Impact of a new national screening policy for Down's syndrome in Denmark: Population based cohort study

BMJ (Online)

Volumn 338, Issue 7692, 2009, Pages 449-452

  Ekelund, Charlotte K ^a   Jørgensen, Finn Stener ^b   Petersen, Olav Bjørn ^c   Sundberg, Karin ^a   Tabor, Ann ^a,d   Andersen, Hans Jakob ^e   Christensen, Jeanette ^e   Ersbak, Vibeke ^e   Farlie, Richard ^e   Henriques, Carsten ^e   Olesen, Annette Wind ^e   Holmskov, Anni ^e   Jensen, Lisa Neerup ^e   Kristiansen, Anette ^e   Larsen, Torben ^e   Poulsen, Hedvig ^e   Ramb, Jan ^e   Skibsted, Lillian ^e   Skovbo, Peter ^e   Sommer, Steffen ^e   Sperling, Lene ^e   Juul, Susanne Vemmelund ^e   Zingenberg, Helle ^e   more..

^a Rigshospitalet   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMNIOCENTESIS; ARTICLE; CHORION VILLUS SAMPLING; CONFIDENCE INTERVAL; CYTOGENETICS; DENMARK; DETERIORATION; DOWN SYNDROME; FEMALE; FIRST TRIMESTER PREGNANCY; HEALTH CARE SYSTEM; HUMAN; MAJOR CLINICAL STUDY; MATERNAL AGE; NEWBORN; OUTCOME ASSESSMENT; POLICY; POPULATION BASED CASE CONTROL STUDY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; REGISTER; RISK ASSESSMENT; SCREENING;

EID: 61849156196     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.a2547     Document Type: Article

References (18)

1. Danish National Board of Health. Report froma working commission "Prenatal diagnosis and risk assessment." www.sst.dk/upload/ fosterdiagnostik1-001.pdf. 2003.
2. Jorgensen FS. [Organization of obstetric ultrasoundinDenmark 2000. Description of the development since 1990]. Ugeskr Laeger 2003;165:4404-9.
3. Morris JK, Mutton DE, Alberman E. Revised estimates of the maternal age specific live birth prevalence of Down's syndrome. J Med Screen 2002;9:2-6.
4. Snijders RJ, Sundberg K, Holzgreve W, Henry G, Nicolaides KH. Maternal age- and gestation-specific risk for trisomy 21. Ultrasound Obstet Gynecol 1999;13:167-70.
5. Torring N, Jolving LR, Petersen OB, Holmskov A, Hertz JM, Uldbjerg N. [Prenatal diagnostics in Arhus and Viborg counties after implementation of first trimester risk assessment]. Ugeskr Laeger 2008;170:50-4.
6. BangsgaardL, Tabor A. OC30: Are pregnant women and their partners making an informed choice about first-trimester risk assessment for Down syndrome? Ultrasound Obstet Gynecol 2007;30:376.
7. Wojdemann KR, Shalmi AC, Christiansen M, Larsen SO, Sundberg K, Brocks V, et al. Improved first-trimester Down syndrome screening performance by lowering the false-positive rate: a prospective study of 9941 low-risk women. Ultrasound Obstet Gynecol 2005;25:227-33.
8. Alfirevic Z, Sundberg K, Brigham S. Amniocentesis and chorionic villus sampling for prenatal diagnosis. Cochrane Database Syst Rev 2003;(3):CD003252.
9. Hadlow NC, Hewitt BG, Dickinson JE, Jacoby P, Bower C. Community-based screening for Down's syndrome in the first trimester using ultrasound and maternal serum biochemistry. Br J Obstet Gynaecol 2005;112:1561-4.
10. O'Leary P, Breheny N, Dickinson JE, Bower C, Goldblatt J, Hewitt B, et al. First-trimester combined screening for Down syndrome and other fetal anomalies. Obstet Gynecol 2006;107:869-76.
11. Soergel P, Pruggmayer M, Schwerdtfeger R, Muhlhaus K, Scharf A. Screening for trisomy 21 with maternal age, fetal nuchal translucency and maternal serum biochemistry at 11-14 weeks: a regional experience from Germany. Fetal Diagn Ther 2006;21:264-8.
12. Spencer K, Spencer CE, Power M, Dawson C, Nicolaides KH. Screening for chromosomal abnormalities in the first trimester using ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years prospective experience. Br J Obstet Gynaecol 2003;110:281-6.
13. Stenhouse EJ, Crossley JA, Aitken DA, Brogan K, Cameron AD, Connor JM. First-trimester combined ultrasound and biochemical screening for Down syndrome in routine clinical practice. Prenat Diagn 2004;24:774-80.
14. Schielen PC, van Leeuwen-Spruijt M, Belmouden I, Elvers LH, Jonker M, Loeber JG. Multi-centre first-trimester screening for Down syndrome in the Netherlands in routine clinical practice. Prenat Diagn 2006;26:711-8.
15. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O. Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 2005;25:221-6.
16. Chang TC. Antenatal screening for Down syndrome in New Zealand: time for a national screening policy? Aust N Z J Obstet Gynaecol 2006;46:92-6.
17. O'Leary P, Breheny N, Reid G, Charles T, Emery J. Regional variations in prenatal screening across Australia: stepping towards a national policy framework. Aust N Z J Obstet Gynaecol 2006;46:427-32.
18. Reddy UM, Mennuti MT. Incorporating first-trimester Down syndrome studies into prenatal screening: executive summary of the National Institute of Child Health and Human Development workshop. Obstet Gynecol 2006;107:167-73.