-
1
-
-
0017739457
-
Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues
-
ArnoldWP, Aldred R, Murad F (1977a) Cigarette smoke activates guanylate cyclase and increases guanosine 3',5'-monophosphate in tissues. Science 198:934-936
-
(1977)
Science
, vol.198
, pp. 934-936
-
-
Arnold, W.P.1
Aldred, R.2
Murad, F.3
-
2
-
-
0000707453
-
Nitric oxide activates guanylate cyclase and increases guanosine 3' : 5'-cyclic monophosphate levels in various tissue preparations
-
Arnold WP, Mittal CK, Katsuki S, Murad F (1977b) Nitric oxide activates guanylate cyclase and increases guanosine 3' : 5'-cyclic monophosphate levels in various tissue preparations. Proc Natl Acad Sci U S A 74:3203-3207
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 3203-3207
-
-
Arnold, W.P.1
Mittal, C.K.2
Katsuki, S.3
Murad, F.4
-
4
-
-
33748686575
-
Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
-
Bender AT, Beavo JA (2006) Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488-520
-
(2006)
Pharmacol Rev
, vol.58
, pp. 488-520
-
-
Bender, A.T.1
Beavo, J.A.2
-
5
-
-
0036021103
-
Cardiac HCN channels: Structure, function, and modulation
-
Biel M, Schneider A, Wahl C (2002) Cardiac HCN channels: structure, function, and modulation. Trends Cardiovasc Med 12:206-212
-
(2002)
Trends Cardiovasc Med
, vol.12
, pp. 206-212
-
-
Biel, M.1
Schneider, A.2
Wahl, C.3
-
6
-
-
40849096004
-
The GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP
-
Biswas KH, Sopory S, Visweswariah SS (2008) The GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP. Biochemistry 47 (11):3534-3543
-
(2008)
Biochemistry
, vol.47
, Issue.11
, pp. 3534-3543
-
-
Biswas, K.H.1
Sopory, S.2
Visweswariah, S.S.3
-
7
-
-
0025968704
-
Expression of soluble guanylate cyclase activity requires both enzyme subunits
-
Buechler WA, Nakane M, Murad F (1991) Expression of soluble guanylate cyclase activity requires both enzyme subunits. Biochem Biophys Res Commun 174:351-357
-
(1991)
Biochem Biophys Res Commun
, vol.174
, pp. 351-357
-
-
Buechler, W.A.1
Nakane, M.2
Murad, F.3
-
8
-
-
0347364629
-
Gi protein activation in intact cells involves subunit rearrangement rather than dissociation
-
Bünemann M, Frank M, Lohse MJ (2003) Gi protein activation in intact cells involves subunit rearrangement rather than dissociation. Proc Natl Acad Sci U S A 100:16077-16082
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 16077-16082
-
-
Bünemann, M.1
Frank, M.2
Lohse, M.J.3
-
9
-
-
33646795266
-
Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes
-
Castro LR, Verde I, Cooper DM, Fischmeister R (2006) Cyclic guanosine monophosphate compartmentation in rat cardiac myocytes. Circulation 113:2221-2228
-
(2006)
Circulation
, vol.113
, pp. 2221-2228
-
-
Castro, L.R.1
Verde, I.2
Cooper, D.M.3
Fischmeister, R.4
-
10
-
-
33947197650
-
Nitric oxide-evoked transient kinetics of cyclic GMP in vascular smooth muscle cells
-
DostmannWR
-
Cawley SM, Sawyer CL, Brunelle KF, van der Vliet A, DostmannWR (2007) Nitric oxide-evoked transient kinetics of cyclic GMP in vascular smooth muscle cells. Cell Signal 19:1023-1033
-
(2007)
Cell Signal
, vol.19
, pp. 1023-1033
-
-
Cawley, S.M.1
Sawyer, C.L.2
Brunelle, K.F.3
van der Vliet, A.4
-
11
-
-
0024507556
-
A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor
-
Chinkers M, Garbers DL, Chang MS, Lowe DG, Chin HM, Goeddel DV, Schulz S (1989) A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor. Nature 338:78-83
-
(1989)
Nature
, vol.338
, pp. 78-83
-
-
Chinkers, M.1
Garbers, D.L.2
Chang, M.S.3
Lowe, D.G.4
Chin, H.M.5
Goeddel, D.V.6
Schulz, S.7
-
12
-
-
34447265905
-
Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling
-
Conti M, Beavo J (2007) Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem 76:481-511
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 481-511
-
-
Conti, M.1
Beavo, J.2
-
13
-
-
33645313112
-
CNG and HCN channels: Two peas, one pod
-
Craven KB, Zagotta WN (2006) CNG and HCN channels: two peas, one pod. Annu Rev Physiol 68:375-401
-
(2006)
Annu Rev Physiol
, vol.68
, pp. 375-401
-
-
Craven, K.B.1
Zagotta, W.N.2
-
14
-
-
15944381871
-
Function of cGMP-dependent protein kinases in the nervous system
-
Feil R, Hofmann F, Kleppisch T (2005) Function of cGMP-dependent protein kinases in the nervous system. Rev Neurosci 16:23-41
-
(2005)
Rev Neurosci
, vol.16
, pp. 23-41
-
-
Feil, R.1
Hofmann, F.2
Kleppisch, T.3
-
15
-
-
33749665081
-
Compartmentation of cyclic nucleotide signaling in the heart: The role of cyclic nucleotide phosphodiesterases
-
Fischmeister R, Castro LR, Abi-Gerges A, Rochais F, Jurevicius J, Leroy J, Vandecasteele G (2006) Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases. Circ Res 99:816-828
-
(2006)
Circ Res
, vol.99
, pp. 816-828
-
-
Fischmeister, R.1
Castro, L.R.2
Abi-Gerges, A.3
Rochais, F.4
Jurevicius, J.5
Leroy, J.6
Vandecasteele, G.7
-
16
-
-
34250653301
-
Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase
-
Friebe A, Mergia E, Dangel O, Lange A, Koesling D (2007) Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase. Proc Natl Acad Sci U S A 104:7699-7704
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7699-7704
-
-
Friebe, A.1
Mergia, E.2
Dangel, O.3
Lange, A.4
Koesling, D.5
-
17
-
-
0019195506
-
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
-
Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376
-
(1980)
Nature
, vol.288
, pp. 373-376
-
-
Furchgott, R.F.1
Zawadzki, J.V.2
-
18
-
-
33645798851
-
The fluorescent toolbox for assessing protein location and function
-
Giepmans BN, Adams SR, Ellisman MH, Tsien RY (2006) The fluorescent toolbox for assessing protein location and function. Science 312:217-224
-
(2006)
Science
, vol.312
, pp. 217-224
-
-
Giepmans, B.N.1
Adams, S.R.2
Ellisman, M.H.3
Tsien, R.Y.4
-
19
-
-
0025001895
-
Expression of soluble guanylyl cyclase. Catalytic activity requires two enzyme subunits
-
Harteneck C, Koesling D, Soling A, Schultz G, Bohme E (1990) Expression of soluble guanylyl cyclase. Catalytic activity requires two enzyme subunits. FEBS Lett 272:221-223
-
(1990)
FEBS Lett
, vol.272
, pp. 221-223
-
-
Harteneck, C.1
Koesling, D.2
Soling, A.3
Schultz, G.4
Bohme, E.5
-
20
-
-
0035979721
-
Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone
-
He X, Chow D, Martick MM, Garcia KC (2001) Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone. Science 293:1657-1662
-
(2001)
Science
, vol.293
, pp. 1657-1662
-
-
He, X.1
Chow, D.2
Martick, M.M.3
Garcia, K.C.4
-
21
-
-
28644443374
-
Dynamics of receptor/G protein coupling in living cells
-
Hein P, Frank M, Hoffmann C, Lohse MJ, Bünemann M (2005) Dynamics of receptor/G protein coupling in living cells. EMBO J 24:4106-4114
-
(2005)
EMBO J
, vol.24
, pp. 4106-4114
-
-
Hein, P.1
Frank, M.2
Hoffmann, C.3
Lohse, M.J.4
Bünemann, M.5
-
22
-
-
34548263094
-
Phosphodiesterase type 2 and the homeostasis of cyclic GMP in living thalamic neurons
-
Hepp R, Tricoire L, Hu E, Gervasi N, Paupardin-Tritsch D, Lambolez B, Vincent P (2007) Phosphodiesterase type 2 and the homeostasis of cyclic GMP in living thalamic neurons. J Neurochem 102:1875-1886
-
(2007)
J Neurochem
, vol.102
, pp. 1875-1886
-
-
Hepp, R.1
Tricoire, L.2
Hu, E.3
Gervasi, N.4
Paupardin-Tritsch, D.5
Lambolez, B.6
Vincent, P.7
-
23
-
-
38349174744
-
Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in Platelets
-
Hoffmeister M, Riha P, Neumuller O, Danielewski O, Schultess J, Smolenski AP (2008) Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in Platelets. J Biol Chem 283:2297-2306
-
(2008)
J Biol Chem
, vol.283
, pp. 2297-2306
-
-
Hoffmeister, M.1
Riha, P.2
Neumuller, O.3
Danielewski, O.4
Schultess, J.5
Smolenski, A.P.6
-
24
-
-
33644834949
-
Function of cGMP-dependent protein kinases as revealed by gene deletion
-
Hofmann F, Feil R, Kleppisch T, Schlossmann J (2006) Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev 86:1-23
-
(2006)
Physiol Rev
, vol.86
, pp. 1-23
-
-
Hofmann, F.1
Feil, R.2
Kleppisch, T.3
Schlossmann, J.4
-
25
-
-
0035956940
-
Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
-
Honda A, Adams SR, Sawyer CL, Lev-Ram V, Tsien RY, Dostmann WR (2001) Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator. Proc Natl Acad Sci U S A 98:2437-2442
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2437-2442
-
-
Honda, A.1
Adams, S.R.2
Sawyer, C.L.3
Lev-Ram, V.4
Tsien, R.Y.5
Dostmann, W.R.6
-
26
-
-
33645160262
-
Membrane-permeable cygnets: Rapid cellular internalization of fluorescent cGMP-indicators
-
Honda A, Moosmeier MA, Dostmann WR (2005a) Membrane-permeable cygnets: rapid cellular internalization of fluorescent cGMP-indicators. Front Biosci 10:1290-1301
-
(2005)
Front Biosci
, vol.10
, pp. 1290-1301
-
-
Honda, A.1
Moosmeier, M.A.2
Dostmann, W.R.3
-
27
-
-
24644512357
-
Cygnets: In vivo characterization of novel cGMP indicators and in vivo imaging of intracellular cGMP
-
Honda A, Sawyer CL, Cawley SM, Dostmann WR (2005b) Cygnets: in vivo characterization of novel cGMP indicators and in vivo imaging of intracellular cGMP. Methods Mol Biol 307: 27-43
-
(2005)
Methods Mol Biol
, vol.307
, pp. 27-43
-
-
Honda, A.1
Sawyer, C.L.2
Cawley, S.M.3
Dostmann, W.R.4
-
28
-
-
0023505509
-
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
-
Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A 84:9265-9269
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 9265-9269
-
-
Ignarro, L.J.1
Buga, G.M.2
Wood, K.S.3
Byrns, R.E.4
Chaudhuri, G.5
-
29
-
-
0031979719
-
Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels
-
Jain L, Chen XJ, Brown LA, Eaton DC (1998) Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels. Am J Physiol 274:L475-L484
-
(1998)
Am J Physiol
, vol.274
-
-
Jain, L.1
Chen, X.J.2
Brown, L.A.3
Eaton, D.C.4
-
31
-
-
0022887257
-
Soluble guanylate cyclase from rat lung exists as a heterodimer
-
Kamisaki Y, Saheki S, Nakane M, Palmieri JA, Kuno T, Chang BY,Waldman SA, Murad F (1986) Soluble guanylate cyclase from rat lung exists as a heterodimer. J Biol Chem 261:7236-7241
-
(1986)
J Biol Chem
, vol.261
, pp. 7236-7241
-
-
Kamisaki, Y.1
Saheki, S.2
Nakane, M.3
Palmieri, J.A.4
Kuno, T.5
Chang, B.Y.6
Waldman, S.A.7
Murad, F.8
-
33
-
-
0036301043
-
Cyclic nucleotide-gated ion channels
-
Kaupp UB, Seifert R (2002) Cyclic nucleotide-gated ion channels. Physiol Rev 82:769-824
-
(2002)
Physiol Rev
, vol.82
, pp. 769-824
-
-
Kaupp, U.B.1
Seifert, R.2
-
34
-
-
0024323201
-
Adenylyl cyclase amino acid sequence: Possible channel- or transporterlike structure
-
Krupinski J, Coussen F, Bakalyar HA, Tang WJ, Feinstein PG, Orth K, Slaughter C, Reed RR, Gilman AG (1989) Adenylyl cyclase amino acid sequence: possible channel- or transporterlike structure. Science 244:1558-1564
-
(1989)
Science
, vol.244
, pp. 1558-1564
-
-
Krupinski, J.1
Coussen, F.2
Bakalyar, H.A.3
Tang, W.J.4
Feinstein, P.G.5
Orth, K.6
Slaughter, C.7
Reed, R.R.8
Gilman, A.G.9
-
35
-
-
0142056753
-
Structure, regulation, and function of mammalian membrane guanylyl cyclase receptors, with a focus on guanylyl cyclase-A
-
Kuhn M (2003) Structure, regulation, and function of mammalian membrane guanylyl cyclase receptors, with a focus on guanylyl cyclase-A. Circ Res 93:700-709
-
(2003)
Circ Res
, vol.93
, pp. 700-709
-
-
Kuhn, M.1
-
36
-
-
24744455039
-
2+ and cAMP signaling in the insulinsecreting MIN6 beta -cell line
-
2+ and cAMP signaling in the insulinsecreting MIN6 beta -cell line. J Biol Chem 280:31294-31302
-
(2005)
J Biol Chem
, vol.280
, pp. 31294-31302
-
-
Landa Jr, L.R.1
Harbeck, M.2
Kaihara, K.3
Chepurny, O.4
Kitiphongspattana, K.5
Graf, O.6
Nikolaev, V.O.7
Lohse, M.J.8
Holz, G.G.9
Roe, M.W.10
-
37
-
-
0022531550
-
Phosphorylation of cGMP-dependent protein kinase increases the affinity for cyclic AMP
-
Landgraf W, Hullin R, Gobel C, Hofmann F (1986) Phosphorylation of cGMP-dependent protein kinase increases the affinity for cyclic AMP. Eur J Biochem 154:113-117
-
(1986)
Eur J Biochem
, vol.154
, pp. 113-117
-
-
Landgraf, W.1
Hullin, R.2
Gobel, C.3
Hofmann, F.4
-
38
-
-
0033680726
-
The gain of rod phototransduction: Reconciliation of biochemical and electrophysiological measurements
-
Leskov IB, Klenchin VA, Handy JW, Whitlock GG, Govardovskii VI, Bownds MD, Lamb TD, Pugh EN, Jr, Arshavsky VY (2000) The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron 27:525-537
-
(2000)
Neuron
, vol.27
, pp. 525-537
-
-
Leskov, I.B.1
Klenchin, V.A.2
Handy, J.W.3
Whitlock, G.G.4
Govardovskii, V.I.5
Bownds, M.D.6
Lamb, T.D.7
Pugh Jr, E.N.8
Arshavsky, V.Y.9
-
39
-
-
0029445432
-
cGMP signaling through cAMP- and cGMP-dependent protein kinases
-
Lincoln TM, Komalavilas P, Boerth NJ, MacMillan-Crow LA, Cornwell TL (1995) cGMP signaling through cAMP- and cGMP-dependent protein kinases. Adv Pharmacol 34:305-322
-
(1995)
Adv Pharmacol
, vol.34
, pp. 305-322
-
-
Lincoln, T.M.1
Komalavilas, P.2
Boerth, N.J.3
MacMillan-Crow, L.A.4
Cornwell, T.L.5
-
40
-
-
35248892144
-
Monitoring receptor signaling by intramolecular FRET
-
Lohse MJ, Bünemann M, Hoffmann C, Vilardaga JP, Nikolaev VO (2007) Monitoring receptor signaling by intramolecular FRET. Curr Opin Pharmacol 7:547-553
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 547-553
-
-
Lohse, M.J.1
Bünemann, M.2
Hoffmann, C.3
Vilardaga, J.P.4
Nikolaev, V.O.5
-
41
-
-
39949085589
-
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors
-
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bünemann M (2008) Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci 29:159-165
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 159-165
-
-
Lohse, M.J.1
Nikolaev, V.O.2
Hein, P.3
Hoffmann, C.4
Vilardaga, J.P.5
Bünemann, M.6
-
42
-
-
35348976560
-
2+ non-canonical pathway
-
2+ non-canonical pathway. J Biol Chem 282:28980-28990
-
(2007)
J Biol Chem
, vol.282
, pp. 28980-28990
-
-
Ma, L.1
Wang, H.Y.2
-
43
-
-
0036790852
-
The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
-
Martinez SE, Wu AY, Glavas NA, Tang XB, Turley S, Hol WG, Beavo JA (2002) The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding. Proc Natl Acad Sci U S A 99:13260-13265
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13260-13265
-
-
Martinez, S.E.1
Wu, A.Y.2
Glavas, N.A.3
Tang, X.B.4
Turley, S.5
Hol, W.G.6
Beavo, J.A.7
-
44
-
-
9144259249
-
Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice
-
Massberg S, Gruner S, Konrad I, Garcia Arguinzonis MI, Eigenthaler M, Hemler K, Kersting J, Schulz C, Muller I, Besta F, Nieswandt B, Heinzmann U, Walter U, Gawaz M (2004) Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice. Blood 103:136-142
-
(2004)
Blood
, vol.103
, pp. 136-142
-
-
Massberg, S.1
Gruner, S.2
Konrad, I.3
Garcia Arguinzonis, M.I.4
Eigenthaler, M.5
Hemler, K.6
Kersting, J.7
Schulz, C.8
Muller, I.9
Besta, F.10
Nieswandt, B.11
Heinzmann, U.12
Walter, U.13
Gawaz, M.14
-
45
-
-
0037343944
-
Visualization of the spatial and temporal dynamics of intracellular signaling
-
Miyawaki A (2003) Visualization of the spatial and temporal dynamics of intracellular signaling. Dev Cell 4:295-305
-
(2003)
Dev Cell
, vol.4
, pp. 295-305
-
-
Miyawaki, A.1
-
46
-
-
3142723295
-
FRET-based analysis of cAMP dynamics in live cells reveals distinct functions of compartmentalized phosphodiesterases in cardiac myocytes
-
Mongillo M, Evellin S, Lissandron V, Terrin A, Hannawacker A, Lohse MJ, Pozzan T, Houslay M, Zaccolo M (2004) FRET-based analysis of cAMP dynamics in live cells reveals distinct functions of compartmentalized phosphodiesterases in cardiac myocytes. Circ Res 95:67-75
-
(2004)
Circ Res
, vol.95
, pp. 67-75
-
-
Mongillo, M.1
Evellin, S.2
Lissandron, V.3
Terrin, A.4
Hannawacker, A.5
Lohse, M.J.6
Pozzan, T.7
Houslay, M.8
Zaccolo, M.9
-
47
-
-
33644865929
-
Compartmentalized phosphodiesterase- 2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway
-
Mongillo M, Tocchetti CG, Terrin A, Lissandron V, Cheung YF, Dostmann WR, Pozzan T, Kass DA, Paolocci N, HouslayMD, ZaccoloM(2006) Compartmentalized phosphodiesterase- 2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway. Circ Res 98:226-234
-
(2006)
Circ Res
, vol.98
, pp. 226-234
-
-
Mongillo, M.1
Tocchetti, C.G.2
Terrin, A.3
Lissandron, V.4
Cheung, Y.F.5
Dostmann, W.R.6
Pozzan, T.7
Kass, D.A.8
Paolocci, N.9
HouslayMD10
ZaccoloM11
-
49
-
-
0035129282
-
A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein
-
Nakai J, Ohkura M, Imoto K (2001) A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein. Nat Biotechnol 19:137-141
-
(2001)
Nat Biotechnol
, vol.19
, pp. 137-141
-
-
Nakai, J.1
Ohkura, M.2
Imoto, K.3
-
50
-
-
38349099574
-
Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors
-
Nausch LW, Ledoux J, Bonev AD, Nelson MT, Dostmann WR (2008) Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors. Proc Natl Acad Sci U S A 105:365-370
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 365-370
-
-
Nausch, L.W.1
Ledoux, J.2
Bonev, A.D.3
Nelson, M.T.4
Dostmann, W.R.5
-
51
-
-
33646737382
-
Monitoring of cAMP synthesis and degradation in living cells
-
Nikolaev VO, Lohse MJ (2006) Monitoring of cAMP synthesis and degradation in living cells. Physiology (Bethesda) 21:86-92
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 86-92
-
-
Nikolaev, V.O.1
Lohse, M.J.2
-
52
-
-
4444377903
-
Novel single chain cAMP sensors for receptor-induced signal propagation
-
Nikolaev VO, Bünemann M, Hein L, Hannawacker A, Lohse MJ (2004) Novel single chain cAMP sensors for receptor-induced signal propagation. J Biol Chem 279:37215-37218
-
(2004)
J Biol Chem
, vol.279
, pp. 37215-37218
-
-
Nikolaev, V.O.1
Bünemann, M.2
Hein, L.3
Hannawacker, A.4
Lohse, M.J.5
-
53
-
-
12544251544
-
Real-time monitoring of the PDE2 activity of live cells: Hormone-stimulated cAMP hydrolysis is faster than hormonestimulated cAMP synthesis
-
Nikolaev VO, Gambaryan S, Engelhardt S, Walter U, Lohse MJ (2005) Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormonestimulated cAMP synthesis. J Biol Chem 280:1716-1719
-
(2005)
J Biol Chem
, vol.280
, pp. 1716-1719
-
-
Nikolaev, V.O.1
Gambaryan, S.2
Engelhardt, S.3
Walter, U.4
Lohse, M.J.5
-
55
-
-
31344471740
-
Fluorescent sensors for rapid monitoring of intracellular cGMP
-
Nikolaev VO, Gambaryan S, Lohse MJ (2006b) Fluorescent sensors for rapid monitoring of intracellular cGMP. Nat Methods 3:23-25
-
(2006)
Nat Methods
, vol.3
, pp. 23-25
-
-
Nikolaev, V.O.1
Gambaryan, S.2
Lohse, M.J.3
-
56
-
-
33847068206
-
Overview of PDEs and their regulation
-
Omori K, Kotera J (2007) Overview of PDEs and their regulation. Circ Res 100:309-327
-
(2007)
Circ Res
, vol.100
, pp. 309-327
-
-
Omori, K.1
Kotera, J.2
-
57
-
-
0032601591
-
Structure and function of cGMP-dependent protein kinases
-
Pfeifer A, Ruth P, Dostmann W, Sausbier M, Klatt P, Hofmann F (1999) Structure and function of cGMP-dependent protein kinases. Rev Physiol Biochem Pharmacol 135:105-149
-
(1999)
Rev Physiol Biochem Pharmacol
, vol.135
, pp. 105-149
-
-
Pfeifer, A.1
Ruth, P.2
Dostmann, W.3
Sausbier, M.4
Klatt, P.5
Hofmann, F.6
-
58
-
-
33646343978
-
Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)
-
Pfleger KD, Eidne KA (2006) Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat Methods 3:165-174
-
(2006)
Nat Methods
, vol.3
, pp. 165-174
-
-
Pfleger, K.D.1
Eidne, K.A.2
-
59
-
-
33745646054
-
Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments
-
Piggott LA, Hassell KA, Berkova Z, Morris AP, Silberbach M, Rich TC (2006) Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments. J Gen Physiol 128:3-14
-
(2006)
J Gen Physiol
, vol.128
, pp. 3-14
-
-
Piggott, L.A.1
Hassell, K.A.2
Berkova, Z.3
Morris, A.P.4
Silberbach, M.5
Rich, T.C.6
-
60
-
-
0035794170
-
Guanylyl cyclase-linked natriuretic peptide receptors: Structure and regulation
-
Potter LR, Hunter T (2001) Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulation. J Biol Chem 276:6057-6060
-
(2001)
J Biol Chem
, vol.276
, pp. 6057-6060
-
-
Potter, L.R.1
Hunter, T.2
-
61
-
-
0027407602
-
Amplification and kinetics of the activation steps in phototransduction
-
Pugh EN, Jr, Lamb TD (1993) Amplification and kinetics of the activation steps in phototransduction. Biochim Biophys Acta 1141:111-149
-
(1993)
Biochim Biophys Acta
, vol.1141
, pp. 111-149
-
-
Pugh Jr, E.N.1
Lamb, T.D.2
-
62
-
-
10444235057
-
Soluble guanylyl cyclase: More secrets revealed
-
Pyriochou A, Papapetropoulos A (2005) Soluble guanylyl cyclase: more secrets revealed. Cell Signal 17:407-413
-
(2005)
Cell Signal
, vol.17
, pp. 407-413
-
-
Pyriochou, A.1
Papapetropoulos, A.2
-
63
-
-
0036449453
-
Cyclic AMP sensors in living cells: What signals can they actually measure?
-
Rich TC, Karpen JW (2002) Cyclic AMP sensors in living cells: what signals can they actually measure? Ann Biomed Eng 30:1088-1099
-
(2002)
Ann Biomed Eng
, vol.30
, pp. 1088-1099
-
-
Rich, T.C.1
Karpen, J.W.2
-
64
-
-
0033895842
-
Cyclic nucleotidegated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion
-
Rich TC, Fagan KA, Nakata H, Schaack J, Cooper DM, Karpen JW (2000) Cyclic nucleotidegated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion. J Gen Physiol 116:147-161
-
(2000)
J Gen Physiol
, vol.116
, pp. 147-161
-
-
Rich, T.C.1
Fagan, K.A.2
Nakata, H.3
Schaack, J.4
Cooper, D.M.5
Karpen, J.W.6
-
65
-
-
0034942107
-
In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors
-
Rich TC, Tse TE, Rohan JG, Schaack J, Karpen JW (2001) In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors. J Gen Physiol 118:63-78
-
(2001)
J Gen Physiol
, vol.118
, pp. 63-78
-
-
Rich, T.C.1
Tse, T.E.2
Rohan, J.G.3
Schaack, J.4
Karpen, J.W.5
-
66
-
-
10644280705
-
Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: An in vivo study using adenovirus-mediated expression of CNG channels
-
Rochais F, Vandecasteele G, Lefebvre F, Lugnier C, Lum H,Mazet JL, Cooper DM, Fischmeister R (2004) Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels. J Biol Chem 279:52095-52105
-
(2004)
J Biol Chem
, vol.279
, pp. 52095-52105
-
-
Rochais, F.1
Vandecasteele, G.2
Lefebvre, F.3
Lugnier, C.4
Lum, H.5
Mazet, J.L.6
Cooper, D.M.7
Fischmeister, R.8
-
67
-
-
10044276844
-
NO activation of guanylyl cyclase
-
Russwurm M, Koesling D (2004) NO activation of guanylyl cyclase. Embo J 23:4443-4450
-
(2004)
Embo J
, vol.23
, pp. 4443-4450
-
-
Russwurm, M.1
Koesling, D.2
-
68
-
-
35148812231
-
Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: A systematic approach
-
Russwurm M, Mullershausen F, Friebe A, Jager R, Russwurm C, Koesling D (2007) Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach. Biochem J 407:69-77
-
(2007)
Biochem J
, vol.407
, pp. 69-77
-
-
Russwurm, M.1
Mullershausen, F.2
Friebe, A.3
Jager, R.4
Russwurm, C.5
Koesling, D.6
-
69
-
-
0042859823
-
Cyclic GMP phosphodiesterases and regulation of smooth muscle function
-
Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA (2003) Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ Res 93:280-291
-
(2003)
Circ Res
, vol.93
, pp. 280-291
-
-
Rybalkin, S.D.1
Yan, C.2
Bornfeldt, K.E.3
Beavo, J.A.4
-
70
-
-
0034671963
-
Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Ialpha and green fluorescent proteins
-
Sato M, Hida N, Ozawa T, Umezawa Y (2000) Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Ialpha and green fluorescent proteins. Anal Chem 72:5918-5924
-
(2000)
Anal Chem
, vol.72
, pp. 5918-5924
-
-
Sato, M.1
Hida, N.2
Ozawa, T.3
Umezawa, Y.4
-
71
-
-
26844450450
-
Imaging the nanomolar range of nitric oxide with an amplifiercoupled fluorescent indicator in living cells
-
Sato M, Hida N, Umezawa Y (2005) Imaging the nanomolar range of nitric oxide with an amplifiercoupled fluorescent indicator in living cells. Proc Natl Acad Sci U S A 102:14515-14520
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14515-14520
-
-
Sato, M.1
Hida, N.2
Umezawa, Y.3
-
72
-
-
33845527724
-
Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells
-
Sato M, Nakajima T, Goto M, Umezawa Y (2006) Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells. Anal Chem 78:8175-8182
-
(2006)
Anal Chem
, vol.78
, pp. 8175-8182
-
-
Sato, M.1
Nakajima, T.2
Goto, M.3
Umezawa, Y.4
-
73
-
-
0344874560
-
Cygnets: Spatial and temporal analysis of intracellular cGMP
-
DostmannWR
-
Sawyer CL, Honda A, DostmannWR(2003) Cygnets: spatial and temporal analysis of intracellular cGMP. Proc West Pharmacol Soc 46:28-31
-
(2003)
Proc West Pharmacol Soc
, vol.46
, pp. 28-31
-
-
Sawyer, C.L.1
Honda, A.2
-
74
-
-
18944382189
-
cGMP-dependent protein kinases in drug discovery
-
Schlossmann J, Hofmann F (2005) cGMP-dependent protein kinases in drug discovery. Drug Discov Today 10:627-634
-
(2005)
Drug Discov Today
, vol.10
, pp. 627-634
-
-
Schlossmann, J.1
Hofmann, F.2
-
75
-
-
0017795758
-
Fluorescence energy transfer as a spectroscopic ruler
-
Stryer L (1978) Fluorescence energy transfer as a spectroscopic ruler. Annu Rev Biochem 47: 819-846
-
(1978)
Annu Rev Biochem
, vol.47
, pp. 819-846
-
-
Stryer, L.1
-
76
-
-
19944428363
-
cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism
-
Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA (2005) cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Circ Res 96:100-109
-
(2005)
Circ Res
, vol.96
, pp. 100-109
-
-
Takimoto, E.1
Champion, H.C.2
Belardi, D.3
Moslehi, J.4
Mongillo, M.5
Mergia, E.6
Montrose, D.C.7
Isoda, T.8
Aufiero, K.9
Zaccolo, M.10
Dostmann, W.R.11
Smith, C.J.12
Kass, D.A.13
-
77
-
-
33645232527
-
2+ indicator GCaMP2
-
2+ indicator GCaMP2. Proc Natl Acad Sci U S A 103:4753-4758
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4753-4758
-
-
Tallini, Y.N.1
Ohkura, M.2
Choi, B.R.3
Ji, G.4
Imoto, K.5
Doran, R.6
Lee, J.7
Plan, P.8
Wilson, J.9
Xin, H.B.10
Sanbe, A.11
Gulick, J.12
Mathai, J.13
Robbins, J.14
Salama, G.15
Nakai, J.16
Kotlikoff, M.I.17
-
78
-
-
0038729670
-
Measurement of the millisecond activation switch of G-protein-coupled receptors in living cells
-
LohseMJ
-
Vilardaga JP, Bünemann M, Krasel C, Castro M, LohseMJ (2003) Measurement of the millisecond activation switch of G-protein-coupled receptors in living cells. Nat Biotechnol 21:807-812
-
(2003)
Nat Biotechnol
, vol.21
, pp. 807-812
-
-
Vilardaga, J.P.1
Bünemann, M.2
Krasel, C.3
Castro, M.4
-
79
-
-
14844312091
-
A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway
-
Wunder F, Stasch JP, Hutter J, Alonso-Alija C, Huser J, Lohrmann E (2005a) A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway. Anal Biochem 339:104-112
-
(2005)
Anal Biochem
, vol.339
, pp. 104-112
-
-
Wunder, F.1
Stasch, J.P.2
Hutter, J.3
Alonso-Alija, C.4
Huser, J.5
Lohrmann, E.6
-
80
-
-
27844464469
-
Characterization of the first potent and selective PDE9 inhibitor using a cGMP reporter cell line
-
Wunder F, Tersteegen A, Rebmann A, Erb C, Fahrig T, Hendrix M (2005b) Characterization of the first potent and selective PDE9 inhibitor using a cGMP reporter cell line. Mol Pharmacol 68:1775-1781
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1775-1781
-
-
Wunder, F.1
Tersteegen, A.2
Rebmann, A.3
Erb, C.4
Fahrig, T.5
Hendrix, M.6
-
81
-
-
33947276805
-
A cell-based nitric oxide reporter assay useful for the identification and characterization of modulators of the nitric oxide/guanosine 3',5'-cyclic monophosphate pathway
-
Wunder F, Buehler G, Huser J, Mundt S, Bechem M, Kalthof B (2007) A cell-based nitric oxide reporter assay useful for the identification and characterization of modulators of the nitric oxide/guanosine 3',5'-cyclic monophosphate pathway. Anal Biochem 363:219-227
-
(2007)
Anal Biochem
, vol.363
, pp. 219-227
-
-
Wunder, F.1
Buehler, G.2
Huser, J.3
Mundt, S.4
Bechem, M.5
Kalthof, B.6
-
82
-
-
1842841350
-
Use of chimeric fluorescent proteins and fluorescence resonance energy transfer to monitor cellular responses
-
Zaccolo M (2004) Use of chimeric fluorescent proteins and fluorescence resonance energy transfer to monitor cellular responses. Circ Res 94:866-873
-
(2004)
Circ Res
, vol.94
, pp. 866-873
-
-
Zaccolo, M.1
|