon therapy during pregnancy. J Perinatol 2005; 25: 552-554. (Pubitemid 41122406)
5. Lengfelder E, Griesshammer M, Hehlmann R: Interferon-alpha in the treatment of essential thrombocythemia. Leuk Lymphoma 1996; 22: 135-142.
6. Ozaslan E, Yilmaz R, Simsek H, Tatar G: Interferon therapy for acute hepatitis C during pregnancy. Ann Pharmacother 2002; 36: 1715-1718. (Pubitemid 35265607)
7. Elliot MA, Tefferi A: Interferon-α therapy in polycythemia vera and essential thrombocythemia. Semin Thromb Hemost 1997; 23: 463-472. (Pubitemid 27501786)
8. Pons JC, Lebon P, Frydman R, Delfraissy JF: Pharmacokinetics of interferon-alpha in pregnant women and fetoplacental passage. Fetal Diagn Ther 1995; 10: 7-10.
9. Barbui T, Barosi G, Grossi A, Gugliotta L, Liberato LN, Marchetti M, et al: Practice guidelines for the therapy of essential thrombocythemia: a statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica 2004; 89: 215-232. (Pubitemid 38796497)
10. Passamonti F, Randi ML, Rumi E, Pungolino E, Elena C, Pietra D, et al: Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the JAK2 V617F mutation. Blood 2007; 110: 485-489.
11. Griesshammer M, Grunewald M, Michiels JJ: Acquired thrombophilia in pregnancy: essential thrombocythemia. Semin Thromb Hemost 2003; 29: 205-212. (Pubitemid 36458200)
12. Iwashita T, Fujitani M, Yamamoto Y, Katsurada T, Yoshida Y: Interferon-alfa treatment of essential thrombocythemia during pregnancy. Intern Med 2006; 45: 1161-1164. (Pubitemid 44773968)
13. Milano V, Gabrielli S, Rizzo N, Vianelli N, Gugliotta L, Orsini LF, et al: Successful treatment of essential thrombocythemia in a pregnancy with recombinant interferon-alpha 2a. J Matern Fetal Med 1996; 5: 74-78. (Pubitemid 126718991)
14. Iki S, Usuki K, Kotaki M, Yamaguchi Y: Successful pregnancy and delivery during alpha-interferon therapy for essential thrombocythemia (in Japanese). Rinsho Ketsueki 1999; 40: 1201-1203.
15. Delage R, Demers C, Cantin G, Roy J: Treatment of essential thrombocythemia during pregnancy with interferon-alpha. Obstet Gynecol 1996; 87: 814-817. (Pubitemid 26127114)
16. Williams JM, Schlesinger PE, Gray AG: Successful treatment of essential thrombocythaemia and recurrent abortion with alphainterferon. Br J Haematol 1994; 88: 647-648.
17. Petit JJ, Callis M, Fernandez de Sevilla A: Normal pregnancy in a patient with essential thrombocythemia treated with interferon alpha-2b. Am J Hematol 1992; 40: 80.
18. Pardini S, Dore F, Murineddu M, Bontigli S, Longinotti M, Grigliotti B, et al: Alpha 2b-interferon therapy and pregnancy: report of a case of essential thrombocythemia. Am J Hematol 1993; 43: 78-79. (Pubitemid 23134596)
19. Diez-Martin JL, Banas MH, Fernandez MN: Childbearing age patients with essential thrombocythemia: should they be placed on interferon? Am J Hematol 1996; 52: 331-332.
20. Pérez-Encinas M, Bello JL, Pérez-Crespo S, De Miguel R, Tome S: Familial myeloproliferative syndrome. Am J Hematol 1994; 46: 225-229.
21. Pulik M, Lionnet F, Genet P, Petitdidier C, Jary L: Platelet counts during pregnancy in essential thrombocythemia treated with recombinant alpha-interferon. Br J Haematol 1996; 93: 495. (Pubitemid 26148756)
22. Shpilberg O, Shimon I, Sofer O, Dolitski M, Ben-Bassat I: Transient normal platelet counts and decreased requirement for interferon during pregnancy in essential thrombocythaemia. Br J Haematol 1996; 92: 491-493. (Pubitemid 26042947)
23. Vianelli N, Gugliotta L, Tura S, Bovicelli L, Rizzo N, Gabrielli A: Interferon-alpha 2a treatment in a pregnant woman with essential thrombocythemia. Blood 1994; 83: 874-875. (Pubitemid 24043754)
24. Thornley S, Manoharan A: Successful treatment of essential thrombocythemia with alpha interferon during pregnancy. Eur J Haematol 1994; 52: 63-64. (Pubitemid 24039766)
25. Koh LP, Devendra K, Tien SL: Four pregnancies in two patients with essential thrombocythaemia: a case report. Ann Acad Med Singapore 2002; 31: 353-356. (Pubitemid 34733730)