Evaluation of urokinase plasminogen activator in urine from individuals with Quebec platelet disorder

Blood Coagulation and Fibrinolysis

Volumn 19, Issue 5, 2008, Pages 463-464

  Diamandis, Maria ^a   Veljkovic, D Kika ^a   Derome, Francine ^a   Rivard, Georges E ^a   Hayward, Catherine P M ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; UROKINASE;

AUTOSOMAL DOMINANT DISORDER; BLEEDING DISORDER; CASE REPORT; CREATININE URINE LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMURIA; GENE MUTATION; HEMATURIA; HEMOSTASIS; HUMAN; LETTER; MEGAKARYOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; QUEBEC PLATELET DISORDER; THROMBOCYTE; UPREGULATION; URINALYSIS;

BLOOD PLATELET DISORDERS; FEMALE; GENETIC DISEASES, INBORN; HUMANS; MALE; QUEBEC; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 61849156179     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328304e099     Document Type: Letter

References (6)

1. Diamandis M, Veljkovic DK, Maurer-Spurej E,Rivard GE, Hayward CPM. The Quebec Platelet Disorder: Features, Pathogenesis and Treatment. Blood Coagul Fibrinolysis 2008; 19:109-119.
2. McKay H, Derome F, Haq MA, Whittaker S, Arnold E, Adam F, et al. Bleeding risks associated with inheritance of the Quebec platelet disorder. Blood 2004; 104:159-165.
3. Husain SS, Gurewich V, Lipinski B. Purification and partial characterization of a single-chain high-molecular-weight form of urokinase from human urine. Arch Biochem Biophys 1983; 220:31-38.
4. Kahr WH, Zheng S, Sheth PM, Pai M, Cowie A, Bouchard M, et al. Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinase-type plasminogen activator. Blood 2001; 98:257-265.
5. Sheth PM, Kahr WH, Haq MA, Veljkovic DK, Rivard GE, Hayward CP. Intracellular activation of the fibrinolytic cascade in the Quebec platelet disorder. Thromb Haemost 2003; 90:293-298.
6. Diamandis M, Adam F, Kahr WH, Wang P, Chorneyko KA, Arsenault AL, et al. Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis. J Thromb Haemost 2006; 4:1086-1094.