Separation and purification of α-cyperone from cyperus rotundus with supercritical fluid extraction and high-speed counter-current chromatography

Separation Science and Technology

Volumn 44, Issue 3, 2009, Pages 712-721

  Shi, Xingang ^a   Wang, Xiao ^a   Wang, Daijie ^a   Geng, Yanling ^a   Liu, Jianhua ^a  

^a QILU UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Cyperone; Counter current chromatography; Cyperus rotundus; Preparative chromatography

Indexed keywords

CARBON DIOXIDE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; EFFLUENT TREATMENT; ESTERS; HEXANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; MASS SPECTROMETRY; METHANOL; ORGANIC SOLVENTS; PURIFICATION; SUPERCRITICAL FLUID EXTRACTION; SUPERCRITICAL FLUIDS;

BEIJING , CHINAS; BIOLOGICAL PRODUCTS; CHINESE MEDICINAL PLANTS; COUNTER-CURRENT CHROMATOGRAPHY; CYPERUS ROTUNDUS; ELECTRON IMPACT IONIZATION MASS SPECTROMETRIES; ESSENTIAL OIL; ETHYL ACETATES; FLOW-RATE; HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHIES; HPLC ANALYSIS; METHANOL WATERS; MOBILE PHASE; N HEXANES; ONE STEPS; PREPARATIVE CHROMATOGRAPHY; SEPARATION AND PURIFICATIONS; SUPERCRITICAL CARBON DIOXIDES; TARGET COMPOUNDS; TWO-PHASE SOLVENT SYSTEMS;

IMPACT IONIZATION;

CHROMATOGRAPHY; FLOW RATE; OIL; PLANT EXTRACT; PURIFICATION; SEPARATION; TEMPERATURE CONTROL;

EID: 61449231948     PISSN: 01496395     EISSN: 15205754     Source Type: Journal    
DOI: 10.1080/01496390802437081     Document Type: Article

References (19)

1. Committee of National Pharmacopoeia. (2005) Pharmacopoeia of P. R. China; Chemical Industry Press: Beijing, p. 181.
2. Huang, X.; Peng, G. (2003) Advances in the study of chemical constituents and pharmacology of Cyperus rotundus L. Zhong Yao Cai, 26: 65-68.
3. Weenen, H.; Nkunya, M.H.; Bray, D.H.; Mwasumbi, L.B.; Kinabo, L.S.; Kílimali, V.A. (1990) Antimalarial compounds containing an alpha, betaunsaturated Carbonyl moiety from Tanzanian medicinal plants. Planta Med., 56: 371-373.
4. Weenen, H.; Nkunya, M.H.; Bray, D.H.; Mwasumbi, L.B.; Kinabo, L.S.; Kilimali, V.A. (1990) Antimalarial activity of Tanzanian medicinal plants. Planta Med., 56: 368-370.
5. Wen, D.; Zhang, R.; Chen, S. (2003) Effect on contraction of the oxytocintreated isolated mice uterus of α-cyperone. J. Peking Unί, 35: 110-111.
6. Ito, Y. (2005) Golden rules and pitfalls in selecting optimum conditions for high-speed counter-current chromatography./. Chromatogr. A., 1065:145-168.
7. Li, H.B.; Chen, F. (2005) Simultaneous separation and purification of five bioactive coumarines from the Chinese medicinal plant Cnidium monnieri by high-speed counter-cuurent chromatodraphy. J. Sep. Sci, 28: 268-272.
8. Peng, J.; Fang, G.; Wu, Y. (2005) Supercritical fluid extraction of aurentiamide acetate from Pairinia villosa Juss and subsequent isolation by silica gel and high-speed counter-current chromatography. J. Chromatogr. A, 1083: 52-54.
9. Wang, X.; Li, F.; Zhang, FL; Geng, Y.; Yuan, J.; Jiang, T. (2005) Preparative isolation and purification of polymethoxylated flavones from Tangerine peel using high-speed counter-current chromatography. J. Chromatogr. A, 1090: 188-192.
10. Chen, L.J.; Games, D.E.; Jones, J. (2003) Isolation and identification of four flavonoid constituents from the seeds of Oroxylam indicum by high-speed counter-current chromatography. J. Chromatogr. A, 988: 95-99.
11. Zhang, D.L.; Teng, H.L.; Li, G.S.; Liu, K.; Su, Z.G. (2006) Separation and purification of Z ligustilide and senkyunolide A from Ligusticum chuanxiong Hort. with supercritical fluid extraction and high-speed counter-current chromatography. Sep. Sci Technol, 41 (15): 3397-3408,
12. Wei, Y.; Zhang, T.; Ito, Y. (2003) Preparative separation of rhein from Chinese traditional herb by repeated high-speed counter-current chromatography. J. Chromatogr. A, 1017: 125-130.
13. Wang, X.; Cheng. C; Sun, Q.; Li, F.; Zheng, C. (2005) Isolation and purification of four flavonoid constituents from the flowers of Paeonia suffruticosa by high-speed counter-current chromatography. J. Chromatogr. A, 1075: 127-131.
14. Du, Q.; Yuan, J. (2005) Preparation of triterpene saponins from the fruit of momordica charantia L. by high speed countercurrent chromatography (HSCCC). J. Liq. Chromatogr. & Rel. Technol., 28: 1717-1724.
15. Yan, J.; Tong, S.; Li, J. (2006) Preparative isolation and purification of amygdalin from prunus armeniaca L. with high recovery by high-speed countercurrent chromatography. J. Liq. Chromatogr. & Rel. Technol, 29: 1271-1279.
16. Sannomiya, M.; Rodrigues, CM.; Coelho, R.G.; Dos Santos, L.C.; Hiruma-Lima, CA.; Souza Brito, A.R.M.; Vilegas, W. (2004) Application of preparative high-speed counter-current chromatography for the separation of flavonoids from the leaves of Byrsonima crassa Niedenzu (TK). / Chromatogr. A, 1035: 47-51.
17. Zeng, J.; Li, Y.; Liu, L. (2001) Study on the extraction of Cyperus Rotundus L. by supercritical carbon dioxide. Chem. Eng., 29 (4): 11-14.
18. Liang, C; Luo, Y.; Zhong, Z.; Fu, J.; Su, C. (2004) Determination of α-cyperone in Rhizoma Cyperi oil by HPLC Zhong Yao Cai, 8: 578-580.
19. Ito, Y. (1988) In: Countercurrent Chromatography, Theory and Practice, Chapter 4. Mandava, N.B.; Ito, Y. eds.; Marcel Dekker: New York, 443.