How to restore normal innate antitumor immunity in acute leukemia?

Leukemia Research

Volumn 33, Issue 5, 2009, Pages 613-

  Costello, Régis T ^a  

^a HÔPITAL NORD   (France)

Author keywords

Dendritic cells; Electroporation; Immunotherapy; Interferon; Leukemia; Natural killer cells; Tumour escape

Indexed keywords

ACUTE LEUKEMIA; CANCER IMMUNOTHERAPY; CELL FUNCTION; CYTOLYSIS; DENDRITIC CELL; EDITORIAL; ELECTROPORATION; HUMAN; INNATE IMMUNITY; LEUKEMIA CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR IMMUNITY;

ACUTE DISEASE; DENDRITIC CELLS; HUMANS; IMMUNITY, INNATE; KILLER CELLS, NATURAL; LEUKEMIA;

EID: 61449207210     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.09.019     Document Type: Editorial

References (6)

1. Lion E., Smits E.L.J.M., Berneman Z.N., and Van Tendeloo V.F.I. Acute myeloid leukemic cell lines loaded with synthetic dsRNA trigger IFN-secretion by human NK cells. Leukemia Res (2008)
2. Costello R.T., Fauriat C., Sivori S., Marcenaro E., and Olive D. NK cells: innate immunity against hematological malignancies?. Trends Immunol 25 6 (2004) 328-333
3. Costello R.T., Sivori S., Marcenaro E., Lafage-Pochitaloff M., Mozziconacci M.J., Reviron D., et al. Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia. Blood 99 10 (2002) 3661-3667
4. Fauriat C., Just-Landi S., Mallet F., Arnoulet C., Sainty D., Olive D., et al. Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCR dull phenotype induction. Blood 109 1 (2007) 323-330
5. Fauriat C., Moretta A., Olive D., and Costello R.T. Defective killing of dendritic cells by autologous natural killer cells from acute myeloid leukemia patients. Blood 106 6 (2005) 2186-2188
6. Moretta A., Locatelli F., and Moretta L. Human NK cells: from HLA class I-specific killer Ig like receptors to the therapy of acute leukemias. Immunol Rev 224 1 (2008) 58-69