Assessment of vessel size by MRI in an orthotopic model of human pancreatic cancer

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Volumn , Issue , 2008, Pages 851-854

  Flexman, Jennifer A ^a   Yung, Andrew ^b   Yapp, Donald T T ^a   Ng, Sylvia S W ^a   Kozlowski, Piotr ^b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; BLOOD VESSELS; HEMODYNAMICS; IRON OXIDES; MAGNETIC RESONANCE IMAGING; RATE CONSTANTS; TUMORS; VOLUME FRACTION;

ANTI-ANGIOGENIC THERAPY; PANCREATIC CANCER XENOGRAFTS; PANCREATIC CANCERS; RELAXATION RATE CONSTANT; SUPERPARAMAGNETIC IRON OXIDES; TUMOR PROGRESSIONS; TUMOR VASCULATURE; VESSEL SIZE INDICES;

DISEASES;

ALGORITHM; ANIMAL; ARTICLE; BLOOD VESSEL; COMPUTER ASSISTED DIAGNOSIS; DISEASE MODEL; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PANCREAS TUMOR; PATHOLOGY; REPRODUCIBILITY; SCID MOUSE; SENSITIVITY AND SPECIFICITY; TUMOR CELL CULTURE; VASCULARIZATION;

ALGORITHMS; ANIMALS; BLOOD VESSELS; DISEASE MODELS, ANIMAL; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; ORGAN SIZE; PANCREATIC NEOPLASMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 61849090235     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/iembs.2008.4649287     Document Type: Conference Paper

References (10)

1. T. Welseh, J. kleeff, and H. Friess, "Molecular paihogenesis of pancreatic cancer: advances and challenges," Curr Mol Med, vol. 7, pp. 504-21, 2007.
2. S. R. Alberts, G. J. Gores, G. P. Kim, L. R. Roberts, M. L. kendrick. C. B. Rosen. S. T. Chari, and J. A. Martenson, "Treatment options for hepatobiliary and pancreatic cancer," Mayo Clin Proc, vol. 82, pp. 628-37, 2007.
3. N. Weidner, P. R. Carroll, J. Flax, W. Blumenfeld, and J. Folkmun, "Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma," Am J Pathol, vol. 143, pp. 401-9, 1993.
4. H. G. Hotz, O. J. Hines, R. Masood, B. Hotz, T. Foitzik, H. J. Buhr, P. S. Gill, and H. A. Reber, "VEGF antisense therapy inhibits tumor growth and improves survival in experimental pancreatic cancer," Surgery, vol. 137, pp. 192-9, 2005.
5. H. G. Hotz, H. A. Reber, B. Hotz, P. C. Sanghavi, T. Yu, T. Foitzik, H. J. Ruhr, and O. J. Hines, "Angiogenesis inhibitor TNP-470 reduces human pancreatic cancer growth," J Gastrointest Surg, vol. 5, pp. 131-8, 2001.
6. S. P. Robinson, C. Ludwig, J. Paulsson, and A. Ostman, "The effects of tumor-derived platelet-derived growth factor on vascular morphology and function in vivo revealed by susceptibility MRI," Int J Cancer, vol. 122, pp. 1548-56, 2008.
7. I. Tropres, S. Grimault, A. Vaeth, E. Grillon, C. Julien, J. F. Payen, L. Lamalle, and M. Decorps, "Vessel size imaging," Magn Reson Med, vol. 45, pp. 397-408, 2001.
8. T. P. Wade and P. kozlowski, "Longitudinal studies of angiogenesis in hormone-dependent Shionogi tumors," Neoplasia, vol. 9, pp. 563-8, 2007.
9. V. G. Kiselev, R. Strecker, S. Ziyeh, O. Speck, and J. Hennig, "Vessel size imaging in humans," Magn Reson Med, vol. 53, pp. 553-63, 2005.
10. S. S. Ng, M. S. Tsao, T. Nicklee, and D. W. Hedley, "Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice," Clin Cancer Res, vol. 7, pp. 3269-75, 2001