α-Adrenergic signalling activates protein kinase D and causes nuclear efflux of the transcriptional repressor HDAC5 in cultured adult mouse soleus skeletal muscle fibres

Journal of Physiology

Volumn 587, Issue 5, 2009, Pages 1101-1115

  Liu, Yewei ^a   Contreras, Minerva ^a   Shen, Tiansheng ^a   Randall, William R ^a   Schneider, Martin F ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; DIACYLGLYCEROL; GREEN FLUORESCENT PROTEIN; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 5; HISTONE H3; MYOCYTE ENHANCER FACTOR 2; PHENYLEPHRINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE D;

ACETYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FLEXOR MUSCLE; GENE EXPRESSION; MOTONEURON; MOUSE; MUSCLE CELL; MUSCLE CONTRACTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SLOW MUSCLE FIBER; SOLEUS MUSCLE; ADULT; CELL TRANSPORT; ENZYME ASSAY; HISTONE ACETYLATION; MOLECULAR DYNAMICS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; AGE FACTORS; ANIMALS; CELL NUCLEUS; CELLS, CULTURED; ENZYME ACTIVATION; HISTONE DEACETYLASES; MICE; MICE, MUTANT STRAINS; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; PROTEIN KINASE C; RECEPTORS, ADRENERGIC, ALPHA; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 61649094240     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.164566     Document Type: Article

References (33)

1. Auer A, von Blume J, Sturany S, von Wichert G, Van Lint J, Vandenheede J, Adler G & Seufferlein T (2005). Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling. Mol Biol Cell 16, 4375-4385.
2. Backs J, Backs T, Bezprozvannaya S, McKinsey TA & Olson EN (2008). Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4. Mol Cell Biol 28, 3437-3445.
3. Backs J, Song K, Bezprozvannaya S, Chang S & Olson EN (2006). CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. J Clin Invest 116, 1853-1864.
4. Bassel-Duby R & Olson EN (2006). Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem 75, 19-37.
5. Eberharter A & Becker PB (2002). Histone acetylation: A switch between repressive and permissive chromatin. Second in press series on chromatin dynamics. EMBO Report 3, 224-229.
6. Gschwendt M, Dieterich S, Rennecke J, Kittstein W, Mueller HJ & Johannes FJ (1996). Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett 392, 77-80.
7. Hardy S, Kitamura M, Harris-Stansil T, Dai Y & Phipps ML (1997). Construction of adenovirus vectors through Cre-lox recombination. J Virol 71, 1842-1849.
8. Harrison BC, Kim MS, van Rooij E, Plato CF, Papst PJ, Vega RB, McAnally JA, Richardson JA, Bassel-Duby R, Olson EN & McKinsey TA (2006). Regulation of cardiac stress signaling by protein kinase D1. Mol Cell Biol 26, 3875-3888.
9. Harrison BC, Roberts CR, Hood DB, Sweeney M, Gould JM, Bush EW & McKinsey TA (2004). The CRM1 nuclear export receptor controls pathological cardiac gene expression. Mol Cell Biol 24, 10636-10649.
10. Kim MS, Fielitz J, McAnally J, Shelton JM, Lemon DD, McKinsey TA, Richardson JA, Bassel-Duby R & Olson EN (2008). Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance. Mol Cell Biol 28, 3600-3609.
11. Kunkel MT, Toker A, Tsien RY & Newton AC (2007). Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter. J Biol Chem 282, 6733-6742.
12. Liu Y, Cseresnyes Z, Randall WR & Schneider MF (2001). Activity-dependent nuclear translocation and intranuclear distribution of NFATc in adult skeletal muscle fibers. J Cell Biol 155, 27-39.
13. Liu Y, Randall WR & Schneider MF (2005). Activity-dependent and -independent nuclear fluxes of HDAC4 mediated by different kinases in adult skeletal muscle. J Cell Biol 168, 887-897.
14. McGee SL, Howlett KF, Starkie RL, Cameron-Smith D, Kemp BE & Hargreaves M (2003). Exercise increases nuclear AMPK α2 in human skeletal muscle. Diabetes 52, 926-928.
15. McKinsey TA (2007). Derepression of pathological cardiac genes by members of the CaM kinase superfamily. Cardiovasc Res 73, 667-677.
16. McKinsey TA, Zhang CL, Lu J & Olson EN (2000). Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408, 106-111.
17. McKinsey TA, Zhang CL & Olson EN (2001). Identification of a signal-responsive nuclear export sequence in class II histone deacetylases. Mol Cell Biol 21, 6312-6321.
18. Matthews SA, Iglesias T, Rozengurt E & Cantrell D (2000). Spatial and temporal regulation of protein kinase D (PKD). EMBO J 19, 2935-2945.
19. Miska EA, Karlsson C, Langley E, Nielsen SJ, Pines J & Kouzarides T (1999). HDAC4 deacetylase associates with and represses the MEF2 transcription factor. EMBO J 18, 5099-5107.
20. Potthoff MJ, Wu H, Arnold MA, Shelton JM, Backs J, McAnally J, Richardson JA, Bassel-Duby R & Olson EN (2007). Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest 17, 2459-2467.
21. Rey O, Sinnett-Smith J, Zhukova E & Rozengurt E (2001 a). Regulated nucleocytoplasmic transport of protein kinase D in response to G protein-coupled receptor activation. J Biol Chem 276, 49228-49235.
22. Rey O, Young SH, Cantrell D & Rozengurt E (2001b). Rapid protein kinase D translocation in response to G protein-coupled receptor activation. Dependence on protein kinase C. J Biol Chem 276, 32616-32626.
23. Rozengurt E, Rey O & Waldron RT (2005). Protein kinase D signaling. J Biol Chem 280, 13205-13208.
24. Turner BM (2005). Reading signals on the nucleosome with a new nomenclature for modified histones. Nat Struct Mol Biol 12, 110-112.
25. van Lint J, Rykx A, Maeda Y, Vantus T, Sturany S, Malhotra V, Vandenheede JR & Seufferlein T (2002). Protein kinase D: An intracellular traffic regulator on the move. Trends Cell Biol 12, 193-200.
26. Vega RB, Harrison BC, Meadows E, Roberts CR, Papst PJ, Olson EN & McKinsey TA (2004). Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 24, 8374-8385.
27. Waldron RT & Rozengurt E (2003). Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. J Biol Chem 278, 154-163.
28. Wang L, Jackson W C, Steinbach P A & Tsien R Y (2004). Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci U S A 101, 16745-16749.
29. Wang QJ (2006). PKD at the crossroads of DAG and PKC signaling. Trends Pharmacol Sci 27, 317-323.
30. Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR & Molkentin JD (2004). Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 94, 110-118.
31. Wood CD, Marklund U & Cantrell DA (2005). Dual phospholipase C/ diacylglycerol requirement for protein kinase D1 activation in lymphocytes. J Biol Chem 280, 6245-6251.
32. 2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest 116, 623-626.
33. Zugaza JL, Sinnett-Smith J, Van Lint J & Rozengurt E (1996). Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. EMBO J 15, 6220-6230.