Signaling components involved in Bcl-w-induced migration of gastric cancer cells

Cancer Letters

Volumn 277, Issue 1, 2009, Pages 22-28

  Bae, In Hwa ^a   Yoon, Sung Hwan ^a   Lee, Seung Bum ^a   Park, Jong Kuk ^a   Ho, Jin Nyoung ^a   Um, Hong Duck ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

Author keywords

Bcl w; Cell signaling; Gastric carcinoma; Migration

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN BCL W; UROKINASE;

ARTICLE; CANCER CELL; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STOMACH CANCER;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MATRIX METALLOPROTEINASE 2; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; STOMACH NEOPLASMS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 61849099995     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.11.022     Document Type: Article

References (23)

1. Gross A., McDonnell J.M., and Korsmeyer S.J. Bcl-2 family members and the mitochondria in apoptosis. Gene Dev. 13 (1999) 1899-1911
2. Antonsson B. Bax and other pro-apoptotic Bcl-2 family killer proteins and their victim, the mitochondrion. Cell Tissue Res. 306 (2001) 347-361
3. Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 (1998) 1322-1326
4. Uren R.T., Dewson G., Chen L., Coyne S.C., Huang D.C., Adams J.M., and Kluck R.M. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak. J. Cell Biol. 177 (2007) 277-287
5. Bae I.H., Park M.J., Yoon S.H., Kang S.W., Lee S.S., Choi K.M., and Um H.D. Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase Akt and Sp1. Cancer Res. 66 (2006) 4991-4995
6. Wilson J.W., Nostro M.C., Balzi M., Faraoni P., Cianchi F., Becciolini A., and Potten C.S. Bcl-w expression in colorectal adenocarcinoma. Brit. J. Cancer 82 (2000) 178-185
7. Hoelzinger D.B., Mariani L., Weis J., Woyke T., Berens T.J., McDonough W.S., Sloan A., Coons S.W., and Berens M.E. Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia 7 (2005) 7-16
8. Lee H.W., Lee S.S., Lee S.J., and Um H.D. Bcl-w is expressed in a majority of infiltrative gastric adenocarcinomas and suppresses the cancer cell death by blocking stress-activated protein kinase/c-Jun NH2-terminal kinase activation. Cancer Res. 63 (2003) 1093-1100
9. Legrand C., Polette M., Tournier J.M., de Bentamann S., Huet E., Monteau M., and Birembaut P. uPA/plasmin system-mediated MMP-9 activation is implicated in bronchial epithelial cell migration. Exp. Cell Res. 264 (2001) 326-336
10. Kunigal S., Gondi C.S., Gujrati M., Lakka S.S., Dinh D.H., Olivero W.C., and Rao J.S. SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA. Int. J. Oncol. 29 (2006) 1349-1357
11. Look M.P., van Putten W.L., Duffy M.J., Harbeck N., Christensen I.J., Thomssen C., Kates R., Spyratos F., Fernö M., Eppenberger-Castori S., Sweep C.G., Ulm K., Peyrat J.P., Martin P.M., Magdelenat H., Brünner N., Duggan C., Lisboa B.W., Bendahl P.O., Quillien V., Daver A., Ricolleau G., Meijer-van Gelder M.E., Manders P., Fiets W.E., Blankenstein M.A., Broët P., Romain S., Daxenbichler G., Windbichler G., Cufer T., Borstnar S., Kueng W., Beex L.V., Klinjn J.G., O'Higgins N., Eppenberger U., Jänicke F., Schmitt M., and Foekens J.A. Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. J. Natl. Cancer Inst. 94 (2002) 116-128
12. Hou Y., Okamoto C., Okada K., Kawao N., Kawata S., Ueshima S., and Matsuo O. C-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells. Cardiovasc. Res. 75 (2007) 186-194
13. Xing R.H., and Rabbani S.A. Regulation of urokinase production by androgens in human prostate cancer cells: effect on tumor growth and metastases in vivo. Endocrinology 140 (1999) 4056-4064
14. Krätzschmar J., Haendler B., Kojima S., Rifkin D.B., and Schleuning W.D. Bovine urokinase-type plasminogen activator and its receptor: cloning and induction by retinoic acid. Gene 125 (1993) 177-183
15. Dano K., Behrendt N., Høyer-Hansen G., Johnsen M., Lund L.R., Ploug M., and Romer J. Plasminogen activation and cancer. Thromb. Haemostasis 93 (2005) 676-681
16. Reuning U., Little S.P., Dixon E.P., Johnstone E.M., and Bang N.U. Molecular cloning of cDNA for the bovine urokinase-type plasminogen activator receptor. Thromb. Res. 72 (1993) 59-70
17. Gilmore A.P., and Romer L.H. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Biol. Cell 7 (1996) 1209-1224
18. Tang C.H., and Wei Y. The urokinase receptor and integrins in cancer progression. Cell. Mol. Life Sci. 65 (2008) 1916-1932
19. Park M.J., Kim M.S., Park I.C., Kang H.S., Yoo H., Park S.H., Rhee C.H., Hong S.I., and Lee S.H. PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. Cancer Res. 62 (2002) 6318-6322
20. Kim D.K., Cho E.S., Seong J.K., and Um H.D. Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway. J. Cell Sci. 114 (2001) 4329-4334
21. Schaller M.D., Hildebrand J.D., Schannon J.D., Fox J.W., Vines R.R., and Parsons J.T. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol. Cell. Biol. 14 (1994) 1680-1688
22. Tang H., Kerins D.M., Hao Q., Inagami T., and Vaughan D.E. The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells. J. Biol. Chem. 273 (1998) 18268-18272
23. Park H., Han I., Kwon H.J., and Oh E.S. Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells. Cancer Res. 65 (2005) 9899-9905