Differentiation of murine embryonic stem cells to thyrocytes requires insulin and insulin-like growth factor-1

Biochemical and Biophysical Research Communications

Volumn 381, Issue 2, 2009, Pages 264-270

  Arufe, Maria C ^a   Lu, Min ^a   Lin, Reigh Yi ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Embryonic stem cell; Insulin; Insulin like growth factor 1; Thyrocyte; Thyroid stimulating hormone

Indexed keywords

ACTIVIN A; COMPLEMENTARY DNA; ERGOCALCIFEROL; FIBRINOGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3BETA; SOMATOMEDIN C; THYROGLOBULIN; THYROTROPIN; THYROTROPIN RECEPTOR; TRANSCRIPTION FACTOR SOX17;

ANIMAL CELL; ARTICLE; BACTERIAL GENE; BODY BUILD; BODY HEIGHT; CELL AGGREGATION; CELL DEGENERATION; CELL DIFFERENTIATION; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MOTION; EMBRYONIC STEM CELL; ENDODERM; IN VITRO STUDY; MOUSE EMBRYO; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ACTIVINS; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; EMBRYONIC STEM CELLS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HMGB PROTEINS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MICE; RECEPTORS, THYROTROPIN; SOXF TRANSCRIPTION FACTORS; THYROID GLAND; THYROTROPIN;

MURINAE;

EID: 61849084169     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.02.035     Document Type: Article

References (14)

1. Keller G.M. In vitro differentiation of embryonic stem cells. Curr. Opin. Cell Biol. 7 (1995) 862-869
2. Lin R.Y., Kubo A., Keller G.M., and Davies T.F. Committing embryonic stem cells to differentiate into thyrocyte-like cells in vitro. Endocrinology 144 (2003) 2644-2649
3. Lin R.Y., and Davies T.F. Derivation and characterization of thyrocyte-like cells from embryonic stem cells in vitro. Methods Mol. Biol. 330 (2006) 249-261
4. Arufe M.C., Lu M., Kubo A., Keller G., Davies T.F., and Lin R.Y. Directed differentiation of mouse embryonic stem cells into thyroid follicular cells. Endocrinology 147 (2006) 3007-3015
5. Kubo A., Shinozaki K., Shannon J.M., Kouskoff V., Kennedy M., Woo S., Fehling H.J., and Keller G. Development of definitive endoderm from embryonic stem cells in culture. Development 131 (2004) 1651-1662
6. D'Amour K.A., Agulnick A.D., Eliazer S., Kelly O.G., Kroon E., and Baetge E.E. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23 (2005) 1534-1541
7. Jiang W., Shi Y., Zhao D., Chen S., Yong J., Zhang J., Qing T., Sun X., Zhang P., Ding M., Li D., and Deng H. In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res. 17 (2007) 333-344
8. Mfopou J.K., De Groote V., Xu X., Heimberg H., and Bouwens L. Sonic Hedgehog and other soluble factors from differentiating embryoid bodies inhibit pancreas development. Stem Cells 25 (2007) 1156-1165
9. Marians R.C., Ng L., Blair H.C., Unger P., Graves P.N., and Davies T.F. Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice. Proc. Natl. Acad. Sci. USA 99 (2002) 15776-15781
10. Rogers M.B., Hosler B.A., and Gudas L.J. Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes. Development 113 (1991) 815-824
11. Chieffi P., Picascia A., Stanzione R., Villone G., and Tramontano D. Endogenous insulin-like growth factors regulate the proliferation of TSH-independent mutants derived from FRTL5 cells. Biochimie 81 (1999) 367-371
12. Veneziani B.M., Di Marino C., Salvatore P., Villone G., Perrotti N., Frunzio R., and Tramontano D. Transfected insulin-like growth factor II modulates the mitogenic response of rat thyrocytes in culture. Mol. Cell. Endocrinol. 86 (1992) 11-20
13. Smerdely P., Pitsiavas V., and Boyages S.C. Methimazole inhibits FRTL5 thyroid cell proliferation by inducing S-phase arrest of the cell cycle. Endocrinology 133 (1993) 2403-2406
14. Postiglione M.P., Parlato R., Rodriguez-Mallon A., Rosica A., Mithbaokar P., Maresca M., Marians R.C., Davies T.F., Zannini M.S., De Felice M., and Di Lauro R. Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland. Proc. Natl. Acad. Sci. USA 99 (2002) 15462-15467