메뉴 건너뛰기




Volumn 15, Issue 4, 2009, Pages 421-431

Nonengraftment Haploidentical Cellular Immunotherapy for Refractory Malignancies: Tumor Responses without Chimerism

Author keywords

Bone marrow transplantation; Haploidentical; Immunotherapy; Radiation

Indexed keywords

CD3 ANTIGEN; CYCLOSPORIN A; GRANULOCYTE COLONY STIMULATING FACTOR; HLA ANTIGEN;

EID: 61749104445     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2008.12.503     Document Type: Article
Times cited : (64)

References (50)
  • 1
    • 0000161413 scopus 로고
    • The treatment of malignant tumors by repeated inoculations of erysipelas, with a report of ten original cases: 1893
    • Coley W.B. The treatment of malignant tumors by repeated inoculations of erysipelas, with a report of ten original cases: 1893. Am J Med Sci 105 (1893) 487-511
    • (1893) Am J Med Sci , vol.105 , pp. 487-511
    • Coley, W.B.1
  • 2
    • 0028081705 scopus 로고
    • Coley's toxins, tumor necrosis factor and cancer research: a historical perspective
    • Wiemann B., and Starnes C.O. Coley's toxins, tumor necrosis factor and cancer research: a historical perspective. Pharmacol Ther 64 (1994) 529-564
    • (1994) Pharmacol Ther , vol.64 , pp. 529-564
    • Wiemann, B.1    Starnes, C.O.2
  • 3
    • 0025678601 scopus 로고
    • Donor leukocyte transfusions for treatment of recurrent chronic myelogeneous leukemia in marrow transplant patients
    • Kolb H., Mittermuller J., and Clemm C. Donor leukocyte transfusions for treatment of recurrent chronic myelogeneous leukemia in marrow transplant patients. Blood 76 (1990) 2462-2465
    • (1990) Blood , vol.76 , pp. 2462-2465
    • Kolb, H.1    Mittermuller, J.2    Clemm, C.3
  • 4
    • 0015933422 scopus 로고
    • Graft-versus-leukemia: quantification of adoptive immunotherapy in murine leukemia
    • Bortin M.M., Rimm A.A., and Saltzstein E.C. Graft-versus-leukemia: quantification of adoptive immunotherapy in murine leukemia. Science 179 (1973) 811-813
    • (1973) Science , vol.179 , pp. 811-813
    • Bortin, M.M.1    Rimm, A.A.2    Saltzstein, E.C.3
  • 5
    • 0018126513 scopus 로고
    • Remission of relapsed leukemia during graft-versus-host reaction
    • Odom L., August C., and Githen J. Remission of relapsed leukemia during graft-versus-host reaction. Lancet 2 (1978) 537-540
    • (1978) Lancet , vol.2 , pp. 537-540
    • Odom, L.1    August, C.2    Githen, J.3
  • 6
    • 0018764352 scopus 로고
    • Anti-leukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow graft
    • Weiden P.L., Flourney N., Thomas E.D., et al. Anti-leukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow graft. New Engl J Med 300 (1979) 1068-1073
    • (1979) New Engl J Med , vol.300 , pp. 1068-1073
    • Weiden, P.L.1    Flourney, N.2    Thomas, E.D.3
  • 7
    • 0036374533 scopus 로고    scopus 로고
    • Correction of phenotype in a thalassemia mouse model using a nonmyeloablative marrow transplantation regimen
    • Bradley M.B., Sattler R.M., Raftopoulos H., et al. Correction of phenotype in a thalassemia mouse model using a nonmyeloablative marrow transplantation regimen. Biol Blood Marrow Transplant 8 (2002) 453-461
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 453-461
    • Bradley, M.B.1    Sattler, R.M.2    Raftopoulos, H.3
  • 8
    • 0030723985 scopus 로고    scopus 로고
    • Engraftment of hematopoietic stem cells in nonmyeloablated and myeloablated hosts
    • Quesenberry P.J., Stewart M.F., Peters S., et al. Engraftment of hematopoietic stem cells in nonmyeloablated and myeloablated hosts. Stem Cells 15 Suppl 1 (1997) 167-169
    • (1997) Stem Cells , vol.15 , Issue.SUPPL. 1 , pp. 167-169
    • Quesenberry, P.J.1    Stewart, M.F.2    Peters, S.3
  • 9
    • 0030979306 scopus 로고    scopus 로고
    • Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model
    • Nilsson S.K., Dooner M.S., Tiarks C.Y., et al. Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model. Blood 89 (1997) 4013-4020
    • (1997) Blood , vol.89 , pp. 4013-4020
    • Nilsson, S.K.1    Dooner, M.S.2    Tiarks, C.Y.3
  • 10
    • 0028564889 scopus 로고
    • Engraftment of normal murine marrow into nonmyeloablated host mice
    • Quesenberry P.J., Ramshaw H., Crittenden R.B., et al. Engraftment of normal murine marrow into nonmyeloablated host mice. Blood Cells 20 (1994) 348-350
    • (1994) Blood Cells , vol.20 , pp. 348-350
    • Quesenberry, P.J.1    Ramshaw, H.2    Crittenden, R.B.3
  • 11
    • 0029422528 scopus 로고
    • High levels of engraftment with a single infusion of bone marrow cells into normal unprepared mice
    • Ramshaw H.S., Crittenden R.B., Dooner M., et al. High levels of engraftment with a single infusion of bone marrow cells into normal unprepared mice. Biol Blood Marrow Transplant 1 (1995) 74-80
    • (1995) Biol Blood Marrow Transplant , vol.1 , pp. 74-80
    • Ramshaw, H.S.1    Crittenden, R.B.2    Dooner, M.3
  • 12
    • 0036270854 scopus 로고    scopus 로고
    • Engraftment of post-5-fluorouracil murine marrow into minimally myeloablated (100 cGy) murine hosts
    • D'Hondt L., Lambert J.F., Damon J., et al. Engraftment of post-5-fluorouracil murine marrow into minimally myeloablated (100 cGy) murine hosts. J Hematother Stem Cell Res 11 (2002) 483-490
    • (2002) J Hematother Stem Cell Res , vol.11 , pp. 483-490
    • D'Hondt, L.1    Lambert, J.F.2    Damon, J.3
  • 13
    • 0027263351 scopus 로고
    • Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice
    • Stewart F.M., Crittenden R.B., Lowry P.A., et al. Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice. Blood 81 (1993) 2566-2571
    • (1993) Blood , vol.81 , pp. 2566-2571
    • Stewart, F.M.1    Crittenden, R.B.2    Lowry, P.A.3
  • 14
    • 0032525077 scopus 로고    scopus 로고
    • Lymphohematopoietic engraftment in minimally myeloablated hosts
    • Stewart F.M., Zhong S., Wuu J., et al. Lymphohematopoietic engraftment in minimally myeloablated hosts. Blood 91 (1998) 3681-3687
    • (1998) Blood , vol.91 , pp. 3681-3687
    • Stewart, F.M.1    Zhong, S.2    Wuu, J.3
  • 15
    • 1542608429 scopus 로고    scopus 로고
    • Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biology
    • Colvin G.A., Lambert J.F., Abedi M., et al. Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biology. Leukemia 18 (2004) 575-583
    • (2004) Leukemia , vol.18 , pp. 575-583
    • Colvin, G.A.1    Lambert, J.F.2    Abedi, M.3
  • 16
    • 0037100412 scopus 로고    scopus 로고
    • Low-dose total body irradiation followed by allogeneic lymphocyte infusion may induce remission in patients with refractory hematologic malignancy
    • Ballen K.K., Becker P.S., Emmons R.B.V., et al. Low-dose total body irradiation followed by allogeneic lymphocyte infusion may induce remission in patients with refractory hematologic malignancy. Blood 100 (2002) 442-450
    • (2002) Blood , vol.100 , pp. 442-450
    • Ballen, K.K.1    Becker, P.S.2    Emmons, R.B.V.3
  • 17
    • 0019766649 scopus 로고
    • Alien-driven diversity and alien-selected escape: a rationale for allogeneic cancer immunotherapy
    • Sondel P.M., and Hank J.A. Alien-driven diversity and alien-selected escape: a rationale for allogeneic cancer immunotherapy. Transplant Proc 13 (1981) 1915-1921
    • (1981) Transplant Proc , vol.13 , pp. 1915-1921
    • Sondel, P.M.1    Hank, J.A.2
  • 18
    • 0018697639 scopus 로고
    • Graft-versus-leukemia activity induced by alloimmunization without augmentation of graft-versus-host activity
    • Bortin M.M., Truitt R.L., Rimm A.A., et al. Graft-versus-leukemia activity induced by alloimmunization without augmentation of graft-versus-host activity. Nature 281 (1979) 490-491
    • (1979) Nature , vol.281 , pp. 490-491
    • Bortin, M.M.1    Truitt, R.L.2    Rimm, A.A.3
  • 19
    • 0025100777 scopus 로고
    • Graft-versus-leukemia reactions after bone marrow transplantation
    • Horowitz M.M., Gale R.P., Sondel P.M., et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 75 (1990) 555-562
    • (1990) Blood , vol.75 , pp. 555-562
    • Horowitz, M.M.1    Gale, R.P.2    Sondel, P.M.3
  • 20
    • 0028963088 scopus 로고
    • Immunodominant minor histocompatibility antigens expressed by mouse leukemic cells can serve as effective targets for T cell immunotherapy
    • Pion S., Fontaine P., Baron C., et al. Immunodominant minor histocompatibility antigens expressed by mouse leukemic cells can serve as effective targets for T cell immunotherapy. J Clin Invest 95 (1995) 1561-1568
    • (1995) J Clin Invest , vol.95 , pp. 1561-1568
    • Pion, S.1    Fontaine, P.2    Baron, C.3
  • 21
    • 0020745304 scopus 로고
    • Adoptive immunotherapy of disseminated malignancies. Role of alien histocompatibility antigens on cancer cells and effectiveness of cells from alloimmunized donors
    • Tempelis L.D., Wasik M.R., and Bortin M.M. Adoptive immunotherapy of disseminated malignancies. Role of alien histocompatibility antigens on cancer cells and effectiveness of cells from alloimmunized donors. Ric Clin Lab 13 (1983) 163-182
    • (1983) Ric Clin Lab , vol.13 , pp. 163-182
    • Tempelis, L.D.1    Wasik, M.R.2    Bortin, M.M.3
  • 22
    • 0020691120 scopus 로고
    • Transplantation for severe combined immunodeficiency with HLA-A, -B, -D, and -DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells
    • Reisner Y., Kapoor N., Kirkpatrick D., et al. Transplantation for severe combined immunodeficiency with HLA-A, -B, -D, and -DR incompatible parental marrow cells fractionated by soybean agglutinin and sheep red blood cells. Blood 61 (1983) 341-348
    • (1983) Blood , vol.61 , pp. 341-348
    • Reisner, Y.1    Kapoor, N.2    Kirkpatrick, D.3
  • 23
    • 0023225236 scopus 로고
    • Engraftment following T-cell-depleted marrow transplantation, I: the role of major and minor histocompatibility barriers
    • Ferrara J., Lipton J., Hellman S., et al. Engraftment following T-cell-depleted marrow transplantation, I: the role of major and minor histocompatibility barriers. Transplantation 43 (1987) 461-467
    • (1987) Transplantation , vol.43 , pp. 461-467
    • Ferrara, J.1    Lipton, J.2    Hellman, S.3
  • 24
    • 0023180173 scopus 로고
    • Thymus and B cell reconstitution in severe combined immunodeficiency after transplantation of monoclonal antibody-depleted parental mismatched bone marrow
    • Hong R., Horowitz S., Moen R., et al. Thymus and B cell reconstitution in severe combined immunodeficiency after transplantation of monoclonal antibody-depleted parental mismatched bone marrow. Bone Marrow Transplant 4 (1987) 405-409
    • (1987) Bone Marrow Transplant , vol.4 , pp. 405-409
    • Hong, R.1    Horowitz, S.2    Moen, R.3
  • 25
    • 0032558759 scopus 로고    scopus 로고
    • Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype
    • Aversa F., Tabilio A., Velardi A., et al. Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype. N Engl J Med 339 (1998) 1186-1193
    • (1998) N Engl J Med , vol.339 , pp. 1186-1193
    • Aversa, F.1    Tabilio, A.2    Velardi, A.3
  • 26
    • 12144286211 scopus 로고    scopus 로고
    • Haploidentical stem cell transplantation with purified CD34 cells after a chemotherapy-alone conditioning regimen
    • Lacerda J.F., Martins C., Carmo J.A., et al. Haploidentical stem cell transplantation with purified CD34 cells after a chemotherapy-alone conditioning regimen. Biol Blood Marrow Transplant 9 (2003) 633-642
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 633-642
    • Lacerda, J.F.1    Martins, C.2    Carmo, J.A.3
  • 27
    • 20644470338 scopus 로고    scopus 로고
    • Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse
    • Aversa F., Terenzi A., Tabilio A., et al. Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse. J Clin Oncol 23 (2005) 3447-3454
    • (2005) J Clin Oncol , vol.23 , pp. 3447-3454
    • Aversa, F.1    Terenzi, A.2    Tabilio, A.3
  • 28
    • 21144458592 scopus 로고    scopus 로고
    • In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem cell transplantation without ex vivo graft manipulation
    • Kanda Y., Oshima K., Asano-Mori Y., et al. In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem cell transplantation without ex vivo graft manipulation. Transplantation 79 (2005) 1351-1357
    • (2005) Transplantation , vol.79 , pp. 1351-1357
    • Kanda, Y.1    Oshima, K.2    Asano-Mori, Y.3
  • 29
    • 12144289378 scopus 로고    scopus 로고
    • Nonmyeloablative bone marrow transplantation: infectious complications in 65 recipients of HLA-identical and mismatched transplants
    • Daly A., McAfee S., Dey B., et al. Nonmyeloablative bone marrow transplantation: infectious complications in 65 recipients of HLA-identical and mismatched transplants. Biol Blood Marrow Transplant 9 (2003) 373-382
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 373-382
    • Daly, A.1    McAfee, S.2    Dey, B.3
  • 30
    • 7444224095 scopus 로고    scopus 로고
    • Facilitating T-cell immune reconstitution after haploidentical transplantation in adults
    • Waller E.K., Giver C.R., Rosenthal H., et al. Facilitating T-cell immune reconstitution after haploidentical transplantation in adults. Blood Cells Mol Dis 33 (2004) 233-237
    • (2004) Blood Cells Mol Dis , vol.33 , pp. 233-237
    • Waller, E.K.1    Giver, C.R.2    Rosenthal, H.3
  • 31
    • 0028843985 scopus 로고
    • Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease
    • Pan L., Delmonte Jr. J., Jalonen C.K., et al. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease. Blood 86 (1995) 4422-4429
    • (1995) Blood , vol.86 , pp. 4422-4429
    • Pan, L.1    Delmonte Jr., J.2    Jalonen, C.K.3
  • 32
    • 0030922090 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation
    • Zeng D., Dejbakhsh-Jones S., and Strober S. Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation. Blood 90 (1997) 453-463
    • (1997) Blood , vol.90 , pp. 453-463
    • Zeng, D.1    Dejbakhsh-Jones, S.2    Strober, S.3
  • 33
    • 0037818348 scopus 로고    scopus 로고
    • G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for transplantation and autoimmune diseases
    • Franzke A., Piao W., Lauber J., et al. G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for transplantation and autoimmune diseases. Blood 102 (2003) 734-739
    • (2003) Blood , vol.102 , pp. 734-739
    • Franzke, A.1    Piao, W.2    Lauber, J.3
  • 34
    • 0024537269 scopus 로고
    • Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma
    • Anasetti C., Amos D., Beatty P.G., et al. Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma. New Engl J Med 320 (1989) 197-204
    • (1989) New Engl J Med , vol.320 , pp. 197-204
    • Anasetti, C.1    Amos, D.2    Beatty, P.G.3
  • 35
    • 0025316254 scopus 로고
    • Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells
    • Sykes M., Romick M.L., and Sachs D.H. Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells. Proc Natl Acad Sci U S A 87 (1990) 5633-5637
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5633-5637
    • Sykes, M.1    Romick, M.L.2    Sachs, D.H.3
  • 36
    • 0036720416 scopus 로고    scopus 로고
    • Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells
    • Mapara M.Y., Yong-Mi K., Sheng-Ping W., et al. Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood 100 (2002) 1903-1909
    • (2002) Blood , vol.100 , pp. 1903-1909
    • Mapara, M.Y.1    Yong-Mi, K.2    Sheng-Ping, W.3
  • 37
    • 0033642531 scopus 로고    scopus 로고
    • The intentional induction of mixed chimerism and achievement of anti-tumor responses following non-myeloablative conditioning therapy and HLA-matched donor marrow transplantation for refractory hematologic malignancies
    • Spitzer T.R., McAfee S., Sackstein R., et al. The intentional induction of mixed chimerism and achievement of anti-tumor responses following non-myeloablative conditioning therapy and HLA-matched donor marrow transplantation for refractory hematologic malignancies. Biol Blood Marrow Transplant 6 (2000) 309-320
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 309-320
    • Spitzer, T.R.1    McAfee, S.2    Sackstein, R.3
  • 38
    • 0141475940 scopus 로고    scopus 로고
    • Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogenieic bone marrow transplantation
    • Dey B.R., McAfee S., Colby C., et al. Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogenieic bone marrow transplantation. Biol Blood Marrow Transplant 9 (2003) 320-329
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 320-329
    • Dey, B.R.1    McAfee, S.2    Colby, C.3
  • 39
    • 13444310503 scopus 로고    scopus 로고
    • Anti-tumor response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation
    • Dey B.R., McAfee S., Colby C.D., et al. Anti-tumor response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol 128 (2005) 351-359
    • (2005) Br J Haematol , vol.128 , pp. 351-359
    • Dey, B.R.1    McAfee, S.2    Colby, C.D.3
  • 40
    • 0014530949 scopus 로고
    • The requirement of more than one antigenic determinant for immunogenicity
    • Rajewsky K., Schirrmacher V., Nase S., et al. The requirement of more than one antigenic determinant for immunogenicity. J Exp Med 129 (1969) 1131-1143
    • (1969) J Exp Med , vol.129 , pp. 1131-1143
    • Rajewsky, K.1    Schirrmacher, V.2    Nase, S.3
  • 41
    • 0015251655 scopus 로고
    • Resistance of guinea pigs to leukemia following transfer of immunocompetent allogeneic lymphoid cells
    • Katz D.H., Ellman L., Paul W.E., et al. Resistance of guinea pigs to leukemia following transfer of immunocompetent allogeneic lymphoid cells. Cancer Res 32 (1972) 133-140
    • (1972) Cancer Res , vol.32 , pp. 133-140
    • Katz, D.H.1    Ellman, L.2    Paul, W.E.3
  • 42
    • 0015256213 scopus 로고
    • Mechanisms involved in the antileukemic effect of immunocompetent allogeneic lymphoid cell transfer
    • Ellman L., Katz D.H., Green I., et al. Mechanisms involved in the antileukemic effect of immunocompetent allogeneic lymphoid cell transfer. Cancer Res 32 (1972) 141-148
    • (1972) Cancer Res , vol.32 , pp. 141-148
    • Ellman, L.1    Katz, D.H.2    Green, I.3
  • 43
    • 41849090799 scopus 로고    scopus 로고
    • The allogeneic effect revisited: exogenous help for endogenous, tumor-specific T cells
    • Symons H.J., Levy M.Y., Wang J., et al. The allogeneic effect revisited: exogenous help for endogenous, tumor-specific T cells. Biol Blood Marrow Transplant 14 (2008) 499-509
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 499-509
    • Symons, H.J.1    Levy, M.Y.2    Wang, J.3
  • 44
    • 0141455935 scopus 로고    scopus 로고
    • Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusion in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma
    • Rubio M.T., Kim Y.M., Sachs T., et al. Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusion in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma. Blood 102 (2003) 2300-2307
    • (2003) Blood , vol.102 , pp. 2300-2307
    • Rubio, M.T.1    Kim, Y.M.2    Sachs, T.3
  • 45
    • 0030474065 scopus 로고    scopus 로고
    • + cells are responsible for the rapid elimination of allogeneic donor lymphoid cells
    • + cells are responsible for the rapid elimination of allogeneic donor lymphoid cells. J Immunol 157 (1996) 4805-4810
    • (1996) J Immunol , vol.157 , pp. 4805-4810
    • Fast, L.D.1
  • 46
    • 4444219513 scopus 로고    scopus 로고
    • Exploiting alloreactivity for tumour immunotherapy
    • Stauss H., Xue S., Gillmore R., et al. Exploiting alloreactivity for tumour immunotherapy. Vox Sang 87 Suppl 2 (2004) 227-229
    • (2004) Vox Sang , vol.87 , Issue.SUPPL. 2 , pp. 227-229
    • Stauss, H.1    Xue, S.2    Gillmore, R.3
  • 47
    • 0019367613 scopus 로고
    • Sensitization of lymphocytes against pooled allogeneic cells, II: characterization of effector cells cytotoxic for autologous lymphoblastoid cell lines
    • Zarling J., Bach F., and Kung P. Sensitization of lymphocytes against pooled allogeneic cells, II: characterization of effector cells cytotoxic for autologous lymphoblastoid cell lines. J Immunol 126 (1981) 375-378
    • (1981) J Immunol , vol.126 , pp. 375-378
    • Zarling, J.1    Bach, F.2    Kung, P.3
  • 48
    • 0020591033 scopus 로고
    • Human anti-lymphoma responses generated in vitro and in vivo following sensitization by allogeneic leukocytes
    • Zarling J., Kay N., Grant B., et al. Human anti-lymphoma responses generated in vitro and in vivo following sensitization by allogeneic leukocytes. Cancer Immunol Immunother 5 (1983) 237-239
    • (1983) Cancer Immunol Immunother , vol.5 , pp. 237-239
    • Zarling, J.1    Kay, N.2    Grant, B.3
  • 49
    • 0034254243 scopus 로고    scopus 로고
    • + cells are effective alloantigen-presenting cells
    • + cells are effective alloantigen-presenting cells. Blood 96 (2000) 1144-1149
    • (2000) Blood , vol.96 , pp. 1144-1149
    • Fast, L.D.1
  • 50
    • 0028964905 scopus 로고
    • Transient increase in circulating donor leukocytes after allogeneic transfusions in immunocompetent recipients compatible with donor cell proliferation
    • Lee T.H., Donegan E., Slichter S., et al. Transient increase in circulating donor leukocytes after allogeneic transfusions in immunocompetent recipients compatible with donor cell proliferation. Blood 85 (1995) 1207-1214
    • (1995) Blood , vol.85 , pp. 1207-1214
    • Lee, T.H.1    Donegan, E.2    Slichter, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.