Pharmacokinetics and pharmacodynamics of porcine insulin zinc suspension in eight diabetic dogs

Veterinary Record

Volumn 164, Issue 8, 2009, Pages 232-237

  Fleeman, L M ^a,b   Rand, J S ^a,b   Morton, J M ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS; SUIDAE; SUS;

EID: 61849101441     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.164.8.232     Document Type: Article

References (27)

1. BESCH, W., WOLTANSKI, K. P., FISCHER, U., KOHNERT, K. D. & ZIEGLER, M. (1985) Measurement of plasma canine C-peptide by radioimmunoassay. Experimental and Clinical Endocrinology and Diabetes 86, 146-150
2. BLAND, J. M. & ALTMAN, D. G. (1999) Measuring agreement in method comparison studies. Statistical Methods in Medical Research 8, 135-160
3. BOYD, S. P., DAVISON, L. J., SLATER, L, WATSON, P. & CATCHPOLE, B. (2004) Measurement of serum C-peptide to assess pancreatic beta cell function in canine patients. Proceedings of the British Small Animal Veterinary Association Congress. Birmingham, April 1 to 4, 2004 p 520
4. CHINN, S. (1990) The assessment of methods of measurement. Statistics in Medicine 9, 351-362
5. CHURCH, D. B. (1981) The blood glucose response to three prolonged duration insulins in canine diabetes mellitus. Journal of Small Animal Practice 22, 301-310
6. CHURCH, D. B. (1982) Canine diabetes mellitus: some therapeutic considerations. Veterinary Annual 22, 235-240
7. DAVISON, L. J., RISTIC, J. M. E., HERRTAGE, M. E., RAMSEY, I. K. & CATCHPOLE, B. (2002) Anti-insulin antibodies in diabetic dogs treated with two different insulin preparations. Journal of Veterinary Internal Medicine 16, 636-637
8. FELDMAN, E. C. & NELSON, R. W. (2004) Canine diabetes mellitus. In Canine and Feline Endocrinology and Reproduction. 3rd edn. Elsevier, pp 486-538
9. FELDMAN, E. C, NELSON, R. W. & KARAM, J. H. (1983) Reduced immunogeniciry of pork insulin in dogs with spontaneous insulin-dependent diabetes mellitus (IDDM). Diabetes 32, 153A
10. FLEEMAN, L. M. & RAND, J. S. (2001a) Efficacy of intermittent low-dose heparinised saline flushes for maintaining indwelling peripheral and central intravenous catheters in diabetic dogs. Australian Veterinary Practitioner 31, 126-134
11. FLEEMAN, L. M. & RAND, J. S. (2001b) Management of canine diabetes. Veterinary Clinics of North America: Small Animal Practice 31, 855-880
12. FLEEMAN, L. M. & RAND, J. S. (2003) Evaluation of day-to-day variability of serial blood glucose curves in diabetic dogs. Journal of the American Veterinary Medical Association 222, 317-321
13. FRE1HERR VON BOLCSHAZY, G. (1999) Examination of immune reaction due to use of swine insulin in diabetic dogs. Proceedings of the World Small Animal Veterinary Association Conference. Lyon, September 23 to 29, 1999
14. GRAHAM, P. A., NASH, A. S. & MCKELLAR, Q. A. (1997) Pharmacokinetics of a porcine insulin sine suspension in diabetic dogs, Journal of Small Animal Practice 38, 434-438
15. HESS, R. S. & WARD, C. R. (2000) Effect of insulin dosage on glycemic response in dogs with diabetes mellitus: 221 cases (1993-1998). Journal of the American Veterinary Medical Association 216, 217-221
16. HORN, B. & MITTEN, R. W. (2000) Evaluation of an insulin zinc suspension for control of naturally occurring diabetes mellitus in dogs. Australian Veterinary Journal 78, 831-834
17. JENSEN, A. L, AAES, H., IVERSEN, L. & PETERSEN, T. K. (1999) The long-term biological variability of fasting plasma glucose and serum fructosamine in healthy beagle dogs. Veterinary Research Communications 23, 73-80
18. KAWANISHJ, K., N1SHINA, Y., ISHIDA, T., MACHIDA, S., YAMAMOTO, S., OFUJI, T., SAKURA, N. & YANAIHARA, N. (1980) Immunoreactive dog C-peptide level in the pancreatic vein. Hormone and Metabolic Research 12, 660-664
19. KWOK, S. C M., CHAN, S. J. & STEINER, D. F. (198.3) Cloning and nucleotide sequence analysis of the dog insulin gene: coded amino acid sequence of canine proinsulin predicts an additional C-peptide fragment. Journal of Biological Chemistry 258, 2.357-2363
20. MARSHALL, R. D., RAND, J. S. & MORTON, J. M. (2008) Glargine and protamine zinc insulin have a longer duration of action and result in lower mean daily glucose concentrations than lente insulin in healthy cats. Journal of Veterinary Pharmacology and Therapeutics 31, 205-212
21. MONTGOMERY, T. M., NELSON, R. W., FELDMAN, E. C, ROBERTSON, K. & POLONSKY, K. S. (1996) Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism. Journal of Veterinary Internal Medicine 10, 116-122
22. MUNROE, W. E., LAXTON, D., FALLIN, E. A., RICHTER, K. P., SANTEN, D. R., PANCIERA, D. L., TOWELL, T. L, WILLIAMS, K. A., HART, J. R., HILL, S., FINKLER, M. R. & SHINN, J. S. (2005) Efficacy and safety of a purified porcine insulin zinc suspension for managing diabetes mellitus in dogs. Journal of Veterinary Internal Medicine 19, 675-682
23. NEUBAUER, H. P. &SCHONE, H. H. (1978) The immunogeniciry of different insulins in several animal species. Diabetes 27, 8-15
24. PETERSON, J. D., NEHRLICH, S., OYER, P. E. & STEINER, D. F. (1972) Derermination of the amino acid sequence of the monkey, sheep, and dog proinsulin C-peptides by a semi-micro Edman degradation procedure. Journal of Biological Chemistry 247, 4866-4871
25. POLONSKY, K., JASPAN, J., PUCH, W., COHEN, D., SCHNEIDER, M., SCHWARTZ, T., MOOSSA, A. R., TAGER, H. & RUBENSTEIN, A. H. (1983) Metabolism of C- peptide in the dog. In vivo demonstration of the absence of hepatic extraction. Journal of Clinical Investigation 12, 1114-1123
26. ROWLAND, M. & TOZER, T. N. (1995) Appendix A: assessment of AUG In Clinical Pharmacokinetics: Concepts and Applications. 3rd edn. Lea & Febiger. pp 469-472
27. RUBENSTEIN, A. H., KUZUYA, H. & HORWITZ, D. L (1977) Clinical significance of circulating C-peptide in diabetes mellitus and hypoglycaemic disorders. Archives of Internal Medicine 137,625-632