Rituximab-based immunosuppression for autoimmune haemolytic anaemia in infants

British Journal of Haematology

Volumn 145, Issue 1, 2009, Pages 96-100

  Svahn, Johanna ^a   Fioredda, Francesca ^a   Calvillo, Michaela ^a   Molinari, Angelo C ^a   Micalizzi, Concetta ^a   Banov, Laura ^a   Schmidt, Madalina ^a,b   Caprino, Daniela ^a   Marinelli, Doretta ^c   Gallisai, Domenico ^d   Dufour, Carlo ^a  

^a G GASLINI INSTITUTE   (Italy)

^b 'Sf Maria' Children Emergency Hospital   (Romania)

^c Perugia Medical Hospital   (Italy)

^d UNIVERSITY OF SASSARI   (Italy)

Author keywords

Autoimmune haemolytic anaemia; Cyclosporine A; Infants; Rituximab

Indexed keywords

CORTICOSTEROID; COTRIMAZINE; COTRIMOXAZOLE; CYCLOSPORIN A; HEMOGLOBIN; IMMUNOGLOBULIN; PREDNISOLONE; RITUXIMAB;

ANTIBIOTIC PROPHYLAXIS; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; B LYMPHOCYTE; CASE REPORT; CATHETER INFECTION; CORTICOSTEROID THERAPY; DRUG DOSE REDUCTION; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; DRUG WITHDRAWAL; ERYTHROCYTE TRANSFUSION; FEMALE; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HEMOLYSIS; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; INFANT; KLEBSIELLA INFECTION; LYMPHOPROLIFERATIVE DISEASE; MAINTENANCE THERAPY; MALE; NEUTROPENIA; PNEUMOCYSTIS PNEUMONIA; PNEUMONIA; PRIORITY JOURNAL; RELAPSE; RETICULOCYTE COUNT; THROMBOCYTOPENIA; TREATMENT FAILURE; TREATMENT RESPONSE;

EID: 61849133952     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07594.x     Document Type: Article

References (15)

1. Castigli, E. Geha, R.S. (2006) Molecular basis of common variable immunodeficiency. Journal of Allergy and Clinical Immunology, 117, 740 746.
2. FDA/Center for Drug Evaluation and Research (2006) FDA public health advisory: life-threatening brain infection in patients with systemic lupus erythematosus after Rituxan (rituximab) treatment. Accessed at: http://www.fda.gov/cder/drug/advisory/rituximab.htm.
3. Giulino, L.B., Bussel, J.B. Neufeld, E.J. and the Pediatric and Platelet Immunology Committees of the TMH Clinical Trial Network (2007) Treatment with rituximab in benign and malignant hematologic disorders in children. Journal of Pediatrics, 150, 338 344.
4. Gottardo, N.G., Baker, D.L. Willis, F.R. (2003) Successful induction and maintenance of long-term remission in a child with chronic relapsing autoimmune hemolytic anemia using rituximab. Pediatric Hematology and Oncology, 20, 557 561.
5. Klink, D.T., van Elburg, R.M., Schreurs, W.J. van Well, G.T.J. (2008) Rituximab administration in third trimester of pregnancy suppresses neonatal B-cell develpoment. Clinical & Developmental Immunology, 2008, 271363.
6. Larrar, S., Guitton, C., Willems, M. Bader-Meunier, B. (2006) Severe hematological side effects following Rituximab therapy in children. Haematol, 91, 8 (suppl ECR36.
7. Motta, M., Cavazza, A., Migliori, C. Chirico, G. (2003) Autoimmune haemolytic anaemia in a newborn infant. Archives of Disease in Childhood. Fetal and Neonatal Edition, 88, F341 F342.
8. Nathan, D.G., Orkin, S.H., Ginsburg, D. Look, A.T. (2003) Appendix 27, Nathan and Oski's Hematology of Infancy and Childhood. WB Saunders, Philadelphia, PA, USA.
9. Ng, P.C., Lee, K.K.M., Lo, A.F.C., Li, C.K. Fok, T.F. (2003) Anti B cell targeted immunotherapy for treatment of refractory autoimmune haemolytic anaemia in a young infant. Archives of Disease in Childhood, 88, 337 339.
10. Nowak-Wegrzyn, A., King, K.E., Shirey, R.S., Chen, A.R., McDonough, C. Lederman, H.M. (2001) Fatal warm autoimmune hemolytic anemia resulting from IgM autoagglutinins in an infant with severe combined immunodeficiency. Journal of Pediatric Hematology/Oncology, 23, 250 252.
11. Quartier, P., Brethon, B., Philippet, P., Landman-Parker, J., Le Deist, F. Fischer, A. (2001) Treatment of childhood autoimmune haemolytic anaemia with rituximab. Lancet, 3, 358, 1511 1513.
12. Quartier, P., Tournilhac, O., Archimbaud, C., Lazaro, L., Chaleteix, C., Millet, P., Peigue-Lafeuille, H., Blanche, S., Fischer, A., Casanova, J.L., Travade, P. Tardieu, M. (2003) Enteroviral meningoencephalitis after anti-CD20 (rituximab) treatment. Clinical Infectious Diseases, 36, e47 e49.
13. Rao, A., Kelly, M., Musselman, M., Ramadas, J., Wilson, D., Grossman, W. Shenoy, S. (2008) Safety, efficacy and immune reconstitution after Rituximab therapy in pediatric patients with chronic or refractory hematologic autoimmune cytopenias. Pediatric Blood & Cancer, 50, 822 825.
14. Teachey, D.T., Manno, C.S., Axsom, K.M., Andrews, T., Choi, J.K., Greenbaum, B.H., McMann, J.M., Sullivan, K.E., Travis, S.F. Grupp, S.A. (2005) Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS). Blood, 105, 2443 2448.
15. Zecca, M., Nobili, B., Ramenghi, U., Perrotta, S., Amendola, G., Rosito, P., Jankovic, M., Pierani, P., De Stefano, P., Regazzi Bonora, M. Locatelli, F. (2003) Rituximab for the treatment of refractory autoimmune hemolytic anemia in children. Blood, 15, 101.