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Volumn 11, Issue 2, 2009, Pages 301-304

Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROFORM; DEUTERIUM; HETEROCYCLIC COMPOUND; IMINE; WATER;

EID: 61449219936     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol8024499     Document Type: Article
Times cited : (8)

References (47)
  • 1
    • 0032820242 scopus 로고    scopus 로고
    • For general reviews on DCC see: a
    • For general reviews on DCC see: (a) Lehn, J.-M. Chem.-Eur. J. 1999, 5, 2455.
    • (1999) Chem.-Eur. J , vol.5 , pp. 2455
    • Lehn, J.-M.1
  • 23
    • 38149022713 scopus 로고    scopus 로고
    • For a general review on Systems Chemistry see: e
    • For a general review on Systems Chemistry see: (e) Ludlow, R. F.; Otto, S. Chem. Soc. Rev. 2008, 37, 101.
    • (2008) Chem. Soc. Rev , vol.37 , pp. 101
    • Ludlow, R.F.1    Otto, S.2
  • 32
  • 40
    • 24044531286 scopus 로고    scopus 로고
    • and references therein. For a general review on the chemistry and properties of azides see
    • For a general review on the chemistry and properties of azides see: Bräse, S.; Gil, C.; Knepper, K.; Zimmermann, V. Angew. Chem., Int. Ed. 2005, 44, 5188, and references therein.
    • (2005) Angew. Chem., Int. Ed , vol.44 , pp. 5188
    • Bräse, S.1    Gil, C.2    Knepper, K.3    Zimmermann, V.4
  • 42
    • 62149140253 scopus 로고    scopus 로고
    • 2O concentrations of 15 mM.
    • 2O concentrations of 15 mM.
  • 43
    • 62149119979 scopus 로고    scopus 로고
    • 1H NMR spectroscopy. The disappearance of the resonances arising from the aldehyde protons in 2 or m-tolualdehyde (δ = 9.9-10.1) and the simultaneous appearance of resonances arising from the imine protons in 3 or 4 (δ = 8.4-8.5) were monitored. Concentration vs time profiles were constructed by deconvolution of these resonances.
    • 1H NMR spectroscopy. The disappearance of the resonances arising from the aldehyde protons in 2 or m-tolualdehyde (δ = 9.9-10.1) and the simultaneous appearance of resonances arising from the imine protons in 3 or 4 (δ = 8.4-8.5) were monitored. Concentration vs time profiles were constructed by deconvolution of these resonances.
  • 44
    • 62149130494 scopus 로고    scopus 로고
    • von Kiedrowski, G. SimFit, A program for the analysis of kinetic data, Version 1.0; Ruhr-Universität Bochum: Germany, 1994
    • von Kiedrowski, G. SimFit, A program for the analysis of kinetic data, Version 1.0; Ruhr-Universität Bochum: Germany, 1994.
  • 45
    • 0000011153 scopus 로고    scopus 로고
    • We have demonstrated previously that recognition processes can be exploited in stabilizing otherwise unfavorable products and, hence, make unfavorable reaction processes proceed in a productive sense. See, for example: (a) Bennes, R, Philp, D, Spencer, N, Kariuki, B. M, Harris, K. D. M. Org. Lett. 1999, 1, 1087
    • We have demonstrated previously that recognition processes can be exploited in stabilizing otherwise unfavorable products and, hence, make unfavorable reaction processes proceed in a productive sense. See, for example: (a) Bennes, R.; Philp, D.; Spencer, N.; Kariuki, B. M.; Harris, K. D. M. Org. Lett. 1999, 1, 1087.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.