Assessing the relationship between health utilities, quality of life, and health services use in Alzheimer's disease

International Journal of Geriatric Psychiatry

Volumn 24, Issue 1, 2009, Pages 96-105

  Miller, Edward Alan ^a   Schneider, Lon S ^b   Rosenheck, Robert A ^c  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Correlates; Health Utilities Index; Quality of life; Service use

Indexed keywords

AGED; ALZHEIMER DISEASE; ALZHEIMER DISEASE COOPERATIVE STUDY ACTIVITIES OF DAILY LIVING SCALE; ALZHEIMER DISEASE RELATED QUALITY OF LIFE SCALE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; FEMALE; HEALTH CARE UTILIZATION; HEALTH SERVICE; HEALTH UTILITIES INDEX III; HISPANIC; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL CARE; MENTAL HEALTH; MINI MENTAL STATE EXAMINATION; NEUROPSYCHOLOGICAL TEST; NURSING HOME; OUTPATIENT CARE; QUALITY OF LIFE; RESIDENTIAL CARE; TREATMENT DURATION;

AGED; ALZHEIMER DISEASE; ANTIPSYCHOTIC AGENTS; CHI-SQUARE DISTRIBUTION; FEMALE; HEALTH SERVICES FOR THE AGED; HEALTH SERVICES NEEDS AND DEMAND; HOSPITALIZATION; HUMANS; LIKELIHOOD FUNCTIONS; MALE; NURSING HOMES; PATIENT ACCEPTANCE OF HEALTH CARE; PSYCHIATRIC STATUS RATING SCALES; QUALITY OF LIFE;

EID: 61749087278     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2160     Document Type: Article

References (44)

1. Alzheimer's Association. 2007. Alzheimer's Disease Facts and Figures, 2007. Alzheimer's Association: Washington, DC.
2. Beller SA, Overall JE. 1984. The Brief Psychiatric Rating Scale (BPRS) in geropsychiatric research: II. Representative profile patterns. J. Gerontol 39(2): 194-200.
3. Blaum CS, Ofstedal MB, Liang J. 2002. Low cognitive performance, comorbid disease, and task-specific disability: Findings from a nationally representative survey. J. Gerontol 57(8): M523-M531.
4. Chan DC, Kasper JD, Black BS, et al. 2003. Presence of behavioral and psychological symptoms predicts nursing home placement in community-dwelling elders with cognitive impairment in univariate but not multivariate analysis. J. Gerontol: Med Sci 58A: 548-554.
5. Cummings JL, Mega M, Gray K, et al. 1994. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44(12): 2308-2314.
6. Drummond M. 2001. Introducing economic and quality of life measurements into clinical studies. Ann Med 33(5): 344-349.
7. Feeny D, Furlong W, Torrance GW, et al. 2002. Multiattribute and single attribute utility functions for the Health Utilities Index Mark 3 system. Med Care 40(2): 113-128.
8. Fillenbaum G, Heyman A, Peterson B, et al. 2000. Frequency and duration of hospitalization of patients with AD based on Medicare data: CERAD XX. Neurology 54(3): 740-743.
9. Fillenbaum G, Heyman A, Peterson BL, et al. 2001. Use and cost of outpatient visits of AD patients: CERAD XXII. Neurology 56(12): 1706-1711.
10. Folstein MF, Folstein SE, McHugh PR. 1975. 'Mini-Mental State': A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr Res 12(3): 189-198.
11. Galasko D, Bennett D, Sano S, et al. 1997. An inventory to assess Activities of Daily Living for clinical trials in Alzheimer's disease. Alzheimer Dis Assoc Disord 22 (Suppl): S33-S39.
12. Gaugler JE, Edward AB, Femia EE, et al. 2000. Predictors of institutionalization of cognitively impaired elders: Family help and the timing of placement. J. Gerontology: Pysch Sci 55(4): P247-P255.
13. Gaugler JE, Leach CR, Clay T, et al. 2004. Predictors of nursing home placement in African Americans with dementia. J. Am Geriatr Soc 52(3): 445-452.
14. Gold M, Franks P, Erickson P. 1996. Assessing the health of the nation. The predictive validity of a preference-based measure and self-rated health. Med Care 34(2): 163-177.
15. Gonzalez-Salvador T, Lyketsos CG, Baker AS, et al. 2000. Quality of life of patients with dementia in long-term care. Int J Geriatr Psychiatry 15(2): 181-189.
16. Harrow BS, Mahoney DF, Mendelsoh AB, et al. 2004. Variation in cost of informal caregiving and formal-service use for people with Alzheimer's disease. Am J Alzheimers Dis Other Demen 19(5): 299-308.
17. Hill J, Fillit H, Thomas SK, et al. 2006. Functional impairment, healthcare costs and the prevalence of institutionalization in patients with Alzheimer's disease and other dementias. Pharmacoeconom 24(3): 265-280.
18. Horsman J, Furlong W, Feeny D, et al. 2004. The Health Utilities Index (HUI): concepts, measurement properties and applications. Health Qual Life Outcomes 1: 54.
19. Hux MJ, O'Brien BJ, Iskedjian M, et al. 1998. Relation between severity of Alzheimer's disease and costs of caring. Canadian Medical Association Journal 159(5): 457-465.
20. Kopec JA, Williams JI, To T, Austin P. 2000. Measuring population health: correlates of the Health Utilities Index among English and French Canadians. Can J Public Health 81(6): 465-470.
21. Lima VD, Kopec JA. 2005. Quantifying the effect of health status on health care utilization using a preference-based health measure. Soc Sci Med 60(3): 515-524.
22. Logsdon RG, Gibbons LE, McCurry SM, et al. 2002. Assessing quality of life in older adults with cognitive impairment. Psychosom Med 64(3): 510-519.
23. Manca A, Davies L, Burns A. 2002. Cost-effectiveness of therapeutics for Alzheimers disease. In Neuropsychopharmacology: - The Fifth Generation of Progress. Lippincott Williams & Wilkins: New York.
24. Mausbach BT, Coon DW, Depp C, et al. 2004. Ethnicity and time to institutionalization of dementia patients: A comparison of Latina and Caucasian female caregivers. J. Am Geriatr Soc 52(7): 1077-1084.
25. McKhann G, Drachman D, Folstein M, et al. 1984. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34(7): 939-944.
26. Miller EA, Schneider LS, Zbrozek A, Rosenheck R. 2008. Socio-demographic and clinical correlates of utility scores in Alzheimer's Disease. Value Health 11(7): 1120-1130.
27. Miller EA, Weissert WG. 2000. Predicting elderly people's risk of nursing home placement, hospitalization, functional impairment, and mortality: a synthesis. Med Care Res Rev 57(3): 259-297.
28. Montgomery RJ, Marquis J, Schaefer JP, Kosloski K. 2002. Profiles of respite use. Home Health Care Serv Q 21(3-4): 33-63.
29. Naglie G, Tomlinson G, Tansey C, et al. 2006. Utility-based quality of life measures in Alzheimer's disease. Qual Life Res 15(4): 631-643.
30. Neumann PJ, Kuntz KM, Leon J, et al. 1999. Health utilities in Alzheimer's disease: A cross-sectional study of patients and caregivers. Med Care 37(1): 27-32.
31. Neumann PJ, Sandberg EA, Araki SS, et al. 2000. A comparison of HUI2 and HUI3 utility scores in Alzheimer's disease. Med Decis Making 20(4): 413-422.
32. Phillips VL, Diwan S. 2003. The incremental effect of dementia-related problem behaviors on the time to nursing home placement in poor, frail, demented older people. J. Am Geriatr Soc 51(2): 188-193.
33. Porell FW, Carter M. 2005. Discretionary hospitalization of nursing home residents with and without Alzheimer's disease: A multi-level analysis. J. Aging Health 17(2): 207-238.
34. Rabins PV, Kasper JD, Kleinman L, et al. 1999. Concepts and methods in the development of the ADRQL: An instrument for assessing health-related quality of life in persons with Alzheimer's disease. J. Mental Health Aging 5: 33-48.
35. Rosenheck RA, Leslie DL, Sindelar J, et al. 2007. Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer Disease. Arch Gen Psychiatry 64(11): 1259-1268.
36. Schneider LS. 2001. Assessing outcomes in Alzheimer's Disease. Alzheimer Dis Assoc Disord 15(1): S8-S18.
37. Schneider LS, Tariot PN, Dagerman KS, et al. 2006. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. New Engl J Med 355(15): 1525-1538.
38. Schneider LS, Tariot PN, Lyketsos CG, et al. 2001. National Institute of Mental Health Clinical Antipsychotic Trials in Intervention Effectiveness (CATIE): Alzheimer's disease trial methodology. Am J Geriatr Psychiatry 9(4): 1-14.
39. Small GW, McDonnell DD, Brooks RL, et al. 2002. The impact of symptom severity on the cost of Alzheimer's Disease. J. Am Geriatr Soc 50(2): 321-327.
40. Smith GE, Kokmen E, O'Brien PC. 2000. Risk factors for nursing home placement in a population-based dementia cohort. J. Am Geriatr Soc 48(5): 519-525.
41. Sprenkl MD, Niewoehner DE, Nelson DB, et al. 2004. The Veterans Short Form 36 questionnaire is predictive of mortality and healthcare utilization in populations of veterans with a self-reported diagnosis of asthma and COPD. Chest 126(1): 81-89.
42. Sultzer DL, Davis SM, Tariot PN, et al. 2008. Clinical symptom responses to atypical antipsychotic medications in Alzheimer's Disease: Phase 1 outcomes from the CATIE-AD effectiveness trial. Am J Psychiatry 165(7): 844-854.
43. Taylor DH, Sloan FA. 2000. How much do persons with Alzheimer's disease cost Medicare? J Am Geriatr Soc 48(6): 639-646.
44. Toseland RW, McCallion P, Gerber T, et al. 2002. Predictors of health and human services use by persons with dementia and their family caregivers. Soc Sci Med 55(7): 1255-1266.