Experimental infection of SPF pigs with Actinobacillus pleuropneumoniae serotype 9 alone or in association with Mycoplasma hyopneumoniae

Veterinary Microbiology

Volumn 135, Issue 3-4, 2009, Pages 283-291

  Marois, Corinne ^a   Gottschalk, Marcelo ^b   Morvan, Hervé ^c   Fablet, Christelle ^a   Madec, François ^a   Kobisch, Marylène ^a  

^a Healthy Pigs Production and Experimentation Section   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c Laboratoire de Developpement et d'Analyses des Cotes d'Armor   (France)

Author keywords

Actinobacillus pleuropneumoniae serotype 9; Dual infection; Experimental infection; Mycoplasma hyopneumoniae; SPF pigs

Indexed keywords

ACTINOBACILLUS INFECTION; ACTINOBACILLUS PLEUROPNEUMONIAE; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL INFECTION; FRANCE; MIXED INFECTION; MYCOPLASMA HYOPNEUMONIAE; MYCOPLASMOSIS; NONHUMAN; PIG FARMING; PNEUMONIA; SEROCONVERSION; SEROTYPE;

ACTINOBACILLUS INFECTIONS; ACTINOBACILLUS PLEUROPNEUMONIAE; ANIMALS; LUNG; MYCOPLASMA HYOPNEUMONIAE; PNEUMONIA OF SWINE, MYCOPLASMAL; SPECIFIC PATHOGEN-FREE ORGANISMS; SURVIVAL ANALYSIS; SWINE; SWINE DISEASES;

ACTINOBACILLUS PLEUROPNEUMONIAE; MYCOPLASMA; MYCOPLASMA HYOPNEUMONIAE; SUIDAE; SUS;

EID: 61849109334     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2008.09.061     Document Type: Article

References (29)

1. Cariolet R., Marie P., Moreau G., and Robert H. Rappel des différentes méthodes d'obtention de porcelets assainis: conditions de maintien du statut sanitaire et valorisation de ces animaux. Journées de la Recherche Porcine en France 26 (1994) 1-12
2. Chiers K., Donné E., Van Overbeke I., Ducatelle R., and Haesebrouck F. Actinobacillus pleuropneumoniae infections in closed swine herds: infection patterns and serological profiles. Vet. Microbiol. 85 (2002) 343-352
3. Chiers K., Donné E., Van Overbeke I., Ducatelle R., and Haesebrouck F. Evaluation of serology, bacteriological isolation and polymerase chain reaction for the detection of pigs carrying Actinobacillus pleuropneumoniae in the upper respiratory tract after experimental infection. Vet. Microbiol. 88 (2002) 385-392
4. Ciprián A., Cruz T.A., and de la Garza M. Mycoplasma hyopneumoniae: interaction with other agents in pigs, and evaluation of immunogens. Arch. Med. Res. 25 Summer (1994) 235-239
5. Cruijsen T.L., Van Leengoed L.A., Dekker-Nooren T.C., Schoevers E.J., and Verheijden J.H. Phagocytosis and killing of Actinobacillus pleuropneumoniae by alveolar macrophages and polymorphonuclear leukocytes isolated from pigs. Infect. Immun. 60 (1992) 4867-4871
6. Dubreuil J.D., Jacques M., Mittal K.R., and Gottschalk M. Actinobacillus pleuropneumoniae surface polysaccharides: their role in diagnosis and immunogenicity. Anim. Health. Res. Rev. 1 (2000) 73-93
7. Fano E., Pijoan C., and Dee S. Dynamics and persistence of Mycoplasma hyopneumoniae infection in pigs. Can. J. Vet. Res. 69 (2005) 223-228
8. Fittipaldi N., Broes A., Harel J., Kobisch M., and Gottschalk M. Evaluation and field validation of PCR tests for detection of Actinobacillus pleuropneumoniae in subclinically infected pigs. J. Clin. Microbiol. 41 (2003) 5085-5093
9. Frey J. Virulence in Actinobacillus pleuropneumoniae and RTX toxins. Trends Microbiol. 3 (1995) 257-261
10. Frey J., Bosse J.T., Chang Y.F., Cullen J.M., Fenwick B., Gerlach G.F., Gygi D., Haesebrouck F., Inzana T.J., Jansen R., Kamp E.M., Macdonald J., Macinnes J.I., Mittal K.R., Nicolet J., Rycroft A.N., Segers R.P.A.M., Smits M.A., Stenbaek E., Stuck D.K., Van Den Bosch J.F., Wilson P.J., and Young R. Actinobacillus pleuropneumoniae RTX toxins: uniform designation of haemolysins, cytolysins, pleurotoxin and their genes. J. Gen. Microbiol. 139 (1993) 1723-1728
11. Gottschalk M., Altman E., Charland N., De Lasalle F., and Dubreuil J.D. Evaluation of a saline boiled extract, capsular polysaccharides and long-chain lipopolysaccharides of Actinobacillus pleuropneumoniae serotype 1 as antigens for the serodiagnosis of swine pleuropneumonia. Vet. Microbiol. 42 (1994) 91-104
12. Gottschalk M., Morvan H., Broes A., Desrosiers R., and Kobisch M. Actualités sur la pleuropneumonie porcine. Journées de la Recherche Porcine 37 (2005) 341-346
13. Gottschalk M., and Taylor T. Actinobacillus pleuropneumoniae. In: Straw B.E., Zimmerman J.J., D'Allaire S., and Taylor D.J. (Eds). Diseases of Swine. ninth ed. (2006), Blackwell Publishing Ltd., Oxford, UK 563-576
14. Haesebrouck F., Chiers K., Van Overbeke I., and Ducatelle R. Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection. Vet. Microbiol. 58 (1997) 239-249
15. Jobert J.L., Savoye C., Cariolet R., Kobisch M., and Madec F. Experimental aerosol transmission of Actinobacillus pleuropneumoniae to pigs. Can. J. Vet. Res. 64 (2000) 21-26
16. Kobisch M., Labbé A., Morvan P., Le Moine M.M., Beaurepaire B., Cariolet R., and Pansart J.F. Pathologie pulmonaire du porc: un modèle expérimental associant Mycoplasma hyopneumoniae et Actinobacillus pleuropneumoniae. Journées de la Recherche Porcine 25 (1993) 339-344
17. Kobisch M., and Ross R.F. Experimental infections of swine. In: Tully J.G., and Razin S. (Eds). Molecular and Diagnostic Procedures in Mycoplasmology vol. II (1996), Academic Press, San Diego, CA 371-376
18. Krejci J., Nechvatalova K., Kudlackova H., Faldyna M., Kucerova Z., and Toman M. Systemic and local antibody responses after experimental infection with Actinobacillus pleuropneumoniae in piglets with passive or active immunity. J. Vet. Med. B Infect. Dis. Vet. Public Health. 52 (2005) 190-196
19. Kuhnert P., Berthoud H., Christensen H., Bisgaard M., and Frey J. Phylogenetic relationship of equine Actinobacillus species and distribution of RTX toxin genes among clusters. Vet. Res. 34 (2003) 353-359
20. Maas A., Jacobsen I.D., Meens J., and Gerlach G.F. Use of an Actinobacillus pleuropneumoniae multiple mutant as a vaccine that allows differentiation of vaccinated and infected animals. Infect. Immun. 74 (2006) 4124-4132
21. Madec F., and Derrien H. Fréquence, intensité et localisation des lésions pulmonaires chez le porc charcutier. Journées de la Recherche Porcine en France 13 (1981) 231-236
22. Maes D., Segales J., Meyns T., Sibila M., Pieters M., and Haesebrouck F. Control of Mycoplasma hyopneumoniae infections in pigs. Vet. Microbiol. 126 (2008) 297-309
23. Marois C., Le Carrou J., Kobisch M., and Gautier-Bouchardon A.V. Isolation of Mycoplasma hyopneumoniae from different sampling sites in experimentally infected and contact SPF piglets. Vet. Microbiol. 120 (2007) 96-104
24. Ross R.F. Mycoplasmal Diseases. In: Straw B.E., D'Allaire S., Mengeling W.L., and Taylor D.J. (Eds). Diseases of Swine. eighth ed. (1999), Iowa State University Press, Ames, IA 495-501
25. Savoye C., Jobert J.L., Berthelot-Hérault F., Keribin A.M., Cariolet R., Morvan H., Madec F., and Kobisch M. A PCR assay used to study aerosol transmission of Actinobacillus pleuropneumoniae from samples of live pigs under experimental conditions. Vet. Microbiol. 73 (2000) 337-347
26. Schaller A., Kuhn R., Kuhnert P., Nicolet J., Anderson T.J., MacInnes J.I., Segers R.P.A.M., and Frey J. Characterization of apxIVA, a new RTX determinant of Actinobacillus pleuropneumoniae. Microbiol. 145 (1999) 2105-2116
27. Thacker E.L. Mycoplasmal diseases. In: Straw B.E., Zimmerman J.J., D'Allaire S., and Taylor D.J. (Eds). Diseases of Swine. ninth ed. (2006), Blackwell Publishing Ltd., Oxford, UK 701-717
28. Verdin E., Saillard C., Labbe A., Bove J.M., and Kobisch M. A nested PCR assay for the detection of Mycoplasma hyopneumoniae in tracheobronchiolar washings from pigs. Vet. Microbiol. 76 (2000) 31-40
29. Yagihashi T., Nunoya T., Mitui T., and Tajima M. Effect of Mycoplasma hyopneumoniae infection on the development of Haemophilus pleuropneumoniae pneumonia in pigs. Nippon Juigaku Zasshi. 46 (1984) 705-713