Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 7, 2009, Pages 1879-1882

  Koolman, Hannes ^b   Heinrich, Timo ^a   Böttcher, Henning ^a   Rautenberg, Wilfried ^a   Reggelin, Michael ^b  

^a MERCK KGAA   (Germany)

^b DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

4 Azaindole; c Met; Kinase inhibitor

Indexed keywords

INDOLE DERIVATIVE; NITRILE; PALLADIUM; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR;

ARTICLE; ARYLATION; CATALYSIS; CHEMICAL REACTION; CYCLIZATION; ENZYME INHIBITION; INHIBITION KINETICS; REACTION ANALYSIS; SYNTHESIS;

CATALYSIS; INDOLES; INHIBITORY CONCENTRATION 50; PALLADIUM; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MET;

EID: 61849093802     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.069     Document Type: Article

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