Bone structure and remodelling in stroke patients: Early effects of zoledronate

Bone

Volumn 44, Issue 4, 2009, Pages 629-633

  Poole, Kenneth E S ^a   Vedi, Shobna ^a   Debiram, Irene ^a   Rose, Collette ^a   Power, Jon ^a   Loveridge, Nigel ^a   Warburton, Elizabeth A ^b   Reeve, Jonathan ^a   Compston, Juliet ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Bone formation; Bone resorption; Histomorphometry; Stroke; Zoledronate

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; PLACEBO; ZOLEDRONIC ACID;

ADULT; AGED; ARTICLE; BONE BIOPSY; BONE DENSITY; BONE REMODELING; BONE STRUCTURE; BONE TURNOVER; CANCELLOUS BONE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; FLUORESCENCE MICROSCOPY; HIP; HUMAN; HUMAN TISSUE; ILIAC BONE; MALE; MORPHOMETRICS; OSSIFICATION; OSTEOCLAST; OSTEOID; OSTEOLYSIS; POROSITY; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; STROKE; STROKE PATIENT; THICKNESS;

ABSORPTIOMETRY, PHOTON; AGED; AGED, 80 AND OVER; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; BONE REMODELING; DIPHOSPHONATES; FEMALE; HEMIPLEGIA; HIP; HUMANS; ILIUM; IMIDAZOLES; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; OSTEOCLASTS; OSTEOPOROSIS; STROKE;

EID: 61749102969     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.11.017     Document Type: Article

References (25)

1. Poole K.E., Loveridge N., Rose C.M., Warburton E.A., and Reeve J. A single infusion of zoledronate prevents bone loss after stroke. Stroke 38 (2007) 1519-1525
2. Sato Y., Kuno H., Kaji M., Etoh K., and Oizumi K. Influence of immobilization upon calcium metabolism in the week following hemiplegic stroke. J. Neurol. Sci. 175 (2000) 135-139
3. Sato Y., Kuno H., Kaji M., Ohshima Y., Asoh T., and Oizumi K. Increased bone resorption during the first year after stroke. Stroke 29 (1998) 1373-1377
4. Sato Y., Iwamoto J., Kanoko T., and Satoh K. Risedronate therapy for prevention of hip fracture after stroke in elderly women. Neurology 64 (2005) 811-816
5. Jorgensen L., Jacobsen B.K., Wilsgaard T., and Magnus J.H. Walking after stroke: does it matter? Changes in bone mineral density within the first 12 months after stroke. A longitudinal study. Osteoporos. Int. 11 (2000) 381-387
6. Sato Y., Kaji M., Saruwatari N., and Oizumi K. Hemiosteoporosis following stroke: importance of pathophysiologic understanding and histologic evidence. Stroke 30 (1999) 1978-1979
7. Poole K.E., Loveridge N., Barker P.J., et al. Reduced vitamin D in acute stroke. Stroke 37 (2006) 243-245
8. Sato Y., Asoh T., Kaji M., and Oizumi K. Beneficial effect of intermittent cyclical etidronate therapy in hemiplegic patients following an acute stroke. J. Bone Miner. Res. 15 (2000) 2487-2494
9. Mahoney F., and Barthel D. Functional evaluation: the Barthel Index. Maryland State Med. J. 14 (1965) 56-61
10. Scandinavian Stroke Study Group. Multicenter trial of hemodilution in ischemic stroke-background and study protocol. Stroke 16 (1985) 885-890
11. Frost H.M. Tetracycline-based histological analysis of bone remodeling. Calcif. Tissue Res. 3 (1969) 211-237
12. Poole K.E., van Bezooijen R.L., Loveridge N., et al. Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation. Faseb J. 19 (2005) 1842-1844
13. Farquharson C., Whitehead C., Rennie S., Thorp B., and Loveridge N. Cell proliferation and enzyme activities associated with the development of avian tibial dyschondroplasia: an in situ biochemical study. Bone 13 (1992) 59-67
14. Vedi S., Compston J.E., Webb A., and Tighe J.R. Histomorphometric analysis of bone biopsies from the iliac crest of normal British subjects. Metab. Bone Dis. Relat. Res. 4 (1982) 231-236
15. Garrahan N.J., Mellish R.W.E., and Compston J.E. A new method for the analysis of two-dimensional trabecular bone structure in human iliac crest biopsies. J. Microsc. 142 (1986) 341-349
16. Freemont A.J. Bone histomorphometry. In: Tovey F.I., and Stamp T.C.B. (Eds). The measurement of metabolic bone disease (1995), Parthenon Publishing Group Ltd 77-90
17. Foldes J., Shih M.S., and Parfitt A.M. Frequency distributions of tetracycline-based measurements: implications for the interpretation of bone formation indices in the absence of double-labeled surfaces. J. Bone Miner. Res. 5 (1990) 1063-1067
18. Kragstrup J., Gundersen H.J., Melsen F., and Mosekilde L. Estimation of the three-dimensional wall thickness of completed remodeling sites in iliac trabecular bone. Metab. Bone Dis. Relat. Res. 4 (1982) 113-119
19. Parfitt A.M., Drezner M.K., Glorieux F.H., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2 (1987) 595-610
20. Parfitt A.M. The physiologic and clinical significance of bone histomorphometric data. In: RR R (Ed). Bone Histomorphometry (1983), CRC Press, London 143-223
21. Recker R.R., Delmas P.D., Halse J., et al. The effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure. J. Bone Miner. Res. (2007)
22. Ramnemark A., Nyberg L., Lorentzon R., Englund U., and Gustafson Y. Progressive hemiosteoporosis on the paretic side and increased bone mineral density in the nonparetic arm the first year after severe stroke. Osteoporos. Int. 9 (1999) 269-275
23. Poole K.E., Reeve J., and Warburton E.A. Falls, fractures, and osteoporosis after stroke: time to think about protection?. Stroke 33 (2002) 1432-1436
24. Poole K.E.S., Warburton E.A., and Reeve J. Rapid long-term bone loss following stroke in a man with osteoporosis and atherosclerosis. Osteoporos. Int. 16 (2005) 302-305
25. Sato Y., Kaji M., Honda Y., et al. Abnormal calcium homeostasis in disabled stroke patients with low 25-hydroxyvitamin D. Bone 34 (2004) 710-715