The possible use of oximes as antidotal therapy in organophosphate-induced brain damage

NeuroToxicology

Volumn 30, Issue 2, 2009, Pages 167-173

  Shrot, Shai ^a   Markel, Gal ^a,b   Dushnitsky, Tsvika ^a   Krivoy, Amir ^a  

^a CBRN Medicine Branch   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

Author keywords

Brain; Central nervous system; HI 6; Nerve agent; Neurotoxicity; Pralidoxime

Indexed keywords

1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; ACETYLCHOLINESTERASE; ANTIDOTE; ATROPINE; HL 6; METHAMIDOPHOS; METHOXIME; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; METRIFONATE; OBIDOXIME; ORGANOPHOSPHATE; OXIME DERIVATIVE; PARAOXON; PRALIDOXIME; PYRIDOSTIGMINE; SARIN; SOMAN; TABUN; TRIMEDOXIME; UNCLASSIFIED DRUG; OXIME;

BLOOD BRAIN BARRIER; BLURRED VISION; BRAIN DAMAGE; BREATHING MUSCLE; DIZZINESS; DRUG BRAIN LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG PENETRATION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REACTIVATION; HUMAN; LD 50; NAUSEA; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; VOMITING; ANIMAL; BRAIN DAMAGE, CHRONIC; CHEMICALLY INDUCED; METABOLISM; ORGANOPHOSPHATE POISONING;

ANIMALS; ANTIDOTES; BRAIN DAMAGE, CHRONIC; HUMANS; ORGANOPHOSPHORUS COMPOUNDS; OXIMES; ORGANOPHOSPHATE POISONING;

EID: 61849104099     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2008.12.006     Document Type: Review

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