Major salivary gland output differs between users and non-users of specific medication categories

Gerodontology

Volumn 25, Issue 4, 2008, Pages 210-216

  Wolff, Andy ^a,b   Zuk Paz, Limor ^c   Kaplan, Ilana ^d  

^a Saliwell Ltd ^*  (Israel)

^b Saliwell Ltd   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d RABIN MEDICAL CENTER   (Israel)

Author keywords

Medications; Parotid; Saliva; Submandibular; Xerostomia

Indexed keywords

ANTIHISTAMINIC AGENT; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS; GASTROINTESTINAL AGENT; HYPNOTIC SEDATIVE AGENT; TRANQUILIZER;

ADOLESCENT; ADULT; AGED; ARTICLE; COMPARATIVE STUDY; DRUG EFFECT; DRUG THERAPY; FEMALE; HUMAN; MALE; MIDDLE AGED; PAROTID GLAND; POLYPHARMACY; SALIVA; SALIVARY GLAND; SECRETION; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS SYSTEM AGENTS; DRUG THERAPY; FEMALE; GASTROINTESTINAL AGENTS; HISTAMINE ANTAGONISTS; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; PAROTID GLAND; POLYPHARMACY; SALIVA; SALIVARY GLANDS; SECRETORY RATE; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND; TRANQUILIZING AGENTS; YOUNG ADULT;

EID: 61449428144     PISSN: 07340664     EISSN: 17412358     Source Type: Journal    
DOI: 10.1111/j.1741-2358.2008.00223.x     Document Type: Article

References (37)

1. Dawes C. Physiological factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man. J Dent Res 1987 66 : 648 653.
2. Tabak LA, Levine MJ, Mandel ID, Ellison SA. Role of salivary mucins in the protection of the oral cavity. J Oral Pathol 1982 11 : 1 17.
3. Mandel ID. In defense of the oral cavity. In : Kleinberg I, Ellison SA, Mandel ID eds. Proceedings 'Saliva and Dental Caries'. New York, NY : Information Retrieval Inc. 1979 473 491.
4. Field EA, Longman LP, Bucknall R, Kaye SB, Highman SM, Edgar WM. The establishment of a xerostomia clinic: a prospective study. Br J Oral Maxillofacial Surg 1997 35 : 96 103.
5. Sreebny LM, Schwartz SS. A reference guide to drugs and dry mouth - 2nd edn. Gerodontology 1997 14 : 33 47.
6. Whaley K, Williamson J, Chisolm DM, Webb J, Mason DK, Buchanan WW. Sjögren's syndrome. 1. Sicca components. Q J Med 1973 6 : 79 304.
7. Narhi TO, Meurman JH, Ainamo A et al. Association between salivary flow rate and the use of systemic medication among 76-, 81- and 86 year-old inhabitants in Helsinki, Finland. J Dent Res 1992 71 : 1875 1880.
8. Schubert MM, Izutsu KT. Iatrogenic causes of salivary gland dysfunction. J Dent Res 1987 66 : 680 688.
9. Wolff A, Stahl B. Reference guide to xerogenic drugs in Israel. J Isr Dent Assoc 1999 16 : 51 76.
10. Scully C, Bagán JV. Adverse drug reactions in the orofacial region. Crit Rev Oral Biol Med 2004 15 : 221 239.
11. Janket SJ, Jones J, Rich S et al. The effects of xerogenic medications on oral mucosa among the Veterans Dental Study participants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 103 : 223 230.
12. Sreebny LM, Schwartz SS. Reference guide to drugs and dry mouth. Gerodontology 1986 5 : 75 99.
13. Thomson WM, Chalmers JM, Spencer AJ, Slade GD, Carter KD. A longitudinal study of medication exposure and xerostomia among older people. Gerodontology 2006 23 : 205 213.
14. Sreebny LM, Valdini A, Yu A. Xerostomia. Part II. Relationship to non-oral symptoms, drugs and diseases. Oral Surg Oral Med Oral Pathol 1989 68 : 419 427.
15. National Center for Health Statistics : Plan and operation of the Third National Health and Nutrition Examination Survery, 1988-1994. Vital Health Stat I 1994 32 : 1 407.
16. Osterberg T, Landahl S, Hedegard B. Salivary flow, saliva, pH and buffering capacity in 70-year-old men and women. Correlation to dental health, dryness in the mouth, disease and drug treatment. J Oral Rehabil 1984 11 : 157 170.
17. Parvinen T, Parvinen I, Larmas M. Stimulated salivary flow rate, pH and Lactobacillus and Yeast concentrations in medicated persons. Scand J Dent Res 1984 92 : 524 532.
18. Miller CS, Epstein JB, Hall EH, Sirois D. Changing oral care needs in the United States: the continuing need for oral medicine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001 91 : 34 44.
19. Smith RG, Burtner AP. Oral side-effects of the most frequently prescribed drugs. Spec Care Dent 1994 14 : 96 102.
20. Persson RE, Izutsu KT, Truelove EL, Persson R. Differences in salivary flow rates in elderly subjects using xerostomic medications. Oral Surg Oral Med Oral Pathol 1991 72 : 42 46.
21. Wu AJ, Ship JA. A characterization of major salivary gland flow rates in the presence of medications and systemic diseases. Oral Surg Oral Med Oral Pathol 1993 76 : 301 306.
22. Shannon I, Chauncey H. A parotid fluid collection device with improved stability characteristics. J Oral Ther Pharmacol 1967 4 : 93 97.
23. Wolff A, Begleiter A, Moskona D. A novel system of human submandibular/sublingual saliva collection. J Dent Res 1997 76 : 1782 1786.
24. Dixon WJ, ed. BMDP Statistical Software. Berkeley, CA : University of California Press, 1992.
25. Handleman SL, Barik JM, Saunders RH, Espeland MA. Hyposalivary drug use, whole stimulated salivary flow, and mouth dryness in older, long term care residents. Spec Care Dent 1989 9 : 12 18.
26. Grundbacher FJ. Variation in levels of immunoglobulins A, G and E in human saliva. Arch Oral Biol 1988 33 : 121 126.
27. Dawes C. Circadian rhythms in human salivary flow rate and composition. J Physiol 1972 220 : 529 545.
28. Edgar WM. Saliva: its secretion, composition and functions. Br Dent J 1992 172 : 305 318.
29. Sheuer E, Katz Y. Dry mouth as a side effect of medications. Harefuah 2000 139 : 471 475.
30. Bertram U. Xerostomia. Acta Odontol Scand 1967 25 : 11 126.
31. Andrew W. A comparison of age changes in salivary glands of man and of the rat. J Gerontol 1952 7 : 178 190.
32. Baum BJ. Evaluation of stimulated parotid saliva flow rate in different age groups. J Dent Res 1981 60 : 1292 1296.
33. Chauncey HH, Borkan G, Wayler A, Feller RP, Kapur KK. Parotid fluid composition in healthy aging males. Adv Physiol Sci 1981 28 : 323 328.
34. Heft MW, Baum BJ. Unstimulated and stimulated parotid salivary flow rate in individuals of different ages. J Dent Res 1984 63 : 1182 1186.
35. Scott J. Structure and function in aging human salivary glands - invited review. Gerontology 1986 5 : 149 158.
36. Pederson W, Schubert MM, Izutsu KT, Mersai T, Truelove E. Age-dependent decreases in human submandibular gland flow rates as measured under resting and post-stimulation conditions. J Dent Res 1985 64 : 822 825.
37. Tylenda CA, Ship JA, Fox PC, Baum BJ. Evaluation of submandibular salivary flow rate in different age groups. J Dent Res 1988 67 : 1225 1228.