Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration

Optics Express

Volumn 17, Issue 5, 2009, Pages 4046-4060

  Chen, Yueli ^a,b,c   Vuong, Laurel N ^b   Liu, Jonathan ^a,c   Ho, Joseph ^b   Srinivasan, Vivek J ^a,c   Gorczynska, Iwona ^a,b,c   Witkin, Andre J ^b   Duker, Jay S ^b   Schuman, Joel ^d   Fujimoto, James G ^a,c  

^a USA   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; IMAGE RESOLUTION; OPHTHALMOLOGY; TOMOGRAPHY;

AGE-RELATED MACULAR DEGENERATION; IMAGING PROCESSING; PATHOLOGICAL CHANGES; RESEARCH PROTOTYPE; RETINAL PIGMENT EPITHELIUM; ULTRAHIGH RESOLUTION; ULTRAHIGH RESOLUTION OPTICAL COHERENCE TOMOGRAPHY; VOLUMETRIC IMAGING;

OPTICAL TOMOGRAPHY;

AGE; AGED; ARTICLE; ATROPHY; CASE REPORT; DRUSEN; FEMALE; FOURIER ANALYSIS; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PIGMENT EPITHELIUM; RETINA MACULA DEGENERATION; STATISTICS; THREE DIMENSIONAL IMAGING;

AGE FACTORS; AGED; AGED, 80 AND OVER; ATROPHY; FEMALE; FOURIER ANALYSIS; HUMANS; IMAGING, THREE-DIMENSIONAL; MACULAR DEGENERATION; MALE; MIDDLE AGED; RETINAL DRUSEN; RETINAL PIGMENT EPITHELIUM; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 61549140969     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.17.004046     Document Type: Article

References (52)

1. D. Huang, E.A. Swanson, C.P. Lin, J.S. Schuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
2. J.G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nature Biotechnology 21, 1361-1367 (2003).
3. W. Drexler, U. Morgner, F.X. Kartner, C. Pitris, S.A. Boppart, X.D. Li, E.P. Ippen, and J.G. Fujimoto, "In vivo ultrahigh-resolution optical coherence tomography," Opt. Lett. 24, 1221-1223 (1999).
4. W. Drexler, U. Morgner, R.K. Ghanta, F.X. Kartner, J.S. Schuman, and J.G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nature Medicine 7, 502-507 (2001).
5. M. Gloesmann, B. Hermann, C. Schubert, H. Sattmann, P.K. Ahnelt, and W. Drexler, "Histologic correlation of pig retina radial stratification with ultrahigh-resolution optical coherence tomography," Investigative Ophthalmology & Visual Science 44, 1696-703 (2003).
6. E.M. Anger, A. Unterhuber, B. Hermann, H. Sattmann, C. Schubert, J.E. Morgan, A. Cowey, P.K. Ahnelt, and W. Drexler, "Ultrahigh resolution optical coherence tomography of the monkey fovea. Identification of retinal sublayers by correlation with semithin histology sections," Experimental Eye Research 78, 1117-25 (2004).
7. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A.F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J Biomed Opt. 7, 457-463 (2002).
8. M.A. Choma, M.V. Sarunic, C.H. Yang, and J.A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183-2189 (2003).
9. J.F. de Boer, B. Cense, B.H. Park, M.C. Pierce, G.J. Tearney, and B.E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003).
10. R. Leitgeb, C.K. Hitzenberger, and A.F. Fercher, "Performance of Fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
11. M. Wojtkowski, T. Bajraszewski, P. Targowski, and A. Kowalczyk, "Real-time in vivo imaging by high-speed spectral optical coherence tomography," Opt. Lett. 28, 1745-1747 (2003).
12. N.A. Nassif, B. Cense, B.H. Park, M.C. Pierce, S.H. Yun, B.E. Bouma, G.J. Tearney, T.C. Chen, and J.F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12, 367-376 (2004).
13. B. Cense, N.A. Nassif, T.C. Chen, M.C. Pierce, S.H. Yun, B.H. Park, B.E. Bouma, G.J. Tearney, and J.F. de Boer, "Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography," Opt. Express 12, 2435-2447 (2004).
14. M. Wojtkowski, V.J. Srinivasan, T.H. Ko, J.G. Fujimoto, A. Kowalczyk, and J.S. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Optics Express 12, 2404-2422 (2004).
15. J.S. Schuman, C.A. Puliafito, and J.G. Fujimoto, Optical coherence tomography of ocular diseases, 2nd edition. (Thorofare, NJ: Slack Inc, 2004).
16. W. Drexler and J.G. Fujimoto, "State-of-the-art retinal optical coherence tomography," Prog Retin Eye Res. 27, 45-88 (2008).
17. W.R. Green and S.N. Key, 3rd, "Senile macular degeneration: a histopathologic study," Trans Am Ophthalmol Soc, 75 180-254 (1977).
18. R. Klein, B.E. Klein, S.C. Jensen, and S.M. Meuer, "The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study," Ophthalmology 104, 7-21 (1997).
19. D.S. Friedman, B.J. O'Colmain, B. Munoz, S.C. Tomany, C. McCarty, P.T. de Jong, B. Nemesure, P. Mitchell, and J. Kempen, "Prevalence of age-related macular degeneration in the United States," Arch Ophthalmol. 122, 564-72 (2004).
20. P.T. de Jong, "Age-related macular degeneration," N. Engl. J. Med. 355, 1474-85 (2006).
21. J.A. Chamberlin, N.M. Bressler, S.B. Bressler, M.J. Elman, R.P. Murphy, T.P. Flood, B.S. Hawkins, M.G. Maguire, and S.L. Fine, "The use of fundus photographs and fluorescein angiograms in the identification and treatment of choroidal neovascularization in the Macular Photocoagulation Study. The Macular Photocoagulation Study Group," Ophthalmology 96, 1526-34 (1989).
22. M.P.S. Group, "Persistent and recurrent neovascularization after laser photocoagulation for subfoveal choroidal neovascularization of age-related macular degeneration. Macular Photocoagulation Study Group," Arch Ophthalmol. 112, 489-99 (1994).
23. M.P.S. Group, "Visual outcome after laser photocoagulation for subfoveal choroidal neovascularization secondary to age-related macular degeneration. The influence of initial lesion size and initial visual acuity. Macular Photocoagulation Study Group," Arch Ophthalmol, 112, 480-8 (1994).
24. R.L. Avery, D.J. Pieramici, M.D. Rabena, A.A. Castellarin, M.A. Nasir, and M.J. Giust, "Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration," Ophthalmology 113, 363-372 (2006).
25. P.J. Rosenfeld, R.M. Rich, and G.A. Lalwani, "Ranibizumab: Phase III Clinical Trial Results," Ophthalmol Clin North Am. 19, 361-72 (2006).
26. A. Abdelsalam, L. Del Priore, and M.A. Zarbin, "Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression," Surv Ophthalmol. 44, 1-29 (1999).
27. M.A. Zarbin, "Current concepts in the pathogenesis of age-related macular degeneration," Arch Ophthalmol, 122, 598-614 (2004).
28. C.A. Puliafito, M.R. Hee, C.P. Lin, E. Reichel, J.S. Schuman, J.S. Duker, J.A. Izatt, E.A. Swanson, and J.G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).
29. M.R. Hee, C.R. Baumal, C.A. Puliafito, J.S. Duker, E. Reichel, J.R. Wilkins, J.G. Coker, J.S. Schuman, E.A. Swanson, and J.G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
30. M.R. Hee, C.A. Puliafito, C. Wong, J.S. Duker, E. Reichel, J.S. Schuman, E.A. Swanson, and J.G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).
31. J.S. Schuman, M.R. Hee, A.V. Arya, T. Pedut-Kloizman, C.A. Puliafito, J.G. Fujimoto, and E.A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current Opinion in Ophthalmology 6, 89-95 (1995).
32. M.R. Hee, C.A. Puliafito, C. Wong, J.S. Duker, E. Reichel, B. Rutledge, J.S. Schuman, E.A. Swanson, and J.G. Fujimoto, "Quantitative assessment of macular edema with optical coherence tomography," Archives of Ophthalmology 113, 1019-1029 (1995).
33. M.R. Hee, C.A. Puliafito, J.S. Duker, E. Reichel, J.G. Coker, J.R. Wilkins, J.S. Schuman, E.A. Swanson, and J.G. Fujimoto, "Topography of diabetic macular edema with optical coherence tomography," Ophthalmology 105, 360-370 (1998).
34. W. Drexler, H. Sattmann, B. Hermann, T.H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J.G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
35. T.H. Ko, J.G. Fujimoto, J.S. Duker, L.A. Paunescu, W. Drexler, C.R. Baumal, C.A. Puliafito, E. Reichel, A.H. Rogers, and J.S. Schuman, "Comparison of ultrahigh- and standard-resolution optical coherence tomography for imaging macular hole pathology and repair," Ophthalmology 111, 2033-2043 (2004).
36. T.H. Ko, J.G. Fujimoto, J.S. Schuman, L.A. Paunescu, A.M. Kowalevicz, I. Hartl, W. Drexler, G. Wollstein, H. Ishikawa, and J.S. Duker, "Comparison of ultrahigh- and standard-resolution optical coherence tomography for imaging macular pathology," Ophthalmology 112, 1922 e1-15 (2005).
37. E. Ergun, B. Hermann, M. Wirtitsch, A. Unterhuber, T.H. Ko, H. Sattmann, C. Scholda, J.G. Fujimoto, M. Stur, and W. Drexler, "Assessment of central visual function in Stargardt's disease/fundus flavimaculatus with ultrahigh-resolution optical coherence tomography," Investigative Ophthalmology & Visual Science 46, 310-316 (2005).
38. M.G. Wirtitsch, E. Ergun, B. Hermann, A. Unterhuber, M. Stur, C. Scholda, H. Sattmann, T.H. Ko, J.G. Fujimoto, and W. Drexler, "Ultrahigh resolution optical coherence tomography in macular dystrophy," American Journal of Ophthalmology 140, 976-983 (2005).
39. T.H. Ko, A.J. Witkin, J.G. Fujimoto, A. Chan, A.H. Rogers, C.R. Baumal, J.S. Schuman, W. Drexler, E. Reichel, and J.S. Duker, "Ultrahigh-resolution optical coherence tomography of surgically closed macular holes," Arch. Ophthalmol. 124, 827-836 (2006).
40. L.A. Paunescu, T.H. Ko, J.S. Duker, A. Chan, W. Drexler, J.S. Schuman, and J.G. Fujimoto, "Idiopathic juxtafoveal retinal telangiectasis: new findings by ultrahigh-resolution optical coherence tomography," Ophthalmology 113, 48-57 (2006).
41. C. Scholda, M. Wirtitsch, B. Hermann, A. Unterhuber, E. Ergun, H. Sattmann, T.H. Ko, J.G. Fujimoto, A.F. Fercher, M. Stur, U. Schmidt-Erfurth, and W. Drexler, "Ultrahigh resolution optical coherence tomography of macular holes," Retina 26, 1034-1041 (2006).
42. A.J. Witkin, T.H. Ko, J.G. Fujimoto, A. Chan, W. Drexler, J.S. Schuman, E. Reichel, and J.S. Duker, "Ultra-high resolution optical coherence tomography assessment of photoreceptors in retinitis pigmentosa and related diseases," American Journal of Ophthalmology 142, 945-952 (2006).
43. M. Wojtkowski, V. Srinivasan, J.G. Fujimoto, T. Ko, J.S. Schuman, A. Kowalczyk, and J.S. Duker, "Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 112, 1734-1746 (2005).
44. V.J. Srinivasan, D.C. Adler, Y. Chen, I. Gorczynska, R. Huber, J.S. Duker, J.S. Schuman, and J.G. Fujimoto, "Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head," Investigative Ophthalmology & Visual Science 49, 5103-5110 (2008).
45. B. Potsaid, I. Gorczynska, V.J. Srinivasan, Y. Chen, J. Jiang, A. Cable, and J.G. Fujimoto, "Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second," Opt Express 16, 15149-15169 (2008).
46. U. Schmidt-Erfurth, R.A. Leitgeb, S. Michels, B. Povazay, S. Sacu, B. Hermann, C. Ahlers, H. Sattmann, C. Scholda, A.F. Fercher, and W. Drexler, "Three-dimensional ultrahigh-resolution optical coherence tomography of macular diseases," Investigative Ophthalmology & Visual Science 46, 3393-3402 (2005).
47. V.J. Srinivasan, M. Wojtkowski, A.J. Witkin, J.S. Duker, T.H. Ko, M. Carvalho, J.S. Schuman, A. Kowalczyk, and J.G. Fujimoto, "High-definition and 3-dimensional imaging of macular pathologies with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology., 113, 2054-2065 (2006).
48. V.J. Srinivasan, B.K. Monson, M. Wojtkowski, R.A. Bilonick, I. Gorczynska, R. Chen, J.S. Duker, J.S. Schuman, and J.G. Fujimoto, "Characterization of outer retinal morphology with high-speed, ultrahigh-resolution optical coherence tomography," Investigative Ophthalmology & Visual Science 49, 1571-1579 (2008).
49. M. Szkulmowski, M. Wojtkowski, B. Sikorski, T. Bajraszewski, V.J. Srinivasan, A. Szkulmowska, J.J. Kaluzny, J.G. Fujimoto, and A. Kowalczyk, "Analysis of posterior retinal layers in spectral optical coherence tomography images of the normal retina and retinal pathologies," J. Biomed. Opt. 12, (2007).
50. S.L. Jiao, R. Knighton, X.R. Huang, G. Gregori, and C.A. Puliafito, "Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography," Opt. Express 13, 444-452 (2005).
51. S.L. Jiao, C.Y. Wu, R.W. Knighton, G. Gregori, and C.A. Puliafito, "Registration of high-density cross sectional images to the fundus image in spectral-domain ophthalmic optical coherence tomography," Opt. Express 14, 3368-3376 (2006).
52. I. Gorczynska, V.J. Srinivasan, L.N. Vuong, R.W. Chen, J.J. Liu, E. Reichel, M. Wojtkowski, J.S. Schuman, J.S. Duker, and J.G. Fujimoto, "Projection OCT fundus imaging for visualizing outer retinal pathology in non-exudative age related macular degeneration," Br. J. Ophthalmol, epub doi:10,1136 (2008).