Unresectable hepatocellular carcinoma: Serial early vascular and cellular changes after transarterial chemoembolization as detected with MR imaging

Radiology

Volumn 250, Issue 2, 2009, Pages 466-473

  Kamel, Ihab R ^a   Liapi, Eleni ^a   Reyes, Diane K ^a   Zahurak, Marianna ^a   Bluemke, David A ^a   Geschwind, Jean François H ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOXORUBICIN; GADODIAMIDE; MITOMYCIN C; MUTAMYCIN C; UNCLASSIFIED DRUG; CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM;

ADULT; AGED; ARTICLE; CHEMOEMBOLIZATION; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTRAST ENHANCEMENT; DIFFUSION COEFFICIENT; ECHO PLANAR IMAGING; FEMALE; FOLLOW UP; HUMAN; LIVER CELL CARCINOMA; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT ASSESSMENT; PORTAL VEIN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIODIAGNOSIS; THREE DIMENSIONAL IMAGING; TREATMENT RESPONSE; TUMOR VOLUME; LIVER; LIVER TUMOR; METHODOLOGY; MIDDLE AGED; PATHOLOGY; REGRESSION ANALYSIS; TREATMENT OUTCOME; VASCULARIZATION;

CARCINOMA, HEPATOCELLULAR; CHEMOEMBOLIZATION, THERAPEUTIC; CONTRAST MEDIA; FEMALE; GADOLINIUM; HUMANS; LIVER; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; TREATMENT OUTCOME;

EID: 61749090699     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2502072222     Document Type: Article

References (30)

1. El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999;340:745-750.
2. American Cancer Society. Cancer facts and figures. Atlanta, Ga: American Cancer Society, 2006.
3. Carr BI. Hepatic artery chemoembolization for advanced stage HCC: experience of 650 patients. Hepatogastroenterology 2002;49: 79-86.
4. Ahmed M, Goldberg SN. Thermal ablation therapy for hepatocellular carcinoma. J Vasc Interv Radiol 2002;13(9 pt 2):S231-S244.
5. Ramsey DE, Kernagis LY, Soulen MC, Geschwind JF. Chemoembolization of hep- atocellular carcinoma. J Vasc Interv Radiol 2002;13(9 pt 2):S211-S221.
6. Bruix J, Llovet JM, Castells A, et al. Transar- terial embolization versus symptomatic treatment in patients with advanced hepato- cellular carcinoma: results of a randomized, controlled trial in a single institution. Hepatology 1998;27:1578-1583.
7. Rilling WS, Drooz A. Multidisciplinary management of hepatocellular carcinoma. J Vasc Interv Radiol 2002;13(9 pt 2):S259-S263.
8. Head HW, Dodd GD 3rd. Thermal ablation for hepatocellular carcinoma. Gastroenterology 2004;127(5 suppl 1):S167-S178.
9. Bruix J, Sala M, Llovet JM. Chemoemboliza- tion for hepatocellular carcinoma. Gastroenterology 2004;127(5 suppl 1):S179-S188.
10. Solomon B, Soulen MC, Baum RA, Haskal ZJ, Shlansky-Goldberg RD, Cope C. Chemo- embolization of hepatocellular carcinoma with cisplatin, doxorubicin, mitomycin-C, ethiodol, and polyvinyl alcohol: prospective evaluation of response and survival in a U.S. population. J Vasc Interv Radiol 1999;10: 793-798.
11. Soulen MC. Chemoembolization of hepatic malignancies. Oncology (Williston Park) 1994;8:77- 84.
12. Nakamura H, Hashimoto T, Oi H, Sawada S. Transcatheter oily chemoembolization of hepatocellular carcinoma. Radiology 1989; 170:783-786.
13. Ngan H, Lai CL, Fan ST, Lai EC, Yuen WK, Tso WK. Transcatheter arterial chemoem- bolization in inoperable hepatocellular carcinoma: 4-year follow-up. J Vasc Interv Radiol 1996;7:419- 425.
14. Higuchi T, Kikuchi M, Okazaki M. Hepatocellular carcinoma after transcatheter hepatic arterial embolization: a histopathologic study of 84 resected cases. Cancer 1994;73:2259-2267.
15. Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000;92:205- 216.
16. Tsuchida Y, Therasse P. Response evaluation criteria in solid tumors (RECIST): new guidelines. Med Pediatr Oncol 2001;37:1-3.
17. Kamel IR, Bluemke DA, Eng J, et al. The role of functional MR imaging in the assessment of tumor response after chemoembolization in patients with hepatocellular carcinoma. J Vasc Interv Radiol 2006;17:505-512.
18. Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42: 1208-1236.
19. Kamel IR, Bluemke DA, Ramsey D, et al. Role of diffusion-weighted imaging in estimating tumor necrosis after chemoemboliza- tion of hepatocellular carcinoma. AJR Am J Roentgenol 2003;181:708-710.
20. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 1986;42:121-130.
21. Ross BD, ChenevertTL, Rehemtulla A. Magnetic resonance imaging in cancer research. Eur J Cancer 2002;38:2147-2156.
22. Ross BD, Moffat BA, Lawrence TS, et al. Evaluation of cancer therapy using diffusion magnetic resonance imaging. Mol Cancer Ther 2003;2:581-587.
23. Lim HK, Han JK. Hepatocellular carcinoma: evaluation of therapeutic response to inter- ventional procedures. Abdom Imaging 2002; 27:168-179.
24. Takayasu K, Arii S, Matsuo N, et al. Comparison of CT findings with resected specimens after chemoembolization with iodized oil for hepatocellular carcinoma. AJR Am J Roentgenol 2000;175:699-704.
25. Murakami T, Nakamura H, Hori S, et al. Detection of viable tumor cells in hepatocel- lular carcinoma following transcatheter arterial chemoembolization with iodized oil: pathologic correlation with dynamic turbo- FLASH MR imaging with Gd-DTPA. Acta Radiol 1993;34:399-403.
26. Castrucci M, Sironi S, De Cobelli F, Salvioni M, Del Maschio A. Plain and gadolinium- DTPA-enhanced MR imaging of hepatocellu- lar carcinoma treated with transarterial che- moembolization. Abdom Imaging 1996;21:488-494.
27. Bartolozzi C, Lencioni R, Caramella D, Mazzeo S, Ciancia EM. Treatment ofhepato- cellular carcinoma with percutaneous etha- nol injection: evaluation with contrast-enhanced MR imaging. AJR Am J Roentgenol 1994;162:827-831.
28. Yu JS, Rofsky NM. Dynamic subtraction MR imaging of the liver: advantages and pitfalls. AJR Am J Roentgenol 2003;180:1351-1357.
29. Mardor Y, Pfeffer R, Spigelmann R, et al. Earlydetectionofresponse to radiationtherapy in patients with brain malignancies using conventional and high b-value diffusion- weighted magnetic resonance imaging. J Clin Oncol 2003;21:1094-1100.
30. Geschwind JF, Artemov D, Abraham S, et al. Chemoembolization ofliver tumor in a rabbit model: assessment of tumor cell death with diffusion-weighted MR imaging and histo- logic analysis. J Vasc Interv Radiol 2000; 11:1245-1255.